A one-stop, comprehensive, and thoroughly updated resource for students, professors, and researchers alike
Thoroughly revised and updated, the Third Edition of Supramolecular Chemistry delivers a comprehensive and integrated approach to this rapidly evolving and quickly expanding field. Distinguished professors and authors Jonathan Steed and Jerry Atwood provide readers with a broad and exhaustive resource that assumes little in the way of prior knowledge of supramolecular chemistry.
Extensive new content on cutting edge research throughout the field including molecular machines and the mechanical bond, mechanochemistry, halogen bonding, and crystal nucleation accompanies full-color imagery and study problems designed to help students understand and apply the principles introduced within the book. Additional material is provided in the supplementary online resources, including solutions to the student exercises and PowerPoint slides of the figures in the book. Supramolecular Chemistry, Third Edition also includes:
The latest research and developments reported over the last decade
A unique “key references” system that highlights crucial reviews and primary literature
A description of key experimental techniques included in accessible “boxes” for the non-expert
Exercises and problems for students, complete with online solutions
Full-color illustrations and imagery designed to facilitate learning and retention of the key concepts and state-of-the art of the field
Perfect for undergraduate and postgraduate students taking courses on supramolecular chemistry, the Third Edition of Supramolecular Chemistry also belongs on the bookshelves of all researchers in this, and any closely related, fields. Academics, in particular postdoctoral students and professors, will benefit significantly from this text.
Author(s): Jonathan W. Steed, Jerry L. Atwood
Edition: 3
Publisher: Wiley
Year: 2022
Title Page
Copyright Page
About the Authors
Preface to the Third Edition
Acknowledgements
About the Front Cover
About the Companion Website
CHAPTER 1: Concepts
1.1 DEFINITION AND DEVELOPMENT OF SUPRAMOLECULAR CHEMISTRY
1.2 CLASSIFICATION OF SUPERMOLECULE FORMATION
1.3 RECEPTORS, COORDINATION, AND THE LOCK AND KEY ANALOGY
1.4 BINDING CONSTANTS
1.5 COOPERATIVITY, MULTIVALENCY, AND THE CHELATE EFFECT
1.6 PREORGANISATION AND COMPLEMENTARITY
1.7 THERMODYNAMIC AND KINETIC SELECTIVITY, AND DISCRIMINATION
1.8 NATURE OF SUPRAMOLECULAR INTERACTIONS
1.9 SOLVATION EFFECTS
1.10 SUPRAMOLECULAR CONCEPTS AND DESIGN
1.11 PRACTICAL APPLICATIONS OF SUPRAMOLECULAR CHEMISTRY
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 2: The Supramolecular Chemistry of Life
2.1 BIOLOGICAL INSPIRATION FOR SUPRAMOLECULAR CHEMISTRY
2.2 ALKALI METAL CATIONS IN BIOCHEMISTRY
2.3 PORPHYRINS AND TETRAPYRROLE MACROCYCLES
2.4 SUPRAMOLECULAR FEATURES OF PLANT PHOTOSYNTHESIS
2.5 UPTAKE AND TRANSPORT OF OXYGEN BY HAEMOGLOBIN
2.6 ENZYMES AND COENZYMES
2.7 SIGNALLING: NEUROTRANSMITTERS, HORMONES, AND PHEROMONES
2.8 DNA AND THE GENETIC CODE
2.9 BIOCHEMICAL SELF‐ASSEMBLY
2.10 BIOMINERALISATION
2.11 EMERGENCE OF LIFE
SUMMARY
REFERENCES
CHAPTER 3: Cation‐Binding Hosts
3.1 INTRODUCTION TO COORDINATION CHEMISTRY
3.2 PODANDS
3.3 THE CROWN AND LARIAT ETHERS
3.4 THE CRYPTANDS
3.5 THE SPHERANDS
3.6 NOMENCLATURE OF CATION‐BINDING MACROCYCLES
3.7 SELECTIVITY OF CATION COMPLEXATION
3.8 SOLUTION BEHAVIOUR AND APPLICATIONS OF CROWNS AND CRYPTANDS
3.9 MACROCYCLE SYNTHESIS: THE TEMPLATE EFFECT AND HIGH DILUTION
3.10 SOFT LIGANDS FOR SOFT METAL IONS
3.11 PROTON BINDING: THE SIMPLEST CATION
3.12 COMPLEXATION OF ORGANIC CATIONS
3.13 ALKALIDES AND ELECTRIDES
3.14 THE CALIXARENES
3.15 CARBON DONOR AND π‐ACID LIGANDS
3.16 THE SIDEROPHORES
SUMMARY
REFERENCES
CHAPTER 4: Anion Binding
4.1 INTRODUCTION
4.2 BIOLOGICAL ANION RECEPTORS
4.3 CONCEPTS IN ANION HOST DESIGN
4.4 CATIONIC RECEPTORS
4.5 NEUTRAL RECEPTORS
4.6 BORON BASED RECEPTORS AND LEWIS ACID CHELATES
4.7 METAL‐CONTAINING RECEPTORS
4.8 ANION‐BINDING HELICES
4.9 ANION TRANSPORT
SUMMARY
THOUGHT EXPERIMENTS
REFERENCES
CHAPTER 5: Ion‐Pair Receptors
5.1 SIMULTANEOUS ANION AND CATION BINDING
5.2 LABILE COORDINATION COMPLEXES AND CAGES AS ANION HOSTS
5.3 RECEPTORS FOR ZWITTERIONS
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 6: Molecular Guests in Solution
6.1 MOLECULAR HOSTS AND MOLECULAR GUESTS
6.2 INTRINSIC CURVATURE: GUEST BINDING BY CAVITANDS
6.3 CYCLODEXTRINS
6.4 MOLECULAR TWEEZERS, CLIPS AND CLEFTS
6.5 CYCLOPHANE HOSTS
6.6 CONSTRUCTING A SOLUTION HOST FROM CLATHRATE‐FORMING BUILDING BLOCKS: THE CRYPTOPHANES
6.7 COVALENT CAGES: CARCERANDS AND HEMICARCERANDS
6.8 COORDINATION CAGES
6.9 HALOGEN‐BONDED COMPLEXES
SUMMARY
STUDY PROBLEMS
THOUGHT EXPERIMENT
REFERENCES
CHAPTER 7: Solid‐State Inclusion Compounds
7.1 NOMENCLATURE AND THERMOCHEMICAL ASPECTS
7.2 POROSITY AND GAS SORPTION
7.3 CLATHRATE HYDRATES
7.4 UREA AND THIOUREA CLATHRATES
7.5 CHANNEL CLATHRATES
7.6 POLARITY FORMATION
7.7 HYDROQUINONE, PHENOL, DIANIN’S COMPOUND, AND THE HEXAHOST STRATEGY
7.8 MACROCYCLIC CLATHRATES
7.9 COVALENT CAGES
7.10 GAS SORPTION BY COORDINATION COMPLEX HOSTS
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 8: Crystal Engineering
8.1 CONCEPTS
8.2 CRYSTAL NUCLEATION AND GROWTH
8.3 UNDERSTANDING CRYSTAL STRUCTURES
8.4 THE CAMBRIDGE STRUCTURAL DATABASE
8.5 POLYMORPHISM
8.6 CO‐CRYSTALS
8.7 SOLID STATE TRANSFORMATIONS
8.8 CRYSTAL STRUCTURE PREDICTION
8.9 COMMON AND EXOTIC SUPRAMOLECULAR SYNTHONS
8.10 HALOGEN BONDING
8.11 BENDING AND JUMPING CRYSTALS
SUMMARY
STUDY PROBLEMS
THOUGHT EXPERIMENT
REFERENCES
CHAPTER 9: Network Solids
9.1 WHAT ARE NETWORK SOLIDS?
9.2 ZEOLITES
9.3 LAYERED SOLIDS AND INTERCALATES
9.4 IN THE BEGINNING: HOFFMAN INCLUSION COMPOUNDS AND WERNER CLATHRATES
9.5 COORDINATION POLYMERS
9.6 POROUS METAL–ORGANIC FRAMEWORKS
9.7 COVALENT ORGANIC FRAMEWORKS
SUMMARY
STUDY PROBLEM
REFERENCES
CHAPTER 10: Self‐Assembly
10.1 INTRODUCTION
10.2 PROTEINS AND FOLDAMERS: SINGLE‐MOLECULE SELF‐ASSEMBLY
10.3 BIOCHEMICAL SELF‐ASSEMBLY
10.4 SELF‐ASSEMBLY IN SYNTHETIC SYSTEMS: KINETIC AND THERMODYNAMIC CONSIDERATIONS
10.5 HELICATES AND HELICAL ASSEMBLIES
10.6 SELF‐ASSEMBLING COORDINATION COMPOUNDS
10.7 SELF‐ASSEMBLY OF CLOSED COMPLEXES BY HYDROGEN BONDING
10.8 TEMPLATED ASSEMBLY OF PORPHYRIN ARRAYS
10.9 PROGRAMMED ASSEMBLY WITH BIOMOLECULES
SUMMARY
STUDY PROBLEMS
THOUGHT EXPERIMENT
REFERENCES
CHAPTER 11: The Mechanical Bond
11.1 SCOPE AND IMPORTANCE OF MECHANICAL BONDING AND MECHANOSTEREOCHEMISTRY
11.2 CATENANES AND ROTAXANES
11.3 MOLECULAR KNOTS
11.4 BORROMEAN RINGS AND MULTIPLY INTERLOCKED CATENANES
11.5 INTERPENETRATED CAGES
11.6 AN UNUSUAL THRING
SUMMARY
STUDY PROBLEM
REFERENCES
CHAPTER 12: Molecular Devices and Machines
12.1 INTRODUCTION
12.2 SUPRAMOLECULAR PHOTOCHEMICAL DEVICES
12.3 INFORMATION AND SIGNALS: SEMIOCHEMISTRY AND SENSING
12.4 MOLECULE‐BASED ELECTRONICS
12.5 MOLECULAR ANALOGUES OF MECHANICAL MACHINES
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 13: Biological Mimics and Supramolecular Catalysis
13.1 INTRODUCTION
13.2 CYCLODEXTRINS AS ENZYME MIMICS
13.3 CORANDS AS ATPASE MIMICS
13.4 CATION‐BINDING HOSTS AS TRANSACYLASE MIMICS
13.5 METALLOBIOSITES
13.6 ENZYME MIMETIC MATERIALS
13.7 ION CHANNEL MIMICS
13.8 SUPRAMOLECULAR CATALYSIS
SUMMARY
THOUGHT EXPERIMENT
REFERENCES
CHAPTER 14: Interfaces and Liquid Assemblies
14.1 ORDER IN LIQUIDS
14.2 SURFACTANTS AND INTERFACIAL ORDERING
14.3 LIQUID CRYSTALS
14.4 POLYAMORPHOUS LIQUIDS
14.5 IONIC LIQUIDS AND DEEP EUTECTIC SOLVENTS
14.6 LIQUID CLATHRATES
14.7 POROUS LIQUIDS
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 15: Supramolecular Materials
15.1 INTRODUCTION
15.2 DENDRIMERS
15.3 FRACTAL ASSEMBLIES
15.4 COVALENT POLYMERS WITH SUPRAMOLECULAR PROPERTIES
15.5 SELF‐ASSEMBLED SUPRAMOLECULAR POLYMERS
15.6 MECHANICALLY INTERLOCKED MATERIALS
15.7 SUPRAMOLECULAR GELS
15.8 POLYMERIC LIQUID CRYSTALS
15.9 BIOLOGICAL SELF‐ASSEMBLED MATERIALS
SUMMARY
STUDY PROBLEMS
REFERENCES
CHAPTER 16: Dynamic Covalent Bonding and Complex Systems
16.1 CHEMISTRY OUT OF EQUILIBRIUM
16.2 DYNAMIC COMBINATORIAL LIBRARIES
16.3 SELF‐REPLICATION
16.4 SHAPESHIFTING MOLECULES
16.5 DISSIPATIVE SELF‐ASSEMBLY
SUMMARY
REFERENCES
CHAPTER17 Nanochemistry
17.1 WHEN IS NANO REALLY NANO?
17.2 NANOTECHNOLOGY: THE ‘TOP‐DOWN’ AND ‘BOTTOM‐UP’ APPROACHES
17.3 TEMPLATED AND BIOMIMETIC MORPHOSYNTHESIS
17.4 NANOSCALE PHOTONICS
17.5 MICROFABRICATION, NANOFABRICATION AND SOFT LITHOGRAPHY
17.6 ASSEMBLY AND MANIPULATION ON THE NANOSCALE
17.7 NANOPARTICLES
17.8 ENDOHEDRAL FULLERENES, NANOTUBES AND GRAPHENE
SUMMARY
THOUGHT EXPERIMENT
REFERENCES
Index
End User License Agreement
Copyright
Title Page
Dedication
Contents
Chapter 1: ‘I’m thinking’ – Oh, but are you?
Chapter 2: Renegade perception
Chapter 3: The Pushbacker sting
Chapter 4: ‘Covid’: The calculated catastrophe
Chapter 5: There is no ‘virus’
Chapter 6: Sequence of deceit
Chapter 7: War on your mind
Chapter 8: ‘Reframing’ insanity
Chapter 9: We must have it? So what is it?
Chapter 10: Human 2.0
Chapter 11: Who controls the Cult?
Chapter 12: Escaping Wetiko
Postscript
Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation
Bibliography
Index
Copyright
Title Page
Dedication
Contents
Chapter 1: ‘I’m thinking’ – Oh, but are you?
Chapter 2: Renegade perception
Chapter 3: The Pushbacker sting
Chapter 4: ‘Covid’: The calculated catastrophe
Chapter 5: There is no ‘virus’
Chapter 6: Sequence of deceit
Chapter 7: War on your mind
Chapter 8: ‘Reframing’ insanity
Chapter 9: We must have it? So what is it?
Chapter 10: Human 2.0
Chapter 11: Who controls the Cult?
Chapter 12: Escaping Wetiko
Postscript
Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation
Bibliography
Index
