The study of stem cell research has recently gained the attention from a growing, multidisciplinary community of scientist; this exponential growth of interest is driven by the hope of discovering cures for several diseases through transplantation medicine. Trends in Stem Cells Biology and Technology aptly serves this developing community as it reveals new aspects of stem cell research by specifically covering studies focused on spermatogonial stem cells, uniparental embryonic stem cell lines, the generation of gametes from stem cells, reprogramming germ cells to stem cells, nuclear and somatic cell genetic reprogramming, tissue engineering and mechanotransduction of stem cells and finally the development of stem cell technologies for the treatment of deafness, heart disease, corneal injury and diabetes. With contributions by leading scientists and renowned scholars, Trends in Stem Cells Biology and Technology offers a wide audience cutting edge information at a crucial time in this ever expanding field.
Author(s): Ariff Bongso, Chui-Yee Fong (auth.), Hossein Baharvand (eds.)
Edition: 1
Publisher: Humana Press
Year: 2009
Language: English
Pages: 402
Tags: Cell Biology; Biotechnology; Biomedical Engineering
Front Matter....Pages i-xx
Human Embryonic Stem Cells: Their Nature, Properties, and Uses....Pages 1-17
Production of Uniparental Embryonic Stem Cell Lines....Pages 19-38
Parthenogenetic Embryonic Stem Cells in Nonhuman Primates....Pages 39-55
Nuclear and Somatic Cell Genetic Reprogramming....Pages 57-70
Reprogramming Male Germ Cells to Pluripotent Stem Cells....Pages 71-81
Pluripotent Stem Cell Epigenetics During Development and Cancer....Pages 83-100
Observing and Manipulating Pluripotency in Normal and Cloned Mouse Embryos....Pages 101-121
Current Developments in Genetically Manipulated Mice....Pages 123-136
Differentiating Gametes from Stem Cells....Pages 137-147
Spermatogonial Stem Cells....Pages 149-162
Regulated Transcripts and Coregulated microRNAs in Male Spermatogonial Stem Cells....Pages 163-175
Human Mesenchymal Stem Cells: Basic Biology and Clinical Applications for Bone Tissue Regeneration....Pages 177-190
Clinical Cell Therapy for Heart Disease....Pages 191-228
Embryonic Stem Cells, Cardiomyoplasty, and the Risk of Teratoma Formation....Pages 229-260
Neural Differentiation of Human Embryonic Stem Cells and Their Potential Application in a Therapy for Sensorineural Hearing Loss....Pages 261-282
Stem Cell Transplantation Supports the Repair of Injured Olfactory Neuroepithelium After Permanent Lesion....Pages 283-297
Strategies Toward Beta-Cell Replacement....Pages 299-317
Corneal Epithelial Stem Cells and Their Therapeutic Application....Pages 319-365
Tissue Engineered Scaffolds for Stem Cells and Regenerative Medicine....Pages 367-387
Mechanotransduction and Its Role in Stem Cell Biology....Pages 389-403
Back Matter....Pages 405-413