Cancer forms a large part of urological practice. Prostate cancer is the most significant and is the second most common cause of male cancer deaths with some 300,000 cases in the USA annually. Cancer of the bladder is also common. While treatment has been primarily surgical, recent years have seen an explosion of new drug therapies for urological cancers.All urologists, whether in training or in practice, need an up-to-date survey of the literature and key findings in this important and controversial field.This book takes each organ in turn (prostate, kidney, bladder, testis and penis) and tackles the controversies head-on by inviting chapters on various (often rival) treatments for each disease. Each section is then concluded by a commentary from the editor which draws together the various strands, outlines the principal areas of consensus and disagreement.Jonathan Waxman is an oncologist who specialises in urological tumours and has developed new treatments for prostate, bladder and kidney cancer and for terminal care, which are now part of standard practice. He founded the Prostate Cancer Charity and helped establish an all-party parliamentary group to improve cancer treatment and research throughout the UK.
Author(s): Jonathan Waxman
Edition: 1
Publisher: Wiley-Blackwell
Year: 2002
Language: English
Pages: 409
Cover......Page 1
TREATMENT OPTIONS IN UROLOGICAL CANCER......Page 6
Contents......Page 8
Contributors......Page 12
Preface......Page 16
Part 1 Kidney Cancer......Page 18
1 The Molecular Biology of Kidney Cancer......Page 20
2 Cytokines and Angiogenesis Inhibitor Treatments......Page 48
3 Surgical Management of Metastatic Renal Cancer......Page 66
Kidney Cancer: Commentary......Page 72
Part 2 Bladder Cancer......Page 74
4 The Molecular Biology of Bladder Cancer......Page 76
5 Surgery for Advanced Bladder Cancer......Page 101
6 Chemotherapy and Bladder Cancer......Page 115
7 Treatment Options in Superficial (pTa/pT1/CIS) Bladder Cancer......Page 135
Bladder Cancer: Commentary......Page 154
Part 3 Prostate Cancer......Page 156
8 The Molecular Biology of Prostate Cancer......Page 158
9 Surgical Pathology of Prostate Cancer......Page 177
10 Prostate Radiotherapy......Page 206
11 Prostate Cancer: Immediate vs. Deferred Treatment......Page 223
12 Hormone Therapy of Prostate Cancer......Page 237
13 Chemotherapy in Hormone Refractory Prostate Cancer......Page 254
14 Radical Prostatectomy......Page 270
15 The Case against Radical Surgery for Early Prostate Cancer......Page 281
Prostate Cancer: Commentary......Page 292
Part 4 Testicular Cancer......Page 294
16 Genetics of Adult Male Germ Cell Tumours......Page 296
17 Surveillance, Chemotherapy, and Radiotherapy for Stage 1 Testicular Germ Cell Tumours......Page 310
18 Chemotherapy of Testicular Cancer......Page 322
19 Salvage Chemotherapy Regimens for Relapsing Germ Cell Cancer......Page 334
20 Surgery for Testicular Cancer......Page 345
Testicular Cancer: Commentary......Page 367
Part 5 Penile Cancer......Page 368
21 Viral Agents in the Development of Penile Cancer......Page 370
22 Current Concepts in the Management of Penile Cancer......Page 383
Penile Cancer: Commentary......Page 399
Index......Page 400
