Author(s): U.S. Dept of Health and Human Services
Series: SuDoc HE 20.7918:91/29
Publisher: The Agency
Year: 1992
Language: English
Pages: 126
TOXICOLOGICAL PROFILES FOR VANADIUM......Page 1
CONTENTS......Page 5
DISCLAIMER......Page 2
FOREWORD......Page 3
LIST OF FIGURES......Page 8
LIST OF TABLES......Page 9
1.2 HOW MIGHT I BE EXPOSED TO VANADIUM?......Page 10
1.5 IS THERE A MEDICAL TEST TO DETERMINE WHETHER I HAVE BEEN EXPOSED TO VANADIUM?......Page 11
2.1 INTRODUCTION......Page 12
2.2.1.1 Death......Page 13
2.2.1.2 Systemic Effects......Page 14
2.2.1.7 Genotoxic Effects......Page 20
2.2.2.2 Systemic Effects......Page 21
2.2.2.5 Developmental Effects......Page 29
2.2.3.5 Developmental Effects......Page 30
2.3.1.2 Oral Exposure......Page 31
2.3.2.1 Inhalation Exposure......Page 32
2.3.2.2 Oral Exposure......Page 33
2.3.3 Metabolism......Page 34
2.4 RELEVANCE TO PUBLIC HEALTH......Page 35
2.5 BIOMARKERS OF EXPOSURE AND EFFECT......Page 43
2.8 MITIGATION OF EFFECTS......Page 44
2.9 ADEQUACY OF THE DATABASE......Page 45
2.9.1 Existing Information on Health Effects of Vanadium......Page 46
2.9.2 Data Needs......Page 47
3.2 PHYSICAL AND CHEMICAL PROPERTIES......Page 50
4.1 PRODUCTION......Page 58
4.3 USE......Page 64
5.1 OVERVIEW......Page 65
5.2.1 Air......Page 66
5.2.2 Water......Page 67
5.2.3 Soil......Page 73
5.3.1 Transport and Partitioning......Page 74
5.3.2.1 Air......Page 75
5.4.1 Air......Page 76
5.4.4 Other Environmental Media......Page 77
5.5 GENERAL POPULATION AND OCCUPATIONAL EXPOSURE......Page 78
5.7.1 Data Needs......Page 79
6. ANALYTICAL METHODS......Page 81
6.1 BIOLOGICAL MATERIALS......Page 82
6.2 ENVIRONMENTAL SAMPLES......Page 86
6.3.1 Data Needs......Page 90
7. REGULATIONS AND ADVISORIES......Page 91
8. REFERENCES......Page 98
Bioconcentration Factor (BCF)......Page 114
Lethal Dose (LD50)......Page 115
Reproductive Toxicity......Page 116
User’s Guide......Page 117
Acronyms, Abbreviations, and Symbols......Page 122
PEER REVIEW......Page 126