Thrombolysis in Pulmonary Embolism

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This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients requiring thrombolysis are identified; and the use of thrombolytic therapy in special situations such as in in-transit thrombus and pregnancy. Focusing on peripheral intravenous thrombolysis, which can performed safely and effectively in emergency departments, hospital wards, and intensive critical care units in tertiary and community hospitals, Thrombolysis in Pulmonary Embolism is a valuable resource for cardiologists, pulmonologists, and internists.

Author(s): Carlos Jerjes-Sánchez (auth.)
Edition: 1
Publisher: Springer International Publishing
Year: 2015

Language: English
Pages: XV, 236
Tags: Cardiology; Intensive / Critical Care Medicine; Emergency Medicine

Front Matter....Pages i-xv
Mechanisms of Thrombosis....Pages 1-17
Pharmacokinetics and Pharmacodynamics of Fibrinolytic Agents....Pages 19-39
Thrombolytic Therapy: Evidence-Based Results from Multicenter Control Trials....Pages 41-105
Patients for Thrombolysis....Pages 107-130
Anticoagulation as Adjunctive Treatment and One-Hour Alteplase Infusion....Pages 131-149
Current Guidelines and Recommendations for Thrombolysis Use in Pulmonary Embolism....Pages 151-174
Thrombolysis in Pulmonary Embolism....Pages 175-210
Thrombolysis in Special Situations....Pages 211-227
Back Matter....Pages 229-236