The best review of renal physiology available for USMLE Step 1--completely updated with the latest research
Written in a clear, concise, logical style, this trusted text reviews the fundamental principles of the structure, function and pathologies of the human kidney that are essential for an understanding of clinical medicine. Combining the latest research with a fully integrated teaching approach, the eighth edition of Vander's Renal Physiology features revised sections that explain how the kidneys affect other body systems and how they in turn are affected by these systems. Each chapter is filled with the tools you need to truly learn key concepts rather than merely memorize facts.
Features:
Begins with the basics and works up to advanced principles
Focuses on the logic of renal processes
Includes the most current research on the molecular and genetic principles underlying renal physiology
Explains the relationship between blood pressure and renal function
Presents the normal functions of the kidney with clinical correlations to disease states
Includes study questions with an answer key at the end of each chapter
Features learning aids such as flow charts, diagrams, key concept clinical examples, boxed statements to emphasize major points, learning objectives, and review questions with answers and explanations
Author(s): Douglas C. Eaton, John P. Pooler
Edition: 8th Edition
Publisher: McGraw-Hill Education / Medical
Year: 2013
Language: English
Pages: 213
Tags: Nephrology
Cover......Page 1
Title Page......Page 2
Copyright Page......Page 3
Contents......Page 6
Preface......Page 8
Renal Functions......Page 10
Anatomy of the Kidneys and Urinary System......Page 13
The Tubular System......Page 15
Basic Renal Excretory Processes......Page 21
Renal Blood Flow......Page 29
Flow, Resistance, and Blood Pressure in the Kidneys......Page 32
Glomerular Filtration......Page 33
Autoregulation......Page 42
The Clearance Concept......Page 46
Clearance Units......Page 47
Transepithelial Transport......Page 55
Receptor-Mediated Endocytosis and Transcytosis......Page 62
Proximal Tubule Reabsorption......Page 64
Overview......Page 71
Proximal Reabsorption of Organic Nutrients......Page 72
Proteins and Peptides......Page 73
Proximal Secretion of Organic Cations......Page 76
Proximal Secretion of Organic Anions......Page 77
pH Dependence of Passive Reabsorption or Secretion......Page 79
Urea......Page 80
Overview......Page 86
Individual Tubular Segments......Page 93
Urinary Concentration: The Medullary Osmotic Gradient......Page 102
Frequently Asked Questions......Page 108
The Goals of Regulation......Page 113
Sodium Excretion: The Cardiovascular Connection......Page 114
Major Controllers of Sodium Excretion: Sympathetic Stimulation......Page 118
Major Controllers of Sodium Excretion: The Renin-Angiotensin System......Page 119
Control of Water Excretion......Page 130
Regulation of Potassium Movement between the Intracellular and Extracellular Compartments......Page 140
Renal Potassium Handling......Page 143
Control of Potassium Excretion......Page 145
Overview......Page 155
Acid-Base Fundamentals......Page 156
Sources of Acids and Bases......Page 159
Renal Transport of Acids and Bases......Page 162
Regulation of the Renal Handling of Acids and Bases......Page 174
Acid-Base Disorders and Their Compensation......Page 175
Overview......Page 181
Effector Sites for Calcium Balance......Page 184
The Physiology of Phosphate......Page 187
Hormonal Control of Calcium and Phosphate......Page 188
Summary of Normal Calcium and Phosphate Regulation......Page 192
Magnesium Physiology and Renal Handling......Page 193
Answers to Study Questions......Page 196
Appendix A......Page 202
Appendix B......Page 204
A......Page 206
C......Page 207
H......Page 208
N......Page 209
P......Page 210
S......Page 211
V......Page 212
W......Page 213
