The Regeneration Promise is a reader-friendly guide to the world of regenerative medicine and stem cell technology. It covers the history of stem cell technology as a general introduction to the subject and then continues with a description of the many known types of stem cells and how these can potentially be used to treat disease. The author explains the pros and cons of using stem cell technology to treat patients in simple and factual terms throughout the book while clarifying many stem cell myths. There is valuable advice for people considering undergoing stem cell therapy and also for those who are considering stem cell storage such as umbilical cord blood storage at the birth of a baby. The book also covers information on current research in stem cell technology and how this may be useful in the clinic, as promising regenerative medicine treatments emerge in the near future. The simple use of language with a clear explanation of scientific terms, where applicable, makes this book an accessible source of information for anyone interested in enhancing their general knowledge about regenerative medicine when considering such treatment options and understanding the debate surrounding stem cell technology and its use in disease therapy.
Author(s): Peter Hollands
Series: Medicine Demystified (1)
Publisher: Bentham Books
Year: 2020
Cover
Title
Copyright
End User License Agreement
Contents
Preface
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
Dedication
A Bit of History
Peter Hollands
INTERESTING TIMES
STEM CELLS ARE EVERYWHERE!
Bone Marrow Stem Cells
Back Again to 1956
Tissue Typing or ‘Tissue Matching’
From Embryos to Stem Cells
From Mouse to Man?
More Mouse Embryos!
Stem Cells in The Blood
Cord Blood Stem Cells
Cord Blood Transfusion
Human Embryonic Stem Cells
Adult or Fetal Stem Cells?
Umbilical Cord Tissue and Placental Tissue Stem Cells
Fat Stem Cells!
The Tooth Fairy and Stem Cells
‘Man Made’ Stem Cells
INITIAL CONCLUSIONS
KEY POINTS OF CHAPTER 1
Blood and Toil
Peter Hollands
‘BLOOD FORMING’ STEM CELLS
Bone Marrow Transplantation
Haploidentical Transplantation
Find the Match
Bone Marrow Stem Cell Banks
Preparation for Transplant
Transplant Time
Recovery
It’s Not Easy!
‘TISSUE FORMING’ STEM CELLS IN BONE MARROW
Clinical Trials
Four Phases
BONE MARROW STEM CELLS AND HEART ATTACK
BONE MARROW STEM CELLS AND AUTOIMMUNE DISEASE
THE RIGHT STEM CELL AND A HOLISTIC APPROACH
BONE MARROW STEM CELLS AND OSTEOARTHRITIS
Clinical Trials
BONE MARROW AND OTHER DISEASES
KEY POINTS OF CHAPTER 2
A Bouncing Baby!
Peter Hollands
CORD BLOOD STEM CELLS
Cord Blood Stem Cell Collection Process
Cord Blood Stem Cell Storage Options
Cord Blood Laboratory Processing
Cord Blood Stem Cells Pros and Cons
Cord Blood Stem Cell Double Transplants and Expansion
Quality not Quantity
Cord Blood Stem Cell Clinical Trial for Cerebral Palsy
Cord Blood Stem Cell Clinical Trial for Autism
KEY POINTS OF CHAPTER 3
Baby Blues
Peter Hollands
CHOICES
Public and Private Cord Blood Banks
The Development of Private Cord Blood Banking
The Development of Public Cord Blood Banking
Public or Private Cord Blood Storage?
Cord Blood Guidance
Whole or Processed?
More Questions
To Clamp or Not to Clamp? That is the Question…
The UK Royal Colleges
Umbilical Cord Blood Plasma
KEY POINTS OF CHAPTER 4
That's a Nice Vein
Peter Hollands
PERIPHERAL BLOOD STEM CELLS
Potential Problems
Improved Mobilisation Technology
Clinical Trials Using Peripheral Blood Stem Cells
KEY POINTS OF CHAPTER 5
The Vatican and More
Peter Hollands
A COMPLEX DEBATE
Human Embryonic Stem Cell Production
The Human Embryo
Is There an Elephant in The Room?
Clinical Trials
A FINAL NOTE OF OPTIMISM!
KEY POINTS OF CHAPTER 6
No One Likes the Dentist
Peter Hollands
OFF TO SEE THE DENTIST
Milk and Adult Teeth
Milk Teeth Collection
Stem Cells from Adult Teeth
Are There Enough Stem Cells?
Tooth Implants
Clinical Trial
KEY POINTS OF CHAPTER 7
Who Are You Calling Fat?
Peter Hollands
FAT: GOOD OR BAD?
Liposuction
Processing of Fat Stem Cells Using Enzymes
Processing of Fat Stem Cells Using A Mechanical Approach
Caution is Needed
Clinical Trials and ‘Freeze Young’
Fat Stem Cells and Osteoarthritis
KEY POINTS OF CHAPTER 8
A Human Touch
Peter Hollands
MAN-MADE
Good or Bad?
Organoids
Clinical Trials
KEY POINTS OF CHAPTER 9
Baby is Back!
Peter Hollands
STEM CELLS IN TISSUES RELATED TO PREGNANCY
Umbilical Cord Tissue
Clinical Trials of Cord Tissue Stem Cells
Placenta Stem Cells
Amniotic Membrane and Amniotic Fluid Stem Cells
Clinical Trials of Amniotic Membrane Stem Cells
Research and Clinical Trial of Amniotic Membrane Stem Cells
KEY POINTS OF CHAPTER 10
Kill or Cure?
Peter Hollands
STEM CELL TREATMENTS (CAVEAT EMPTOR: BUYER BEWARE)
The Regeneration Promise
Human Use
Using Your Own Stem Cells
Celebrity Endorsement
There is Hope
KEY POINTS OF CHAPTER 11
A Final Thought
Peter Hollands
SOME THINGS WORK SOME THINGS DO NOT
Cord Blood Transfusion
Platelet Rich Plasma (PRP)
Very Small Embryonic Like Stem Cells and Laser Technology
Cell Reprogramming
Exosomes
Quantum Medicine
Nanotechnology
3D Printing
Skeletal Muscle Stem Cells
Liver Stem Cells
Recent Progress in Stem Cell Therapy of Heart Disease
Anti-Ageing
A Final Thought
KEY POINTS OF CHAPTER 12
SUGGESTED FURTHER READING
USEFUL LINKS
Glossary
GLOSSARY
Subject Index
Back Cover
