Content: Low-molecular-weight organosulfur compounds in nature / Eric Block --
Chemical mechanisms of the cytochrome P-450 monooxygenase-catalyzed metabolism of phosphorothionate triesters / R.A. Neal --
Sulfur in propesticide action / T.R. Fukuto and M.A.H. Fahmy --
S-oxygenation in herbicide metabolism in mammals / D.H. Hutson --
Toxicological significance of oxidation and rearrangement reactions of S-chloroallyl thio- and dithiocarbamate herbicides / Ingolf Schuphan ... [et al.] --
Biological and chemical behavior of perhalogenmethylmercapto fungicides / Ingolf Schuphan ... [et al.] --
Comparative metabolism of dithiolane insecticides in plants, animals, and the environment / Chia C. Ku and Inder P. Kapoor --
Roles of iron-sulfur proteins in degradation of pesticidal chemicals by microorganisms / Fumio Matsumura, K. Yoneyama, and J. Marshall Clark --
Catabolism of glutathione conjugates of pesticides in higher plants / G.L Lamoureux and D.G. Rusness --
Role of gut microflora in metabolism of glutathione conjugates of xenobiotics / J.E. Bakke ... [et al.].
Author(s): Joseph D. Rosen, Philip S. Magee, and John E. Casida (Eds.)
Series: ACS Symposium Series 158
Publisher: American Chemical Society
Year: 1981
Language: English
Pages: 185
City: Washington, D.C
Title Page......Page 1
Half Title Page......Page 3
Copyright......Page 4
ACS Symposium Series......Page 5
FOREWORD......Page 6
PdftkEmptyString......Page 0
PREFACE......Page 7
1 Low-Molecular-Weight Organosulfur Compounds in Nature: The Search for New Pesticides......Page 9
Acyclic Sulfur Systems......Page 10
Heterocyclic Sulfur Systems......Page 14
Conclusion......Page 16
Literature Cited......Page 18
2 Chemical Mechanisms of the Cytochrome P-450 Monooxygenase-Catalyzed Metabolism of Phosphorothionate Triesters......Page 23
LITERATURE CITED......Page 37
3 Sulfur in Propesticide Action......Page 39
Derivatized Carbamates......Page 40
Aryl- and Alkylsulfenyl Methylcarbamates......Page 41
Ν,Ν'-Thiodicarbamates......Page 43
Dialkylaminosulfenylmethylcarbamates......Page 47
N-Sulfinylmethylcarbamates......Page 48
(Alkoxycarbonyl) (alkylamino)sulfenylphosphoramidothioates......Page 50
Literature Cited......Page 52
Alkylthiotriazines and Thiocarbamates......Page 54
In vitro studies on the S-oxygenating enzyme involved in cyanatryn metabolism......Page 60
Further Reactions of the S-oxides......Page 61
Literature Cited......Page 64
5 Toxicological Significance of Oxidation and Rearrangement Reactions of S-Chloroallyl Thio- and Dithiocarbamate Herbicides......Page 66
Thiocarbamate Sulfoxides......Page 67
Dithiocarbamate Sulfines......Page 72
Metabolism of Thio- and Dithiocarbamates......Page 75
Toxicological Significance of Oxidation and Rearrangement Reactions......Page 76
Summary......Page 81
Literature Cited......Page 82
6 Biological and Chemical Behavior of Perhalogenmethylmercapto Fungicides: Metabolism and in Vitro Reactions of Dichlofluanid in Comparison with Captan......Page 84
Metabolism of (fluorodichloro 14C-methyl)Dichlofluanid in Strawberries......Page 87
Metabolism of (trichloro- 14C-methyl) Captan in Spinach and Soil......Page 90
In Vitro Studies......Page 91
Mutagenicity Studies......Page 93
Literature Cited......Page 95
7 Comparative Metabolism of Dithiolane Insecticides in Plants, Animals, and the Environment......Page 96
Metabolism in Rats......Page 97
Metabolism in Plants......Page 100
Photodegradation Studies......Page 102
Metabolism in Fish in the Rice Paddy Environment......Page 105
Literature Cited......Page 108
Properties of Iron-sulfur Proteins Low Molecular Weight, Terminal Iron-Sulfur Proteins......Page 109
Iron-Sulfur Proteins as an Electron Transfer Component to Cytochrome Ρ-450......Page 111
Involvement of Iron-sulfur Proteins in Pesticide Degradation......Page 113
Metabolic Degradation of Toxaphene by Pseudomonas putida......Page 115
Effects of Added Cofactors on Toxaphene Metabolism by Washed Cells......Page 118
Degradation of Mexacarbate in Cell-free Extracts of Bacillus megaterium......Page 122
Literature Cited......Page 125
9 Catabolism of Glutathione Conjugates of Pesticides in Higher Plants......Page 128
Methods......Page 130
Results and Discussion......Page 131
Summary and Conclusions......Page 152
Glossary of Chemical Abbreviations......Page 156
Abstract......Page 157
Literature Cited......Page 158
10 Role of Gut Microflora in Metabolism of Glutathione Conjugates of Xenobiotics......Page 160
Catabolism Utilizing Microfloral C-S Lyases......Page 162
Catabolism Utilizing Tissue C-S Lyases And Microfloral S-Glucuronidases In Addition To The Microfloral C-S Lyase......Page 169
LITERATURE CITED......Page 171
C......Page 174
D......Page 176
G......Page 177
M......Page 178
P......Page 181
R......Page 183
T......Page 184
X......Page 185
