Ever since the association between cancer and thrombosis was reported by Jean-Baptiste Bouillaud in the early 19th century, cancer-associated thrombosis has remained a challenging domain of cancer management. Thrombosis can at times be a lead to cancer diagnosis, while it often complicates medical situations as a coexisting disorder. In this handbook, the contributors have compiled comprehensive information on the subject to provide the reader a comprehensive review of current medical literature and guidelines for cancer-associated thrombosis. Key Features -clinically oriented text for application in healthcare settings -current, evidence-based literature reviews and references -includes guidelines on VTE prophylaxis, heparin effects and more -includes information about special cases Thrombosis in Cancer: A Medical Professional's Guide to Cancer Associated Thrombosis is an informative handbook for a broad range of readers in medicine, including generalists, residents, and graduate-level trainees.
Author(s): Supratik Rayamajhi, Prajwal Dhakal, Shiva Shrotriya, Nishraj Basnet
Publisher: Bentham Science Publishers
Year: 2022
Language: English
Pages: 133
City: Sharjah
Cover
Title
Copyright
End User License Agreement
Contents
Foreword
Preface
List of Contributors
Overview of Cancer-Associated Thrombosis
Prajwal Dhakal1,* and Nishraj Basnet2
INTRODUCTION
EPIDEMIOLOGY
PROGNOSIS AND IMPACT OF VTE IN CANCER PATIENTS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Pathophysiology and Risk Factors for Cancer-Associated Thrombosis
Fawzi Abu Rous1,*, Layan A. Elkhatib2 and Prajwal Dhakal3
PATHOPHYSIOLOGY
RISK FACTORS
Tumor Related Factors
Treatment-Related Factors
Surgery
Hospitalization
Chemotherapy, Hormonal Therapy, and Radiotherapy
Supportive Therapy
Patient-Related Factors
BIOMARKERS
RISK MODELS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Impact of Venous Thromboembolism on Cancer Survival
Manoj Rai1,*
BACKGROUND
INCIDENCE
MORTALITY
VTE RECURRENCE
EFFECT OF ANTICOAGULATION IN CANCER
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Occult Cancer Workup in Idiopathic Venous Thromboembolism
Manoj Rai1,*
INTRODUCTION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Chemotherapy Induced Thrombosis
Manoj Rai1,* and Nishraj Basnet1
INTRODUCTION
PATHOPHYSIOLOGY
PROPHYLAXIS DURING CHEMOTHERAPY
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Catheter-Related Thrombosis in Cancer
Prajwal Dhakal1,*
INTRODUCTION
EPIDEMIOLOGY AND RISK FACTORS
PATHOPHYSIOLOGY AND TYPES OF CRT
Pericatheter Sheath or Fibrin Sleeve
Intraluminal Clot
Mural Thrombus
Other Causes
CLINICAL PRESENTATION
DIAGNOSIS
TREATMENT
Removal of Catheter
Systemic Anticoagulation
Other Options
PREVENTION OF CRT IN CANCER PATIENTS
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Management of Cancer-Associated Thrombosis
Lilit Karapetyan1,2, Calvin Abro2, Seda Grigoryan3 and Prajwal Dhakal1,*
INTRODUCTION
INITIAL TREATMENT
Anticoagulants
Low Molecular Weight Heparin
Factor Xa Inhibitors
Unfractionated Heparin
Warfarin
LONG TERM MANAGEMENT
ROLE OF DIRECT ORAL ANTICOAGULANTS
FINANCIAL ASPECTS OF CHOOSING ANTICOAGULATION
MECHANICAL DEVICES
Inferior Vena Cava Filters
IMPACT ON SURVIVAL WITH ANTI-THROMBOTIC THERAPY
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Special Cases in Cancer-Associated Thrombosis
Omar Albanyan1,* and Ikponmwosa Enofe1
INTRODUCTION
VTE and Thrombocytopenia
RECURRENT VTE
VTE IN RENAL IMPAIRMENT
INCIDENTAL VTE IN CANCER
MYELOPROLIFERATIVE DISORDERS AND VTE
BONE MARROW TRANSPLANTATION AND VTE
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Antitumor Effects of Heparin
Samanjit Kandola1 and Manoj Rai1,*
INTRODUCTION
TYPES OF HEPARIN
Unfractionated Heparin
Low-Molecular-Weight Heparin
Butanoylated Heparin
EFFECTS OF HEPARIN ON TUMOR
Anti-Angiogenesis Effects
Antiproliferative Effects
Effects on Immune System
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
VTE Prophylaxis
Fawzi Abu Rous1, Manoj Rai1,*, Osama Mosalem1, Layan El-khatib2, Calvin Abro1 and Abdullah Al-abcha1
INTRODUCTION
RISK STRATIFICATION
INPATIENT VTE PROPHYLAXIS
OUTPATIENT VTE PROPHYLAXIS
PERIOPERATIVE VTE PROPHYLAXIS
SOCIETY GUIDELINES
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Subject Index
Back Cover
