Wintrobe's Clinical Hematology

Clinical Hematology
Contributors
Preface
Acknowledgments
Contents
Part I: Laboratory Hematology
Chapter 1: Examination of the Blood and Bone Marrow
Chapter 2: Clinical Flow Cytometry
Chapter 3: Cytogenetics
Chapter 4: Molecular Diagnosis in Hematology
Part II: The Normal Hematologic System
Section 1: Hematopoiesis
Chapter 5: Origin and Development of Blood Cells
Section 2: The Erythrocyte
Chapter 6: The Birth, Life, and Death of Red Blood Cells: Erythropoiesis, The Mature Red Blood Cell, and Cell Destruction
Section 3: Granulocytes and Monocytes
Chapter 7: Neutrophilic Leukocytes
Chapter 8: The Human Eosinophil
Chapter 9: Mast Cells and Basophils: Ontogeny, Characteristics, and Functional Diversity
Chapter 10: Monocytes, Macrophages, and Dendritic Cells
Section 4: The Lymphocytes
Chapter 11: Lymphocytes and Lymphatic Organs
Chapter 12: B Lymphocytes
Chapter 13: T Lymphocytes and Natural Killer Cells
Chapter 14: Effector Mechanisms In Immunity
Section 5: Hemostasis
Chapter 15: Megakaryocytes
Chapter 16: Platelet Structure and Function in Hemostasis and Thrombosis
Chapter 17: Platelet Function in Hemostasis and Thrombosis
Chapter 18: Blood Coagulation And Fibrinolysis
Chapter 19: Endothelium: Angiogenesis and the Regulation of Hemostasis
Part III: Transfusion Medicine
Chapter 20: Red Cell, Platelet, and White Cell Antigens
Chapter 21: Transfusion Medicine
Part IV: Disorders of Red Cells
Section 1: Introduction
Chapter 22: Anemia: General Considerations
Section 2: Disorders of Iron Metabolismand Heme Synthesis
Chapter 23: Iron Deficiency and Related Disorders
Chapter 24: Sideroblastic Anemias
Chapter 25: Hemochromatosis
Chapter 26: Porphyrias
Section 3: Hemolytic Anemia
Chapter 27: Hereditary Spherocytosis, Hereditary Elliptocytosis, And Other Disorders Associated With Abnormalities Of The Erythrocyte Membrane
Chapter 28: Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders
Chapter 29: Autoimmune Hemolytic Anemia
Chapter 30: Hemolytic Disease of the Fetus and Newborn
Chapter 31: Paroxysmal Nocturnal Hemoglobinuria
Chapter 32: Acquired Nonimmune Hemolytic Disorders
Section 4: Hereditary Disorders of Hemoglobin Structure and Synthesis
Chapter 33: Sickle Cell Anemia and Other Sickling Syndromes
Chapter 34: Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis
Chapter 35: Hemoglobins with Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias
Section 5: Other Red Cell Disorders
Chapter 36: Megaloblastic Anemias:Disorders Of Impaired Dna Synthesis
Chapter 37: Inherited Aplastic Anemia Syndromes
Chapter 38: Acquired Aplastic Anemia
Chapter 39: Red Cell Aplasia: Acquired And Congenital Disorders
Chapter 40: Congenital Dyserythropoietic Anemias
Chapter 41: Anemias Secondary to Chronic Disease and Systemic Disorders
Chapter 42: Anemias During Pregnancy and the Postpartum Period
Chapter 43: Anemias Unique to the Fetus and Neonate
Chapter 44: Erythrocytosis
Part V: Disorders of Hemostasis and Coagulation
Section 1: Introduction
Chapter 45: Diagnostic Approach to the Bleeding Disorders
Section 2: Thrombocytopenia
Chapter 46: Thrombocytopenia: Pathophysiology and Classification
Chapter 47: Thrombocytopenia Caused by Immunologic Platelet Destruction
Chapter 48: Thrombotic Thrombocytopenic Purpura, Hemolytic-Uremic Syndrome, and Related Disorders
Chapter 49: Miscellaneous Causes of Thrombocytopenia
Chapter 50: Bleeding Disorders Caused by Vascular Abnormalities
Chapter 51: Thrombocytosis And Essential Thrombocythemia
Chapter 52: Qualitative Disorders of Platelet Function
Section 4: Coagulation Disorders
Chapter 53: Inherited Coagulation Disorders
Chapter 54: Acquired Coagulation Disorders
Section 5: Thrombosis
Chapter 55: Thrombosis And Antithrombotic Therapy
Part VI: Benign Disorders of Leukocytes, the Spleen, and/or Immunoglobins
Chapter 56: Diagnostic Approach to Malignant and Nonmalignant Disorders of the Phagocytic and Immune Systems
Chapter 57: Neutropenia
Chapter 58: Qualitative Disorders of Leukocytes
Chapter 59: Lysosomal Abnormalities of the Monocyte–Macrophage System: Gaucher and Niemann-Pick Diseases
Chapter 60: Langerhans Cell Histiocytosis
Chapter 61: Pathology of Langerhans Cell Histiocytosis and Other Histiocytic Proliferations
Chapter 62: Infectious Mononucleosis and Other Epstein-Barr Virus–Related Disorders
Chapter 63: Primary Immunodeficiency Syndromes
Chapter 64: Acquired Immunodeficiency Syndrome
Chapter 65: Disorders of the Spleen
Chapter 66: Tumors of the Spleen
Part VII: Hematologic Malignancies
Section 1: General Aspects
Chapter 67: Hematopoietic Neoplasms: Principles of Pathologic Diagnosis
Chapter 68: Principles and Pharmacology of Chemotherapy
Chapter 69: Supportive Care in Hematologic Malignancies
Chapter 70: Immunotherapy
Chapter 71: Gene Therapy For Hematologic Disorders
Section 2: The Acute Leukemias
Chapter 72: Molecular Genetics of Acute Leukemia
Chapter 73: Diagnosis and Classification of the Acute Leukemias and Myelodysplastic Syndromes
Chapter 74: Acute Lymphoblastic Leukemia in Adults
Chapter 75: Acute Myeloid Leukemia in Adults
Chapter 76: Acute Lymphoblastic Leukemia in Children
Chapter 77: Acute Myelogenous Leukemia in Children
Chapter 78: Acute Promyelocytic Leukemia
Chapter 79: The Myelodysplastic Syndromes
Section 3: Myeloproliferative Disorders
Chapter 80: Pathology of The Myeloproliferative Neoplasms
Chapter 81: Chronic Myeloid Leukemia
Chapter 82: Polycythemia Vera
Chapter 83: Myelofibrosis
Chapter 84: Eosinophilic Neoplasms and Hypereosinophilic Syndrome
Chapter 85: Systemic Mastocytosis
Section 4: Lymphoproliferative Disorders
Chapter 86: Diagnosis and Classification of Lymphomas
Chapter 87: Molecular Genetic Aspects of Non-Hodgkin Lymphomas
Chapter 88: Non-Hodgkin Lymphoma In Adults
Chapter 89: Non-Hodgkin Lymphoma in Children
Chapter 90: Chronic Lymphocytic Leukemia
Chapter 91: Hairy Cell Leukemia
Chapter 92: Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sézary Syndrome
Chapter 93: Hodgkin Lymphoma in Adults
Chapter 94: Hodgkin Lymphoma in Children
Section 5: Plasma Cell Dyscrasias
Chapter 95: Practical Approach to Evaluation of Monoclonal Gammopathies
Chapter 96: Molecular Genetic Aspects of Plasma Cell Disorders
Chapter 97: Monoclonal Gammopathies Of Undetermined Significance And Smoldering Multiple Myeloma
Chapter 98: Multiple Myeloma
Chapter 99: Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis)
Chapter 100: WaldenstrÖm Macroglobulinemia
Chapter 101: Poems Syndrome, Cryoglobulinemia, and Heavy-Chain Disease
Part VIII: Transplantation
Chapter 102: Hematopoietic Cell Transplantation
Chapter 103: Hematopoietic Stem Cell Transplantation for Nonmalignant Disorders
Chapter 104: Allogenic Hematopoietic Stem Cell Transplantation (HCT) for Hematologic Malignancies
Chapter 105: Graft-Versus-Host Disease And Graft-VersusTumor Response
Chapter 106: Late Effects After Transplantation
Index
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