This book is the first of its kind to cover the underlying principles and biomedical applications of thermoacoustic tomography (TAT). Written in a tutorial format, it describes the fundamentals of TAT; details advanced approaches for quantitative TAT; explores the development of several image enhancing schemes including both software and hardware approaches; examines array-based TAT systems; considers high-resolution TAT approaches and combinations of TAT with other imaging methods; addresses contrast agent-based molecular TAT; and discusses clinical applications and animal studies in the areas of brain, breast, joint, thyroid, liver and vascular imaging. It is a valuable resource for students, academics, and industry specialists, including biomedical engineers, electrical engineers, physicists and mathematicians.
Author(s): Huabei Jiang
Series: IPEM–IOP Series in Physics and Engineering in Medicine and Biology
Publisher: IOP Publishing
Year: 2020
Language: English
Pages: 300
City: Bristol
PRELIMS.pdf
Preface
Acknowledgements
Author biography
Huabei Jiang
CH001.pdf
Chapter 1 Fundamentals of thermoacoustic tomography
1.1 Thermoacoustic effect
1.2 Image reconstruction methods
1.2.1 Delay-and-sum beam forming algorithm
1.2.2 A-line/B-mode image formation method
1.2.3 Iterative nonlinear algorithm
1.3 Instrumentation
References
CH002.pdf
Chapter 2 Quantitative thermoacoustic tomography
2.1 Recovery of tissue conductivity
Examples
2.2 Simultaneous recovery of absorbed microwave energy density and acoustic velocity
2.3 Simultaneous recovery of conductivity and elasticity
2.3.1 Image reconstruction algorithm
2.3.2 Numerical simulations
2.3.3 Phantom experiments
2.3.4 Results
2.3.5 Discussion and conclusion
References
CH003.pdf
Chapter 3 Image enhancement: software and hardware approaches
3.1 Dual mesh scheme
Examples
3.2 Adjoint sensitivity method
3.3 TVM scheme
3.4 Rigorous incident electric field and adaptive minimization strategy
3.4.1 Simulations and experiments
3.4.2 Discussion
3.5 Parallel computation
3.6 Compact dipole antenna
3.6.1 Methods and materials
3.6.2 Results and discussion
3.6.3 Conclusions
3.7 Compact microwave source
3.7.1 Methods and materials
3.7.2 Results and discussion
3.7.3 Conclusions
3.8 Anti-phase microwave excitation
3.8.1 Materials and methods
3.8.2 Results
3.8.3 Conclusions
References
CH004.pdf
Chapter 4 Transducer array-based TAT: 2D and 3D thermoacoustic imaging
4.1 Array-based TAT system and 2D imaging
4.1.1 Microwave source
4.1.2 128-Element ultrasound transducer arrays
4.1.3 Control electronics and data acquisition
4.1.4 System evaluation and experimental studies
4.2 3D Imaging
4.2.1 System description
4.2.2 Phantom experiments
Reference
CH005.pdf
Chapter 5 High-resolution and multi-modal approaches
5.1 High-resolution TAT
5.2 Multi-modal approaches—TAT/PAT
5.3 Multi-modal approaches—TAT/US
References
CH006.pdf
Chapter 6 Contrast agents-based molecular thermoacoustic imaging
6.1 Magnetic materials
6.1.1 Fe3O4/PANI and FA-Fe3O4/PANI
6.1.2 NMG2[Gd(DTPA)]
6.2 Carbon nanomaterials
6.3 Other materials
References
CH007.pdf
Chapter 7 Clinical applications and animal studies
7.1 Joint imaging
7.1.1 Rabbit knee joints
7.1.2 Healthy human finger joints
7.1.3 Diseased human finger joints
7.2 Brain imaging
7.2.1 In vivo rat brain
7.2.2 Phantom enclosed with ex vivo human skull
7.2.3 In vivo human brain
7.3 Imaging of thyroid
7.3.1 Thermoacoustic imaging system
7.3.2 Results and discussion
7.4 Liver imaging
7.5 Vascular imaging
7.6 Breast imaging
References
