Hammersmith Hospital, London, UK. Text provides a comprehensive overview of the molecular nature of tumor antigens recognized by antibodies, helper T lymphocytes, and cytotoxic T lymphocytes. Provides the basis for improved immunotherapy in cancer treatment. For clinicians and researchers. DNLM: Antigens, Neoplasm.
Author(s): Hans J Stauss, Yutaka Kawakami, Giorgio Parmiani
Series: The tumor immunology and immunotherapy series 3
Edition: 1
Publisher: Taylor & Francis
Year: 2003
Language: English
Pages: 220
City: London; New York
Book Cover......Page 1
Title......Page 4
Contents......Page 5
List of figures......Page 8
List of tables......Page 10
List of contributors......Page 12
Series preface......Page 16
Preface......Page 18
Animal models......Page 20
Mouse models in the recognition of tumor antigens......Page 22
Role of heat shock protein in chaperoning tumor antigens and modulating anti-tumor immunity......Page 39
Human tumor antigens recognized by class I HLA-restricted T cells......Page 54
WT1 as target for tumor immunotherapy......Page 56
Human melanoma antigens recognized by CD8+ T cells......Page 66
Squamous cell and adeno cancer antigens recognized by cytotoxic T lymphocytes......Page 94
Altered peptide ligands of tumor T-cell epitopes: implications for more effective vaccine therapy in human neoplasia......Page 116
Ex vivo and in situ detection of tumor-specific T-cell immunity with MHC tetramers......Page 130
Human tumor antigens recognized by class II HLA-restricted T cells......Page 150
Antigens of the MAGE family recognized by CD4+ T cells......Page 152
Melanoma antigens recognized by CD4+ T cells......Page 160
Human tumor antigens recognized by antibodies......Page 178
Human tumor antigens recognized by antibodies (SEREX)......Page 180
Antibodies to human tumor oncoproteins in cancer patients......Page 191
Antibody and T-cell responses to the NY-ESO-1 antigen......Page 210
Index......Page 218
