The immune system is highly complex, it senses foreign invaders, thus protecting the body. The adaptive arm of the immune system confers long-term protection, whereas the innate immune system confers immediate protection. In the case of the immune system, the pattern recognition receptors offer various modes of sensing the molecular patterns associated with pathogens.
Toll-like receptors (TLRs) are important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link adaptive immunity with the innate immunity.
This book covers the role of TLRs in several vector-borne Diseases. Starting with an introduction to these diseases, the book explains the different types of receptors involved in these diseases. The diseases are then covered in separate chapters, including: malaria, lymphatic filariasis, visceral leishmaniasis, dengue fever, chikungunya, West Nile fever, and Japanese encephalitis.
The book is a handy reference for researchers and trainees involved in clinical medicine and infection control. It can also serve as supplementary reading material for Students undertaking courses in biotechnology, public health, entomology, immunology, epidemiology, and life sciences.
Author(s): Jayalakshmi Krishnan
Publisher: Bentham Science Publishers
Year: 2023
Language: English
Pages: 88
City: Singapore
Cover
Title
Copyright
End User License Agreement
Contents
Foreword
Preface
Introduction to Vector Borne Diseases
INTRODUCTION
CHIKUNGUNYA
LEISHMANIASIS
MALARIA
DENGUE
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
Pattern Recognition Receptors in Brain: Emphasis on Toll Like Receptors and their Types
INTRODUCTION
Brain and Pathogen Associated Molecular Patterns
Cerebral Malaria and TLRs
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
Malaria
INTRODUCTION
MALARIA: PATHOLOGY IN THE BRAIN BY NEUROIMAGING
NOVEL MALARIA BIOMARKERS
BLOOD BRAIN BARRIER IN CEREBRAL MALARIA
EXPERIMENTAL MOUSE MODELS FOR POTENTIAL TREATMENTS FOR HUMAN CM
INHIBITOR STUDIES
DIAGNOSTIC AND THERAPEUTIC MONITORING OF CEREBRAL MALARIA BY IMAGING
MALARIA AND TOLL-LIKE RECEPTORS IN THE BRAIN
MALARIA DRUGS AND MECHANISM OF ACTION
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
TLRs in Lymphatic Filariasis
INTRODUCTION
Lymphatic Filariasis and Inflammation
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
TLRs and Visceral Leishmaniasis
INTRODUCTION
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
Dengue Virus and Toll-Like Receptors
INTRODUCTION
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
Chikungunya Virus and Toll like Receptors
INTRODUCTION
EPIDEMIOLOGY OF CHIKV
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
West Nile Virus and Toll-like Receptors
INTRODUCTION
MicroRNAs and West Nile Virus
MyD88-/- and TLR-/- and WNV infection
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
Japanese Encephalitis and Toll-like Receptors
INTRODUCTION
JEV and Inflammation Through TLRs
MicroRNAs and JEV
Microglial Cells /MicroRNA and JEV
CONCLUDING REMARKS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENT
REFERENCES
Subject Index
Back Cover
