The papers assembled in this volume are based on the symposium on "The Biochemistry of Gene Expression in Higher Organisms" which was held at the University of Sydney from May 14-19, 1972. Many symposia have been held on the control of gene expression in prokaryotes but to date considerably less attention has been paid to eukaryotic organisms. It has been appreciated only recently that some of the information gained from the study of prokaryotes is directly applicable to eukaryotes; however, it is now realized that the principles of the control mechanisms of gene expression in these two classes of organism, differ considerably. This symposium was organized in an effort to bring together workers from widely different fields concerned with gene expression, with the aim of circum scribing the current concepts and speculating on future developments in studies on the mechanisms which control and modulate gene expression, in the widest sense, in eukaryotes. This volume contains all the 36 papers presented at the symposium. In a few instances the sequence of contributions has been changed to provide the reader with a more logical presentation. In addition, three papers which were not actually presented at the symposium, have been included in this volume. These three papers were not read because last-minute hitches prevented speakers from attending.
Author(s): W. J. Peacock (auth.), J. K. Pollak, J. Wilson Lee (eds.)
Edition: 1
Publisher: Springer Netherlands
Year: 1973
Language: English
Pages: 658
Tags: Biochemistry, general
Front Matter....Pages i-ix
Front Matter....Pages 1-1
Chromosome Structure and Units of Function in Higher Organisms....Pages 3-20
Transgenosis of Bacterial Genes from Escherichia Coli to cultures of Haploid Lycopersicon Esculentum and Haploid Arabidopsis Thaliana Plant Cells....Pages 21-37
Sequences in Genetic Nucleic Acids....Pages 38-55
Mutations at the End of the Iso-l-cytochrome c Gene of Yeast....Pages 56-86
Front Matter....Pages 87-87
RNA Polymerases and Transcriptive Specificity in Eukaryotic Organisms....Pages 89-104
The control of Gene Expression by Membrane Organization in Saccharomyces Cerevisiae ....Pages 105-116
Transcription and Translation in Mammalian Cells....Pages 117-141
Isolated Chromatin in the Study of Gene Expression....Pages 142-163
Structural Modifications of Histones in Cultured Mammalian Cells....Pages 164-176
The Role of Histones in Avian Erythropoiesis....Pages 177-190
Chromosomal Components in Relation to the Differentiation of Avian Red Blood Cells....Pages 191-205
Mechanism of Glucocorticoid Hormone Action and of Regulation of Gene Expression in Cultured Mammalian Cells....Pages 206-224
Regulation of transcription by glucocorticosteroids....Pages 225-241
A Control Mechanism in Gene Expression of Higher Cells Operating at the Termination Step in Protein Synthesis....Pages 242-259
The Mechanism and Control of the Biosynthesis of α -Lactalbumin by the Mammary Gland....Pages 260-273
Changes in Protein Synthesis and Degradation Involved in Enzyme Accumulation in Differentiating Liver....Pages 274-284
Front Matter....Pages 285-285
Obligatory Requirement for DNA Synthesis During Myogenesis, Erythrogenesis and Chondrogenesis....Pages 287-304
The Dependence of Gene Expression on Membrane Assembly....Pages 305-319
Patterns of Gene Activity in Larval Tissues of the Blowfly, Calliphora ....Pages 320-332
Hormonal and Environmental Modulation of Gene Expression in Plant Development....Pages 333-356
Front Matter....Pages 285-285
DNA and RNA Synthesis During Growth by Cell Expansion in Vicia Faba Cotyledons....Pages 357-366
Front Matter....Pages 367-367
Induction of δ-Aminolevulinic Acid Synthetase in Perfused Rat Liver by Drugs, Steroids, Lead and Adenosine-3′, 5′-Monophosphate....Pages 369-378
The Anaemia-Induced Reversible Switch From Haemoglobin A to Haemoglobin C in Goats and Sheep: The Two Haemoglobins Are Present in the Same Cell during the Changeover....Pages 379-392
Gene Expression in Liver Endoplasmic Reticulum....Pages 393-409
The Use of Neurological Mutants as Experimental Models....Pages 410-422
Front Matter....Pages 423-423
The Phenomenology of Cytoplasmic Genetics in Yeast: A Proposal for an Autonomy of Mitochondrial Membranes and the Determinism of Nucleo-cytoplasmic Genetic Interactions....Pages 425-442
Location of DNAs Coding for Various Kinds of Chloroplast Proteins....Pages 443-456
Nuclear Genes Controlling Chloroplast Development in Barley....Pages 457-478
Gene Expression in Chloroplasts and Regulation of Chloroplast Differentiation....Pages 479-503
Products of Chloroplast DNA-Directed Transcription and Translation....Pages 504-522
Front Matter....Pages 523-523
The Relevance of Immunology to the Biochemistry of Gene Expression....Pages 525-531
The Reaction of Antigen With Lymphocytes....Pages 532-541
Synthesis, Transport and Secretion of Immunoglobulins in Lymphoid Cells....Pages 542-554
Molecular and Cellular Mechanisms of Clonal Selection....Pages 555-573
Antibody Diversification: the Somatic Mutation Model Revisited....Pages 574-592
An Alternate Mechanism for Immune Recognition....Pages 593-605
The Clonal Development of Antibody-Forming Cells....Pages 606-611
Immunoglobulin Gene Expression in Murine Lymphoid Cells....Pages 612-628
Structure and Function of Lymphocyte Surface Immunoglobulin....Pages 629-647
Back Matter....Pages 649-657
