A variety of complementary techniques and approaches have been used to characterize peptide and protein unfolding induced by temperature, pressure, and solvent. Volume 62, Unfolded Proteins , assembles these complementary views to develop a more complete picture of denatured peptides and proteins. The unifying observation common to all chapters is the detection of preferred backbone confirmations in experimentally accessible unfolded states. Key Features * Peptide and protein unfolding induced by temperature, pressure, and solvent * Denatured peptides and proteins * Detection of preferred backbone confirmations in experimentally accessible unfolded states
Author(s): George D. Rose (Eds.)
Series: Advances in Protein Chemistry 62
Edition: 1
Publisher: Academic Press
Year: 2002
Language: English
Pages: 1-398
Content:
John T. Edsall and advances in protein chemistry
Pages xi-xiv
David S. Eisenberg, John Kuriyan, Frederic M. Richards
Getting to know u
Pages xv-xxi
George D. Rose
John T. Edsall (November 3, 1902–June 12, 2002)
Pages xxiii-xxiv
David S. Eisenberg
The expanded denatured state: An ensemble of conformations trapped in a locally encoded topological space Review Article
Pages 1-23
David Shortle
Identification and functions of usefully disordered proteins Review Article
Pages 25-49
A. Keith Dunker, Celeste J. Brown, Zoran Obradovic
Unfolded proteins studied by raman optical activity Review Article
Pages 51-90
L.D. Barron, E.W. Blanch, L. Hecht
What fluorescence correlation spectroscopy can tell us about unfolded proteins Review Article
Pages 91-109
Carl Frieden, Krishnananda Chattopadhyay, Elliot L. Elson
Unfolded peptides and proteins studied with infrared absorption and vibrational circular dichroism spectra Review Article
Pages 111-161
Timothy A. Keiderling, Qi Xu
Is polyproline II a major backbone conformation in unfolded proteins? Review Article
Pages 163-240
Zhengshuang Shi, Robert W. Woody, Neville R. Kallenbach
Toward a taxonomy of the denatured state: Small angle scattering studies of unfolded proteins Review Article
Pages 241-262
Ian S. Millett, Sebastian Doniach, Kevin W. Plaxco
Determinants of the polyproline II helix from modeling studies Review Article
Pages 263-282
Trevor P. Creamer, Margaret N. Campbell
Hydration theory for molecular biophysics Review Article
Pages 283-310
Michael E. Paulaitis, Lawrence Rpratt
Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance Review Article
Pages 311-340
H. Jane Dyson, Peter Ewright
Unfolded state of peptides Review Article
Pages 341-360
Xavier Daura, Alice Glättli, Peter Gee, Christine Peter, Wilfred F. Van Gunsteren
A new perspective on unfolded proteins Review Article
Pages 361-367
Robert L. Baldwin
Author index
Pages 369-387
Subject index
Pages 389-398
