product iamge

Transporters as Targets for Drugs

This document was uploaded by one of our users. The uploader already confirmed that they had the permission to publish it. If you are author/publisher or own the copyright of this documents, please report to us by using this DMCA report form.

Download
Search on Amazon

Simply click on the Download Book button.

Yes, Book downloads on Ebookily are 100% Free.

Sometimes the book is free on Amazon As well, so go ahead and hit "Search on Amazon"

M. Bingham • S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte • A.W. Ravna • G. Sager • S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock • M.D. Andrews • A.D. Brown • P.V Fish • A. Stobie • F. Wakehut: Design of Monoamine Reuptake Inhibitors – SSRIs, SNRIs and NRIs

A. Hauck Newman • J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine’s Mechanism at the Dopamine Transporter

Z. Chen • J. Yang • P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni • J. Sörensen • H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges • S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc

R. Gilfillan • J. Kerr G. • Walker • G. Wishart: Glycine Transporters and Their Inhibitors

Author(s): Matilda Bingham, Susan Napier (auth.), Susan Napier, Matilda Bingham (eds.)
Series: Topics in Medicinal Chemistry
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2009

Language: English
Pages: 254
Tags: Medicinal Chemistry; Pharmacology/Toxicology; Organic Chemistry; Molecular Medicine

Front Matter....Pages I-XIV
Overview: Transporters as Targets for Drug Discovery....Pages 1-13
Membrane Transporters: Structure, Function and Targets for Drug Design....Pages 15-51
Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs....Pages 53-94
Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter....Pages 95-129
The Design, Synthesis and Structure–Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors....Pages 131-154
Molecular Imaging of Transporters with Positron Emission Tomography....Pages 155-186
Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c − ....Pages 187-222
Glycine Transporters and Their Inhibitors....Pages 223-247
Back Matter....Pages 249-253