The most current, comprehensive, and authoritative guide to surgical oncology
As cancer care has continued to evolve in the 21st century, so too has the management of specific neoplasms through surgery. Keeping pace with this dynamic subspecialty calls for a state-of-the-art resource that combines oncologic principles with surgical treatment plans. Textbook of General Surgical Oncology is just such a resource.
Encyclopedic in scope and featuring the insights of more than 300 thought leaders in their respective surgical and medical oncology disciplines, this indispensable guide illuminates both common and uncommon issues. The book’s 165 chapters span virtually every clinical scenario oncologic surgeons are likely to encounter, resulting in the most complete, rigorous overview of surgical oncology available.
Textbook of General Surgical Oncology begins with an in-depth review of the general concepts and principles of genomics, epigenetics, pathology, targeted therapy, regional therapy, and patient safety in surgical oncology. The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, head/neck, lung, mediastinum, breast, pleura, peritoneum—plus tumors that affect various systems, including the endocrine, gastrointestinal, and hepatobiliary.
Features
• Each chapter is written by an internationally recognized expert on the topic
• Outstanding review for the new Complex General Surgical Oncology certification examination
• Helps prepare trainees of various surgical subspecialties for their in-training examinations and surgical board exams
• Numerous full-color illustrations highlight relevant anatomy and surgical technique
Author(s): Shane Y. Morita, Charles M. Balch, V. Suzanne Klimberg, Timothy M. Pawlik, Mitchell C. Posner, Kenneth K. Tanabe
Publisher: McGraw-Hill Education
Year: 2017
Language: English
Commentary: CONVERTED PDF
Pages: 2900
Tags: Surgical Oncology
Cover Page......Page 1
Cover Page......Page 3
Title Page......Page 4
Copyright Page......Page 6
Dedication......Page 8
Contents......Page 9
Contents......Page 22
Section Editors......Page 26
Contributors......Page 79
Foreword......Page 80
Preface......Page 81
Acknowledgments......Page 82
I ONCOLOGIC CONCEPTS PRINCIPLES......Page 83
1. Defining the Specialty of Surgical Oncology......Page 89
2. Evolution of Surgical Oncology......Page 101
3. American Board of Surgery Certificate in Complex General Surgical Oncology: Rationale and History......Page 107
4. Outcomes Research......Page 119
5. Patient Safety in Surgical Oncology......Page 125
6. Pathology......Page 144
7. Cancer Epigenetics......Page 161
8. Genomics and Cancer Biomarkers......Page 190
9. Targeted Therapy......Page 203
10. Regional Cancer Therapy: Isolation Perfusion, Isolation Infusion, and Local Ablative Techniques......Page 226
11. Radiation Oncology: Concepts and Techniques......Page 242
II MELANOMA AND OTHER CUTANEOUS MALIGNANCIES......Page 243
12. Melanoma Staging......Page 264
13. Biopsy and Definitive Excision of Primary Cutaneous Melanomas......Page 280
14. Sentinel Lymph Node Biopsy for Melanoma......Page 292
15. Surgical Management of Metastatic Melanoma (Stage III and IV Disease)......Page 307
16. Surgical Management of Locoregionally Recurrent and in-Transit Melanoma......Page 322
17. Radiation Therapy for Metastatic Melanoma......Page 334
18. Systemic Treatment for Stage IV Melanoma......Page 357
19. Melanoma Guidelines for Management and Follow-up......Page 368
20. Noncutaneous Melanoma......Page 379
21. Uncommon Cutaneous Malignancies......Page 390
22. Basal Cell Carcinoma......Page 406
23. Squamous Cell Carcinoma......Page 420
III SARCOMA AND OTHER SOFT TISSUE NEOPLASMS......Page 421
24. Soft Tissue Sarcoma: Epidemiology, Predisposing and Genetic Factors, and Staging......Page 427
25. Pathology of Soft Tissue Sarcomas......Page 461
26. Extremity and Trunk Sarcomas......Page 486
27. Retroperitoneal Sarcomas......Page 501
28. Desmoid Tumors......Page 520
29. Benign Soft Tissue Tumors and Reactive Lesions......Page 539
30. Metastatic Sarcoma......Page 566
IV ENDOCRINE......Page 567
31. Thyroid Nodules......Page 586
32. Locally Advanced and Aggressive Thyroid Cancer......Page 599
33. Papillary Thyroid Carcinoma......Page 628
34. Medullary Thyroid Cancer......Page 644
35. Follicular Thyroid Carcinoma......Page 652
36. Hrthle Cell Carcinoma......Page 662
37. Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve......Page 678
38. Thyroid Lymphoma......Page 687
39. Parathyroid Carcinoma......Page 698
40. Multiple Endocrine Neoplasia Type 1......Page 703
41. Adrenal Incidentaloma......Page 716
42. Cushings Syndrome......Page 730
43. Pheochromocytoma......Page 741
44. Adrenocortical Cancer......Page 749
45. Gastrointestinal Neuroendocrine Tumors......Page 775
46. Insulinoma......Page 784
47. Gastrinoma......Page 811
48. Multiple Endocrine Neoplasia Type 2......Page 827
49. Other Pancreatic Neuroendocrine Tumors......Page 839
50. Non-MEN Thyroid Cancer Syndromes......Page 846
51. Ectopic ACTH Syndrome......Page 858
V HEAD AND NECK......Page 859
52. Skin Cancer of the Head and Neck......Page 888
53. Head and Neck Cancers from an Unknown Primary......Page 898
54. Nasopharyngeal Cancer......Page 915
55. Cancer of the Larynx and Hypopharynx......Page 944
56. Management of Oropharyngeal Squamous Cell Carcinoma......Page 960
57. Cancer of the Oral Cavity......Page 992
58. Tumors of the Salivary Glands......Page 1017
59. Tumors of the Nose and Sinuses......Page 1046
VI THORACIC......Page 1047
60. Lung Cancer: Stage I and II......Page 1056
61. Lung Cancer: Stage III and IV......Page 1057
62. Pulmonary Metastasectomy......Page 1069
63. Chest Wall Tumors......Page 1096
64. Pleural Diseases: Primary and Metastatic Malignancies......Page 1109
65. Mediastinal Tumors......Page 1122
VI BREAST......Page 1123
66. Landmark Clinical Trials that Impacted Surgical Management of Invasive and Noninvasive Breast Cancer......Page 1134
67. Screening for Breast Cancer......Page 1152
68. Genetic and Familial Syndromes......Page 1172
69. Surgical Strategies for Breast Cancer Risk Reduction......Page 1183
70. Nonsurgical Strategies for Breast Cancer Risk Reduction......Page 1195
71. High-Risk Breast Pathology......Page 1206
72. Lobular Carcinoma in Situ and Lobular Neoplasia......Page 1218
73. Ductal Carcinoma in Situ......Page 1234
74. Unusual Breast Histologies......Page 1257
75. Breast Cancer Subtypes Identified by Gene Expression Profiles and Molecular Markers......Page 1270
76. Mastectomy and Breast Reconstruction......Page 1282
77. Breast Conserving Therapy for Breast Cancer......Page 1304
78. Management of the Clinically Negative Axilla in Patients with Invasive Breast Cancer......Page 1320
79. Management of the Pathologically Positive Axilla......Page 1334
80. Local Therapy in the Setting of Metastatic Disease......Page 1344
81. Radiation Therapy for High-Risk Breast Cancer......Page 1357
82. Overview of Systemic Therapy......Page 1386
83. Survivorship Issues in Breast Cancer......Page 1400
VII UPPER GASTROINTESTINAL......Page 1401
84. Epidemiology and Staging of Upper Gastrointestinal Cancer......Page 1415
85. Early Esophageal Cancer: Endoscopic Treatment Options......Page 1427
86. Transthoracic Esophagectomy......Page 1432
87. Transhiatal Esophagectomy......Page 1441
88. Minimally Invasive Esophagectomy for Esophageal Cancer: A Western Perspective......Page 1468
89. Multimodality Therapy for Esophageal Cancer: Eastern Experience......Page 1480
90. Multimodality Therapy for Esophageal Cancer: Western Experience Including Definitive Chemoradiation......Page 1494
91. Palliation of Incurable Esophageal Cancer......Page 1502
92. Esophagogastric Junction Cancer: Definition, Staging Aspects, and Therapeutic Implications......Page 1515
93. Surgical and Multimodality Treatments of Cancers at the Esophagogastric Junction: The Eastern Perspective......Page 1522
94. Special Operative and Multimodal Aspects of Esophago-Gastric Junction (EGJ) Cancer Care: Western Viewpoints......Page 1537
95. Early Gastric Cancer: Local, Endoscopic Options......Page 1548
96. Sentinel Node Navigation Surgery for Early Gastric Cancer......Page 1554
97. Mid-Stage Gastric Cancer: Surgical Resection Techniques......Page 1566
98. Minimally Invasive Surgical Resection for Mid-Stage Gastric Cancer......Page 1573
99. Multimodality Therapy of Gastric Cancer: Eastern Experience......Page 1585
100. Multimodality Therapy of Gastric Cancer: Western Experience......Page 1595
101. Palliation Of Incurable Gastric Cancer......Page 1608
102. Prophylactic Gastrectomy For Inherited Gastric Cancer......Page 1615
103. Duodenal Cancer (Including Intestinal Type Ampullary Cancer)......Page 1629
104. Tumors of the Small Bowel......Page 1649
IX LOWER GASTROINTESTINAL......Page 1650
105. Appendiceal Neoplasms......Page 1666
106. Colorectal Cancer: Molecular Biology and Inherited Cancer Syndromes......Page 1689
107. Locoregional Staging and Restaging of Rectal Cancer......Page 1705
108. Colectomy Approaches for Colorectal Cancer......Page 1744
109. Local Excision for Stage I Rectal Cancer......Page 1760
110. Total Mesorectal Excision for Rectal Cancer......Page 1777
111. Multimodality Treatment of Rectal Cancer......Page 1791
112. Adjuvant Therapy and Treatment of Systemic Disease for Colon Cancer......Page 1799
113. Treatment of Locally Advanced Colorectal Cancer......Page 1818
114. Recurrent Colorectal Cancer......Page 1840
115. Metastatic Colorectal Cancer......Page 1864
116. Anal Cancer......Page 1896
117. Rare GI Tumors......Page 1911
X GIST AND PERITONEUM......Page 1912
118. Gastrointestinal Stromal Tumors......Page 1938
119. Malignant Peritoneal Mesothelioma......Page 1951
120. Mucinous Appendiceal Tumors......Page 1967
121. Peritoneal Carcinomatosis from Colorectal Origin......Page 1980
122. Cytoreductive Surgery and Peritoneal-Based Therapies......Page 1995
XI HEPATOBILIARY......Page 1996
123. Radiological Imaging of Hepatobiliary and Pancreatic Tumors......Page 2027
124. Anatomic Considerations, Operative Techniques, and Perioperative Management of Hepatobiliary Malignancies......Page 2046
125. Minimally Invasive Techniques and Outcomes in Hepatic Resection......Page 2059
126. Interventional Radiology: Applications to Hepatobiliary Tumors......Page 2077
127. Hepatocellular Carcinoma......Page 2100
128. Colorectal Liver Metastases......Page 2117
129. Management of Hepatic Metastases from Neuroendocrine Tumors......Page 2132
130. Neuroendocrine Liver Metastases: Thermal Ablation, Transarterial Embolotherapy, and Future Directions......Page 2147
131. NonColorectal, NonNeuroendocrine Liver Metastases......Page 2167
132. Intrahepatic Cholangiocarcinoma......Page 2189
133. Perihilar Cholangiocarcinoma......Page 2224
134. Distal Cholangiocarcinoma and Periampullary Cancer......Page 2238
135. Gallbladder Cancer......Page 2262
136. Benign Liver Tumors......Page 2279
137. Cystic Lesions of the Liver and Biliary Tract......Page 2298
XII PANCREAS......Page 2299
138. Molecular Genetics of Pancreatic Neoplasms and Inherited Pancreatic Cancer Syndromes......Page 2308
139. Clinical and Pathologic Staging for Pancreatic Cancer......Page 2327
140. Multidisciplinary Management of Pancreatic Cancer......Page 2346
141. Pancreatic Cancer: Principles of Pancreaticoduodenectomy and Distal Pancreatectomy......Page 2363
142. Borderline Resectable Pancreatic Cancer and Techniques of Vascular Resection......Page 2381
143. Principles of Palliative Care for Patients with Pancreatic Adenocarcinoma......Page 2394
144. Treatment of Metastatic Pancreatic Cancer......Page 2417
145. Natural History and Principles of Management of Pancreatic Neuroendocrine Tumors......Page 2431
146. Pancreatic Neuroendocrine Tumors (PNET)......Page 2443
147. Systemic and Regional Therapy for Pancreatic Neuroendocrine Tumors......Page 2454
148. Mucinous Cystic Neoplasms of the Pancreas......Page 2474
149. Unusual Pancreatic Tumors......Page 2488
XIII RECONSTRUCTION......Page 2489
150. Principles and Overview of Oncoplastic Approaches in the Surgical Treatment of Breast Cancer......Page 2497
151. Oncoplastic Approaches to Partial Mastectomy......Page 2516
152. Oncoplastic Approach to Breast Cancer in Macromastia......Page 2527
153. Breast Reduction in the Surgical Management of Breast Cancer......Page 2543
154. Implant-Based Breast Reconstruction......Page 2563
155. Autologous Breast Reconstruction......Page 2586
156. Skin Reduction Mastectomy with Reconstruction......Page 2599
157. Chest Wall Reconstruction for Advanced/Recurrent Carcinoma of the Breast......Page 2607
158. Autologous Fat Grafting in Breast Reconstruction......Page 2621
159. Principles of Skin Grafting and Flaps......Page 2653
160. Dermal Substitutes in Oncologic Surgery......Page 2673
161. Skin Closure After Resection of Skin Malignancies, Including Melanoma......Page 2699
162. Head and Neck Reconstruction......Page 2732
163. Soft Tissue Reconstruction after Sarcoma Resection......Page 2745
164. Treatment of Postradiation Wounds......Page 2758
165. Management of Postradiation Chest Wall Defects......Page 2773
