Content:
Advisory Board
Page ii
Edited by
Page iii
Copyright page
Page iv
List of Contributors
Pages xv-xxiv
Preface
Page xxv
Joseph F. Hoffman, Joseph F. Hoffman III
Acknowledgments
Page xxvii
Yale Membrane Transport Processes Volumes
Page xxix
Contents of Previous Volumes
Pages xxxi-xxxix
What is a Coupled Vectorial Process? Original Research Article
Pages 1-19
William P. Jencks
The Membrane Equilibrium with Chemical Reactions Original Research Article
Pages 21-51
Friedricha Sauer
Structural Aspects of Na.K-ATPase Original Research Article
Pages 53-65
Robertl Post
Detergent Solubilization of Na,K-ATPase Original Research Article
Pages 67-81
Mika Elesmann
Methods for the Cleavage of the Large Subunit of Na,K-ATPase and the Resolution of the Peptides Produced Original Research Article
Pages 83-102
Henry Rodriguez, Richard Harkins, Jack Kyte
Selective Purification of Na,K-ATPase and CA2+, Mg2+-ATPase from Eel Electroplax Original Research Article
Pages 103-106
L.M. Amende, S.P. Chock, Andr.W. Albers Nincds
High-Performance Gel Chromatography of Horse Kidney Na,K-ATPase Original Research Article
Pages 107-111
Makoto Nakao, Toshiko Nakao, Tomoko Ohno, Yuki Chihara, Masako Arai, Yoshihiro Fukushima
Native Membranes from Dog Kidney Outer Medulla, Enriched in Na,K-ATPase and Vesicular in Nature Original Research Article
Pages 113-118
Bliss Forbush III
Infrastructure of Na,K-ATPase in Plasma Membranes Vesicles Original Research Article
Pages 119-122
Elisabeth Skriver, Arvid B. Maunsbach, Peter Lethjørgensen
Electron Microscope Analysis of Two-Dimensional Crystals of Membrane-Bound Na,K-ATPase Original Research Article
Pages 123-126
Arvid B. Maunsbach, Elisabeth Skriver, Hans Herbert, Peter Lethj⊘rgensen
Organization of the Transmembrane Segments of Na,K-ATPase. Labeling of Lipid Embedded and Surface Domains of the a-Subunit and Its Tryptic Fragments with [125] lodonaphthylazide, [32P]ATP, and Photolabeled Ouabain Original Research Article
Pages 127-130
Peter Lethj⊘rgensen, Stephen J.D. Karlish, Carlos Gitler
Structural Studies on Lamb Kidney Na,K-ATPase Original Research Article
Pages 131-134
J.H. Collins, L.K. Lane, E. Ling, A. Schwartz, A. (Reeves)Zot, B. Forbushiii
Two Slightly Different α-Subunit Components of Kidney Na,K-ATPase Induced by Heat Treatment Original Research Article
Pages 135-138
T. Ohta, M. Kawamura, T. Hasegawa, H. Ishikura, K. Nagano
Radiation Inactivation Analysis of Na,K-ATPase Original Research Article
Pages 139-143
Paul Ottolenghi, J. Cliveellory, Roger A. Klein
Stoichiometrical Binding of Ligands to Less than 160 KilodaltonsofNa.K-ATPase Original Research Article
Pages 145-148
H. Matsui, Y. Hayashi, H. Homareda, M. Taguchi
The Active Site Structure of Na,K-ATPase: Location of a Specific Fluorescein Isothiocyanate-Reactive Site Original Research Article
Pages 149-151
Cynthia T. Carilli, Robert A. Farley, Lewis Cantley
Subunit Distribution of Sulfhydryl Groups and Disulfide Bonds in Renal Na,K-ATPase Original Research Article
Pages 153-155
M. Kawamura, T. Ohta, K. Nagano
Lipid Regions of Na,K-ATPase Examined with Fluorescent Lipid Probes Original Research Article
Pages 157-161
Kimberly A. Muczynski, Ward E. Harris, William L. Stahl
Role of Cholesterol and Other Neutral Lipids in Na,K-ATPase Original Research Article
Pages 163-166
J.J.H.H. M. Depont, W.H.M. Peters, S.L. Bonting
Cardiotonic Steroid Binding to Na,K-ATPase Original Research Article
Pages 167-201
Buss Forbush III
Binding of Monovalent Cations to the Na,K-ATPase Original Research Article
Pages 203-217
M. Yamaguchi, J. Sakamoto, Y. Tonomura
Half-of-the-Sites Reactivity of Na,K-ATPase Examined by the Accessibility of Vanadate and ATP into Enzyme-Ouabain Complexes Original Research Article
Pages 219-222
Otto Hansen
Binding of Rb+ and ADP to a Potassium-Like Form of Na,K-ATPase Original Research Article
Pages 223-227
J⊘rgen Jensen, Paul Ottolenghi
Side-Dependent Ion Effects on the Rate of Ouabain Binding to Reconstituted Human Red Cell Ghosts Original Research Article
Pages 229-233
H.H. Bodemann, H. Reichmann, T.J. Callahanandj, F. Hoffman
Intracellular Sodium Enhancement of Ouabain Binding to Na,K-ATPase and the Development of Glycoside Actions Original Research Article
Pages 235-239
Taia Kera, Kyosuke Temma, Satoshi Yamamoto
Lithium-Catalyzed Ouabain Binding to Canine Kidney Na,K-ATPase Original Research Article
Pages 241-245
George R. Henderson
Ouabain Binding and Na,K-ATPase in Released Human Red Cell Ghosts Original Research Article
Pages 247-250
D.G. Shoemaker, P.K. Lauf
Stereoelectronic Interaction between Cardiotonic Steroids and Na, K-ATPase: Molecular Mechanism of Digitalis Action Original Research Article
Pages 251-255
F. Dittrich, P. Berlin, K. Köpke, K.R.H. Repke
Use of Prophet and MMS-X Computer Graphics in the Study of the Cardiac Steroid Receptor Site of Na,K-ATPase Original Research Article
Pages 257-264
Dwight S. Fullerton, Eitaroki Tatsuji, Tamboue Deffo, Douglas C. Rohrer, Khalil Ahmed, Arthur H.L. From
Photoaffinity Labeling of the Ouabain Binding Site of Na.K-ATPase Original Research Article
Pages 265-270
Clifford C. Hall, Arnold E. Ruoho
New Ouabain Derivatives to Covalently Label the Digitalis Binding Site Original Research Article
Pages 271-276
Bernard Rossi, Gilles Ponzio, Michel Lazdunski, Maurice Goeldner, Christian Hirth
Ouabain Sensitivity: Diversity and Disparities Original Research Article
Pages 277-280
John S. Willis, J. Cuveellory
Ligand Interactions with the Substrate Site of Na,K-ATPase: Nucleotides, Vanadate, and Phosphorylation Original Research Article
Pages 281-314
Jens G. N⊘rby
Conformational Changes of Na,K-ATPase Necessary for Transport Original Research Article
Pages 315-322
Lewis C. Cantley, Cynthia T. Carilli, Roderic L. Smith, David Perlman
On the Mechanism Behind the Ability of Na,K-ATPase to Discriminate between Na+and K+ Original Research Article
Pages 323-341
Jens Chr. Skou
Characteristics of the Electric Eel Na,K-ATPase Phosphoprotein Original Research Article
Pages 343-347
Atsunobu Yoda, Shizuko Yoda
Sulfhydryl Groups of Na.K-ATPase: Effects of N-Ethylmaleimide on Phosphorylation from ATP in the Presence of Na+ + Mg2+ Original Research Article
Pages 349-352
Mikael Esmann, Irena Klodos
Alternative Pathways of Phosphorylation of Na,K-ATPase Regulated by Na+ Ions on Both Sides of the Plasma Membrane Original Research Article
Pages 353-354
Horst Walter
Structurally Different Nucleotide Binding Sites in Na,K-ATPase Original Research Article
Pages 355-359
Hermann Koepsell, Doris Ollig
Study of Na,K-ATPase with ATP Analogs Original Research Article
Pages 361-366
Wilhelm Schoner, Hartmut Pauls, Engin H. Serpersu, Gerold Rempeters, Rosemarie Patzelt-Wenczler, Marion Hasselberg
Affinity Labeling Studies of the ATP Binding Site of Canine Kidney Na,K-ATPase Original Research Article
Pages 367-370
James B. Cooper, Carl Johnson, Charles G. Winter
31P[180] NMR Kinetic Analysis of 180 Exchange Reaction between P, and H20 Catalyzed by Na,K-ATPase Original Research Article
Pages 371-375
A. Stephen Dahms, Joelle E. Miara
Principal Conformations of the α-Subunit and Ion Translocation Original Research Article
Pages 377-401
Peter L. J⊘rgensen
Magnesium-Induced Conformational Changes in Na,K-ATPase Original Research Article
Pages 403-424
S.L. Bonting, H.G.P. Swarts, W.H.M. Peters, F.M.A.H. Schuurmans Stekhoven, J.J.H.H.M. Depont
Rubidium Movements in Vesicles Reconstituted with Na,K-ATPase, Measured in the Absence of ATP and Pi, in the Presence of Either Ligand, and in the Presence of Both Ligands: Role of the “Occluded Staté in Allowing for the Control of the Direction of Ion Movements 5. Original Research Article
Pages 425-449
J.D. Karlish, W.D. Stein
Eosin: A Fluorescent Probe of ATP Binding to Na,K-ATPase Original Research Article
Pages 451-455
J.C. Skou, M. Esmann
Interaction of Divalent Cations with Fluorescein-Labeled Na,K-ATPase Original Research Article
Pages 457-463
Marcia Steinberg, James G. Kapakos, Parimal C. Sen
Cation Activation of Na,K-ATPase after Treatment with Thimerosal Original Research Article
Pages 465-469
Manisha D. Mone, Jack H. Kaplan
Alteration of Conformational Equilibria in Na,K-ATPase by Glutaraldehyde Treatment Original Research Article
Pages 471-476
David M. Chipman, E. Elhanany, R. Berger, A. Lev
Conformational Transition between ADP-Sensitive Phosphoenzyme and Potassium-Sensitive Phosphoenzyme Original Research Article
Pages 477-480
Kazuya Taniguchi, Kuniaki Suzuki, Shoichi Iida
Relation between Red Cell Membrane Na,K-ATPase and Band 3 Original Research Article
Pages 481-484
Eric T. Fosselanda, K. Solomon
Kinetic Analyses and the Reaction Mechanism of the Na,K-ATPase Original Research Article
Pages 485-512
Joseph D. Robinson
Evidence for Parallel Pathways of Phosphoenzyme Formation in the Mechanism of ATP Hydrolysis by Electrophorus Na,K-ATPase Original Research Article
Pages 513-535
Jeffrey P. Froehuch, Ann S. Hobbs, R. Wayne Albers
Evaluation of the Reaction Mechanism of the Sodium Pump by Steady-State Kinetics Original Research Article
Pages 537-546
John R. Sachs
Kinetic Evidence in Favor of a Consecutive Model of the Sodium Pump Original Research Article
Pages 547-551
D.A. Eisner, D.E. Richards
Kinetic Models of Na-Dependent Phosphorylation of Na,K-ATPase from Rat Brain Original Research Article
Pages 553-556
Donald M. Foster, Stanley J. Russell, Khalil Ahmed
Reinvestigation of the Sequence of Sensitivity of Phosphoenzyme of Na,K-ATPase to ADP and K+ during Presteady State of the Phosphorylation by ATP Original Research Article
Pages 557-560
Y. Fukushima, M. Nakao
Interaction of Na+,K+ and ATP with Na,K-ATPase Original Research Article
Pages 561-564
P.J. Garrahan, R. Rossi, A.F. Rega
Sodium Ion Discharge From Pig Kidney Na,K-ATPase Original Research Article
Pages 565-568
Yuki Chihara, Makoto Nakao
ADP Sensitivity of the Native and Oligomycin-Treated Na,K-ATPase Original Research Article
Pages 569-572
Ann S. Hobbs, R. Waynealbers, Jeffrey P. Froehlich
Three (at Least) Consecutive Phosphointermediates of Na-ATPase Original Research Article
Pages 573-576
I. Klodos, J.G. N⊘rby, N.O. Christiansen
Aspects of the Presteady State Hydrolysis of ATP by Na,K-ATPase Original Research Article
Pages 577-580
A.G. Lowe, L.A. Reeve
Identity of the Na Activation Sites in ATPase with the K Activation Sites in p-Nitrophenylphosphatase Original Research Article
Pages 581-585
L.A. Parodi, J.F. Pincus, L. Josephson, D.J. Sorce, S.R. Simon
On the Existence of Two Distinct Hydrolysis Cycles for Na,K-ATPase with Only One Active Substrate Site Original Research Article
Pages 587-590
Igor W. Plesner
Kinetic Analysis of the Effects of Na+ and K+ on Na,K-ATPase Original Research Article
Pages 591-594
Liselotte Plesner, Igor W. Plesner
Divalent Cations and Conformational States of Na,K-ATPase Original Research Article
Pages 595-598
Joseph D. Robinson
Na,K-ATPase: Reaction Mechanisms and Ion Translocating Steps Original Research Article
Pages 599-623
Paul Deweer
Existence and Role of Occluded-lon Forms of Na,K-ATPase Original Research Article
Pages 625-638
I.M. Glynn, D.E. Richards
Na and K Fluxes Mediated by ATP-Free and ATP-Activated Na,K-ATPase in Liposomes Original Research Article
Pages 639-642
Beatricem Anner
Sidedness of Cations and ATP Interactions with the Sodium Pump Original Research Article
Pages 643-647
L. Beaugé, R. Dipolo
Sidedness of Sodium Interactions with the Sodium Pump in the Absence of K+ Original Research Article
Pages 649-652
Rhona Blostein
Magnesium Dependence of Sodium Pump Mediated Sodium Transport in Intact Human Red Cells Original Research Article
Pages 653-657
P.W. Flatman, V.L. Lew
K+-lndependent Active Transport of Na+ by Na,K-ATPase Original Research Article
Pages 659-663
Michael Forgac, Gilbert Chin
ADP-ATP Exchange in Internally Dialyzed Squid Giant Axons Original Research Article
Pages 665-669
Paulde Weer, Gerda E. Breitwieser, H. Gilbert Smith, Brian G. Kennedy
Sodium Pump-Catalyzed ATP-ADP Exchange in Red Blood Cells: The Effects of Intracellular and Extracellular Na and K Ions Original Research Article
Pages 671-675
Jack H. Kaplan
Ouabain-Sensitive ATP-ADP Exchange and Na-ATPase of Resealed Red Cell Ghosts Original Research Article
Pages 677-681
J.D. Cavieres
Effect of Internal Adenine Nucleotides on Sodium Pump-Catalyzed Na-Na and Na-K Exchanges Original Research Article
Pages 683-686
Brian G. Kennedy, Gorm Lunn, Joseph F. Hoffman
Na/K Pump in Inside-Out Vesicles Utilizing ATP Synthesized at the Membrane Original Research Article
Pages 687-691
Robert W. Mercer, Beverley E. Farquharson, Philip B. Dunham
Anion-Coupled Na Efflux Mediated by the Na/K Pump in Human Red Blood Cells Original Research Article
Pages 693-695
S. Dissing, Joseph F. Hoffman
Effect of Trypsin Digestion on the Kinetic Behavior of the Na/K Pump in Intact Erythrocytes Original Research Article
Pages 697-701
Donna L. Kropp
Sodium Movement and ATP Hydrolysis in Basolateral Plasma Membrane Vesicles from Proximal Tubular Cells of Rat Kidney Original Research Article
Pages 703-706
F. Proverbio, T. Proverbio, R. Marin
Stoichiometry of the Electrogenic Na Pump in Barnacle Muscle: Simultaneous Measurement of Na Efflux and Membrane Current Original Research Article
Pages 707-711
M.T. Nelson, W.J. Lederer
Regulation of Na,K-ATPase by Its Biosynthesis and Turnover Original Research Article
Pages 713-751
Norman J. Karin, John S. Cook
Biosynthesis of the Na,K-ATPase in MDCK Cells Original Research Article
Pages 753-764
J. Sherman, T. Morimoto, D.D. Sabatini
Possible Functional Differences between the Two Na,K-ATPases of the Brain Original Research Article
Pages 765-780
Kathleen J. Sweadner
Antigenic Properties of the α-, β-, and γ-Subunits of Na,K-ATPase Original Research Article
Pages 781-785
William Ball Jr., John H. Collins, Lois Land, Arnold Schwartz
Antibodies to Na,K-ATPase: Characterization and Use in Cell-Free Synthesis Studies Original Research Article
Pages 787-789
Alicia McDonough, Andrew Hiatt, Isidore Edelman
Immunoreactivity of the α-and α(+)-Subunits of Na,K-ATPase in Different Organs and Species Original Research Article
Pages 791-795
Gerard D. Schellenberg, Irene V. Pech, William L. Stahl
Role of Na+ andCa2+ Fluxes in Terminal Differentiation of Murine Erythroleukemia Cells Original Research Article
Pages 797-802
I.G. Macara, R.D. Smith, L.C. Cantley
Na/K Pumps and Passive K+ Transport in Large and Small Reticulocytes of Anemic Low- and High-Potassium Sheep Original Research Article
Pages 803-808
P.K. Law, G. Valet
Enhancement of Biosynthesis of Na,K-ATPase in the Toad Urinary Bladder by Aldosterone but Not T3 Original Research Article
Pages 809-812
K. Geering, M. Girardet, C. Bron, J.-P. Kraehenbühl, B.C. Rossier
Na,K-ATPase Activity in Rat Nephron Segments: Effect of Low Potassium Diet and Thyroid Deficiency Original Research Article
Pages 813-817
Lal C. Garg, C. Craig Tisher
