The Physical Basis of Biochemistry: Solutions Manual to the Second Edition offers solutions to the problem sets from the second edition of The Physical Basis of Biochemistry. The Physical Basis of Biochemistry is an introduction to the philosophy and practice of an interdisciplinary field in which biological systems are explored using the quantitative perspective of the physical scientist. As with the first edition, the idea that a fundamental understanding of the basic physical principles underlying chemical biological systems is vital remains the focus of this second edition. This new edition of The Physical Basis of Biochemistry has substantial new material added with respect to models at the simple molecular level (including van der Waals gases and virial treatments) which is tied to coverage of models of polymer thermo-dynamics. The second edition is partitioned into five sections: the central concept that science is a way of looking at the world; the physical under-pinnings of biophysical chemistry with an emphasis first on energy, work and forces of biological importance; exploring how models applicable to molecular biophysics are constructed; the three-dimensional potential energy surface put into motion; and a succinct discussion of the bio-physical methods used to evaluate structure and function in biological systems. Additionally, a section of appendices continues to serve the purpose of presenting some review information and certain topics in detail. The Physical Basis of Biochemistry will be of interest to quantitatively-oriented biologists as well as aspiring chemists, physicists, and engineers with an interest in biological systems.
Author(s): Peter R. Bergethon, Kevin Hallock (auth.)
Edition: 1
Publisher: Springer-Verlag New York
Year: 2011
Language: English
Pages: 146
Tags: Biochemistry, general;Biophysics and Biological Physics;Physical Chemistry;Biomedicine general
Front Matter....Pages i-x
Front Matter....Pages 1-1
Philosophy and Practice of Biophysical Study....Pages 3-7
Overview of the Biological System Under Study – Descriptive Models....Pages 9-9
Physical Thoughts, Biological Systems – The Application of Modeling Principles to Understanding Biological Systems....Pages 11-13
Probability and Statistics....Pages 15-21
Front Matter....Pages 23-23
Physical Principles: Energy – The Prime Observable....Pages 25-27
Biophysical Forces in Molecular Systems....Pages 29-33
An Introduction to Quantum Mechanics....Pages 35-38
Chemical Principles....Pages 39-41
Measuring the Energy of a System: Energetics and the First Law of Thermodynamics....Pages 43-48
Entropy and the Second Law of Thermodynamics....Pages 49-52
Which Way Did That System Go? The Gibbs Free Energy....Pages 53-55
The Thermodynamics of Phase Equilibria....Pages 57-59
Front Matter....Pages 61-61
Water: A Unique Structure, a Unique Solvent....Pages 63-63
Ion-Solvent Interactions....Pages 65-66
Ion-Ion Interactions....Pages 67-70
Lipids in Aqueous Solution....Pages 71-72
Macromolecules in Solution....Pages 73-74
Molecular Modeling − Mapping Biochemical State Space....Pages 75-79
The Electrified Interphase....Pages 81-84
Front Matter....Pages 85-85
Transport and Kinetics: Processes Not at Equilibrium....Pages 87-88
Front Matter....Pages 85-85
Flow in a Chemical Potential Field: Diffusion....Pages 89-90
Flow in an Electrical Field: Conduction....Pages 91-93
Forces Across Membranes....Pages 95-96
Kinetics − Chemical Kinetics....Pages 97-101
Bioelectrochemistry – Charge Transfer in Biological Systems....Pages 103-105
Front Matter....Pages 107-107
Separation and Characterization of Biomolecules Based on Macroscopic Properties....Pages 109-114
Determining Structure by Molecular Interactions with Photons: Electronic Spectroscopy....Pages 115-119
Determining Structure by Molecular Interactions with Photons: Scattering Phenomena....Pages 121-127
Analysis of Structure – Microscopy....Pages 129-133
Front Matter....Pages 135-135
Physical Constants....Pages 137-137
Back Matter....Pages 139-143
