Upscaling of Bio-Nano-Processes: Selective Bioseparation by Magnetic Particles

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Despite ongoing progress in nano- and biomaterial sciences, large scale bioprocessing of nanoparticles remains a great challenge, especially because of the difficulties in removing unwanted elements during processing in food, pharmaceutical and feed industry at production level. This book presents magnetic nanoparticles and a novel technology for the upscaling of protein separation. The results come from the EU Project "MagPro2Life", which was conducted in cooperation of several european institutions and companies.

Author(s): Hermann Nirschl, Karsten Keller (eds.)
Series: Lecture Notes in Bioengineering
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2014

Language: English
Pages: 245
Tags: Biotechnology; Biomaterials; Food Science

Front Matter....Pages i-xvii
Introduction....Pages 1-12
Front Matter....Pages 13-13
New Advances in the Production of Iron-Based Nanostructures Manufactured by Laser Pyrolysis....Pages 15-37
Hydrophobic and Hydrophilic Magnetite Nanoparticles: Synthesis by Chemical Coprecipitation and Physico-Chemical Characterization....Pages 39-55
Magnetic Microgels: Synthesis and Characterization....Pages 57-76
Vesicles and Composite Particles by Rotating Membrane Pore Extrusion....Pages 77-96
Synthesis of Functionalized Magnetic Beads Using Spray Drying....Pages 97-116
Industrial Production, Surface Modification, and Application of Magnetic Particles....Pages 117-128
Front Matter....Pages 129-129
Magnetically Enhanced Centrifugation for Industrial Use....Pages 131-146
Design and Performance of a Pilot Scale High-Gradient Magnetic Filter Using a Mandhala Magnet and Its Application for Soy–Whey Protein Purification....Pages 147-173
Continuous Magnetic Extraction for Protein Purification....Pages 175-186
Front Matter....Pages 187-187
In Situ Magnetic Separation on Pilot Scale: A Tool for Process Optimization....Pages 189-211
An Industrial Approach to High Gradient Magnetic Fishing in the Food Industry....Pages 213-233
Front Matter....Pages 235-235
Conclusion....Pages 237-241
Back Matter....Pages 243-245