First published over twenty years ago, "Stockley's Drug Interactions" is still the most indispensable and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed yet concise monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management. Individual interactions are assembled alphabetically into chapters, grouped therapeutically, pharmacologically or individually. Both Recommended International Nonproprietary Names (rINN) and US Adopted Names (USAN) are used throughout the book.
Author(s): Karen Baxter
Edition: 8th ed
Publisher: Pharmaceutical Press
Year: 2008
Language: English
Pages: 1473
City: London; Chicago
Cover
......Page 1
Contents......Page 5
Preface......Page 6
Abbreviations......Page 7
Before using this book . . .......Page 8
B. What is the incidence of drug interactions?......Page 10
D. Mechanisms of drug interaction......Page 11
1.2. Drug distribution interactions......Page 12
1.3. Drug metabolism (biotransformation) interactions......Page 13
1.4. Drug excretion interactions......Page 16
1.5. Drug transporter proteins......Page 17
2.2. Antagonistic or opposing interactions......Page 18
E. Drug-herb interactions......Page 19
G. Conclusions......Page 20
2: ACE inhibitors and Angiotensin II receptor antagonists......Page 21
ACE inhibitors + Antacids......Page 22
ACE inhibitors + Aspirin......Page 23
ACE inhibitors + Calcium-channel blockers......Page 27
ACE inhibitors + Colloids......Page 28
ACE inhibitors + Dialysis or Transfusion membranes......Page 29
ACE inhibitors + Diuretics; Loop, Thiazide and related......Page 30
ACE inhibitors + Diuretics; Potassium-sparing......Page 32
ACE inhibitors + Dopamine agonists......Page 33
ACE inhibitors and Angiotensin II receptor antagonists + Epoetin......Page 34
ACE inhibitors + Gold......Page 35
ACE inhibitors + Insect allergen extracts......Page 36
ACE inhibitors + NSAIDs......Page 37
ACE inhibitors and other antihypertensives + Orlistat......Page 40
ACE inhibitors + Probenecid......Page 41
Angiotensin II receptor antagonists + Antacids......Page 42
Angiotensin II receptor antagonists + Aspirin or NSAIDs......Page 43
Angiotensin II receptor antagonists + Calcium-channel blockers......Page 44
Angiotensin II receptor antagonists + Diuretics; Potassium-sparing......Page 45
Angiotensin II receptor antagonists + H2-receptor antagonists......Page 46
Angiotensin II receptor antagonists; Losartan + Erythromycin......Page 47
Angiotensin II receptor antagonists; Losartan + Phenytoin......Page 48
3: Alcohol......Page 49
Alcohol + Amisulpride......Page 51
Alcohol + Antibacterials; Ciprofloxacin......Page 52
Alcohol + Antibacterials; Metronidazole......Page 53
Alcohol + Antibacterials; Tetracyclines......Page 54
Alcohol + Antiepileptics; Carbamazepine......Page 55
Alcohol + Antihistamines......Page 56
Alcohol + Antihypertensives......Page 57
Alcohol + Antimycobacterials......Page 58
Alcohol + Antipsychotics......Page 59
Alcohol + Aspirin......Page 60
Alcohol + Barbiturates......Page 61
Alcohol + Benzodiazepines and related drugs......Page 62
Alcohol + Bupropion......Page 64
Alcohol + Caffeine......Page 65
Alcohol + Cannabis......Page 66
Alcohol + Clomethiazole......Page 67
Alcohol + Cocaine......Page 68
Alcohol + Disopyramide......Page 69
Alcohol + Disulfiram......Page 70
Alcohol + Edible fungi......Page 71
Alcohol + Furazolidone......Page 72
Alcohol + H2-receptor antagonists......Page 73
Alcohol + Herbal medicines; Ginseng......Page 74
Alcohol + Hormonal contraceptives......Page 75
Alcohol + Ivermectin......Page 76
Alcohol + Meprobamate......Page 77
Alcohol + Methylphenidate......Page 78
Alcohol + Nicotine......Page 79
Alcohol + NSAIDs......Page 80
Alcohol + Opioids......Page 81
Alcohol + Paracetamol (Acetaminophen)......Page 82
Alcohol + Phosphodiesterase type-5 inhibitors......Page 83
Alcohol + Proton pump inhibitors......Page 84
Alcohol + Sibutramine......Page 85
Alcohol + SSRIs......Page 86
Alcohol + Tacrolimus or Pimecrolimus......Page 87
Alcohol + Trazodone......Page 88
Alcohol + Tricyclic antidepressants......Page 89
Alcohol + Vitamin A (Retinol)......Page 90
Alcohol + Xylene......Page 91
4: Alpha blockers......Page 92
Alpha blockers + Beta blockers......Page 93
Alpha blockers + Calcium-channel blockers......Page 94
Alpha blockers + Diuretics......Page 95
Alpha blockers + NSAIDs......Page 96
Bunazosin + Rifampicin (Rifampin)......Page 97
Indoramin + MAOIs......Page 98
5: Anaesthetics and Neuromuscular blockers......Page 99
Anaesthetics, general + Anaesthetics, local......Page 101
Anaesthetics, general + Anticholinesterases......Page 102
Anaesthetics, general + Antihypertensives......Page 103
Anaesthetics, general + Baclofen......Page 104
Anaesthetics, general + Beta-agonist bronchodilators......Page 105
Anaesthetics, general + Beta blockers......Page 106
Anaesthetics, general + Herbal medicines......Page 107
Anaesthetics, general + Inotropes and Vasopressors......Page 108
Anaesthetics, general + MAOIs......Page 109
Anaesthetics, general + Neuromuscular blockers......Page 110
Anaesthetics, general + Opioids......Page 112
Anaesthetics, general + Phenytoin, Phenobarbital or Rifampicin (Rifampin)......Page 113
Anaesthetics, general and/or Neuromuscular blockers + Theophylline......Page 114
Anaesthetics, general and/or Neuromuscular blockers + Tricyclic and related antidepressants......Page 115
Anaesthetics, local + Alcohol and/or Antirheumatics......Page 116
Anaesthetics, local + Antihypertensives......Page 117
Anaesthetics, local + Benzodiazepines......Page 118
Anaesthetics, local + Fluvoxamine......Page 119
Anaesthetics, local + Ondansetron......Page 120
Botulinum toxin + Miscellaneous......Page 121
Neuromuscular blockers + Aminoglycosides......Page 122
Neuromuscular blockers + Anticholinesterases......Page 123
Neuromuscular blockers + Antiepileptics......Page 124
Neuromuscular blockers + Antineoplastics......Page 125
Neuromuscular blockers + Aprotinin......Page 126
Neuromuscular blockers + Beta-agonist bronchodilators......Page 127
Neuromuscular blockers + Bretylium......Page 128
Neuromuscular blockers + Chloroquine or Quinine......Page 129
Neuromuscular blockers + Corticosteroids......Page 130
Neuromuscular blockers + Ecothiopate iodide......Page 131
Neuromuscular blockers + H2-receptor antagonists......Page 132
Neuromuscular blockers + Immunosuppressants......Page 133
Neuromuscular blockers + Magnesium compounds......Page 134
Neuromuscular blockers + MAOIs......Page 135
Neuromuscular blockers + Miscellaneous anti-infectives......Page 136
Neuromuscular blockers + Neuromuscular blockers......Page 137
Neuromuscular blockers + Organophosphorus compounds......Page 139
Neuromuscular blockers + Tobacco......Page 140
Neuromuscular blockers + Ulinastatin......Page 141
6: Analgesics and NSAIDs......Page 142
Aspirin or other Salicylates + Carbonic anhydrase inhibitors......Page 144
Aspirin + Food......Page 145
Aspirin + Phenylbutazone......Page 146
Nefopam + Miscellaneous......Page 147
NSAIDs; Coxibs + Antacids......Page 148
NSAIDs; Ibuprofen and related drugs + Antacids......Page 149
NSAIDs; Indometacin or Sulindac + Antacids......Page 150
NSAIDs + Aspirin; Anti-inflammatory dose......Page 151
NSAIDs + Aspirin; Antiplatelet dose......Page 153
NSAIDs + Azoles......Page 154
NSAIDs or Aspirin + Caffeine......Page 155
NSAIDs + Food......Page 156
NSAIDs or Aspirin + Gold......Page 157
NSAIDs or Aspirin + H2-receptor antagonists......Page 158
NSAIDs or Salicylates + Mazindol......Page 159
NSAIDs + NSAIDs......Page 160
NSAIDs or Aspirin + Paracetamol (Acetaminophen)......Page 161
NSAIDs + Probenecid......Page 162
NSAIDs or Aspirin + Prostaglandins......Page 163
NSAIDs or Aspirin + Proton pump inhibitors......Page 164
NSAIDs or Aspirin + SSRIs......Page 165
NSAIDs + Tobacco......Page 166
NSAIDs; Diclofenac topical + Miscellaneous......Page 167
NSAIDs; Naproxen + Sulglicotide......Page 168
NSAIDs; Sulindac + Dimethyl sulfoxide (DMSO)......Page 169
Opioids + Antiemetics; Ondansetron......Page 170
Opioids + Antiepileptics; Enzyme-inducing......Page 171
Opioids + Antihistamines......Page 172
Opioids; Fentanyl and related drugs + Azoles......Page 173
Opioids + Barbiturates......Page 174
Opioids + Benzodiazepines......Page 175
Opioids; Fentanyl and related drugs + Benzodiazepines......Page 176
Opioids + Cannabis......Page 177
Opioids + Food......Page 178
Opioids + Grapefruit juice......Page 179
Opioids + H2-receptor antagonists......Page 180
Opioids + Hormonal contraceptives......Page 181
Opioids + Local anaesthetics......Page 182
Opioids; Fentanyl and related drugs + Macrolides......Page 183
Opioids + NRTIs......Page 184
Opioids; Methadone + NNRTIs......Page 185
Opioids + NSAIDs......Page 186
Opioids + Opioids......Page 188
Opioids + Protease inhibitors......Page 189
Opioids; Fentanyl and related drugs + Protease inhibitors......Page 190
Opioids; Methadone + Protease inhibitors......Page 191
Opioids + Quinidine......Page 192
Opioids; Codeine and related drugs + Quinidine......Page 193
Opioids; Methadone + Rifamycins......Page 194
Opioids + Tobacco......Page 195
Opioids + Tricyclic and related antidepressants......Page 196
Opioids; Alfentanil + Reserpine......Page 197
Opioids; Methadone + Ciprofloxacin......Page 198
Paracetamol (Acetaminophen) + Amantadine......Page 199
Paracetamol (Acetaminophen) + Antiepileptics......Page 200
Paracetamol (Acetaminophen) + Colestyramine......Page 201
Paracetamol (Acetaminophen) + Food......Page 202
Paracetamol (Acetaminophen) + H2-receptor antagonists......Page 203
Paracetamol (Acetaminophen) + Isoniazid......Page 204
Paracetamol (Acetaminophen) + Opioids......Page 205
Paracetamol (Acetaminophen) + Rifampicin (Rifampin)......Page 206
Paracetamol (Acetaminophen) + Tobacco......Page 207
7: Anorectics and Stimulants......Page 208
Amfetamines + Phenylpropanolamine......Page 209
Amfetamines and related drugs + SSRIs......Page 210
Atomoxetine + CYP2D6 inhibitors......Page 211
Dexfenfluramine or Fenfluramine + Other anorectics......Page 212
Modafinil + Miscellaneous......Page 213
Sibutramine + Azoles......Page 214
Sibutramine + SSRIs......Page 215
8: Anthelmintics, Antifungals and Antiprotozoals......Page 216
Albendazole + Corticosteroids......Page 218
Albendazole + Praziquantel......Page 219
Amphotericin B + Azoles......Page 220
Amphotericin B; Oral + Sucralfate......Page 221
Atovaquone + Miscellaneous......Page 222
Atovaquone + Tetracyclines......Page 223
Azoles + Cola drinks......Page 224
Azoles + Food......Page 225
Azoles + H2-receptor antagonists......Page 226
Azoles + Proton pump inhibitors......Page 227
Azoles + Rifabutin......Page 228
Azoles + Rifampicin (Rifampin) and/or Isoniazid......Page 229
Azoles; Itraconazole + Grapefruit and other fruit juices......Page 230
Chloroquine or Hydroxychloroquine + Antacids or Kaolin......Page 231
Chloroquine + Promethazine......Page 232
Co-artemether + Mefloquine......Page 233
Echinocandins + Azoles......Page 234
Echinocandins + Rifampicin (Rifampin) and other enzyme inducers......Page 235
Flucytosine + Cytarabine......Page 236
Griseofulvin + Phenobarbital......Page 237
Halofantrine + Miscellaneous......Page 238
Ivermectin + Levamisole......Page 239
Mefloquine + Artemisinin derivatives......Page 240
Mefloquine + Metoclopramide......Page 241
Mefloquine + Quinolones......Page 242
Mefloquine + Typhoid vaccine; Oral......Page 243
Praziquantel + Chloroquine......Page 244
Praziquantel + Food......Page 245
Proguanil + Chloroquine......Page 246
Pyrantel + Piperazine......Page 247
Quinine + Colestyramine......Page 248
Quinine + Miscellaneous......Page 249
Quinine + Tobacco......Page 250
Terbinafine + Rifampicin (Rifampin)......Page 251
9: Antiarrhythmics......Page 252
Adenosine + Xanthines......Page 253
Amiodarone + Anaesthesia......Page 254
Amiodarone + Beta blockers......Page 255
Amiodarone + Colestyramine......Page 256
Amiodarone + Macrolides......Page 257
Amiodarone + Quinolones......Page 258
Azimilide + Miscellaneous......Page 259
Cibenzoline (Cifenline) + H2-receptor antagonists......Page 260
Disopyramide + Macrolides......Page 261
Disopyramide + Phenytoin......Page 262
Dofetilide + Antacids......Page 263
Dofetilide + Miscellaneous......Page 264
Dofetilide + Verapamil......Page 265
Drugs that prolong the QT interval + Other drugs that prolong the QT interval......Page 266
Flecainide + Antacids or Food......Page 267
Flecainide + Quinidine or Quinine......Page 268
Flecainide + Urinary acidifiers or alkalinisers......Page 269
Ibutilide + Class Ic antiarrhythmics......Page 270
Lidocaine + Barbiturates......Page 271
Lidocaine + Dextromethorphan......Page 272
Lidocaine + H2-receptor antagonists......Page 273
Lidocaine + Mexiletine......Page 274
Lidocaine + Propafenone......Page 275
Mexiletine + Antacids, Atropine or Metoclopramide......Page 276
Mexiletine + Opioids......Page 277
Mexiletine + SSRIs......Page 278
Moracizine + Propranolol......Page 279
Procainamide + Beta blockers......Page 280
Procainamide + Quinidine......Page 281
Procainamide + Trimethoprim......Page 282
Propafenone + Ketoconazole......Page 283
Propafenone + SSRIs......Page 284
Quinidine + Amiodarone......Page 285
Quinidine + Antiepileptics......Page 286
Quinidine + Calcium-channel blockers......Page 287
Quinidine + Disulfiram......Page 288
Quinidine + Grapefruit juice......Page 289
Quinidine + Ketoconazole......Page 290
Quinidine + Quinolones......Page 291
Tocainide + H 2-receptor antagonists......Page 292
Tocainide + Rifampicin (Rifampin)......Page 293
10: Antibacterials......Page 294
Aminoglycosides + Cephalosporins......Page 295
Aminoglycosides + Loop diuretics......Page 296
Aminoglycosides + Miconazole......Page 297
Aminoglycosides + Penicillins or Carbapenems......Page 298
Aminoglycosides + Polygeline (Haemaccel)......Page 299
Aminosalicylic acid + Diphenhydramine......Page 300
Cephalosporins + Antacids......Page 301
Cephalosporins + Food......Page 302
Cephalosporins + Furosemide......Page 303
Cephalosporins + H2-receptor antagonists......Page 304
Cephalosporins; Cefotaxime + Penicillins......Page 305
Cephalosporins; Ceftazidime + Indometacin......Page 307
Chloramphenicol + Other antibacterials......Page 308
Clindamycin or Lincomycin + Food or Drinks......Page 309
Co-trimoxazole + Kaolin-pectin......Page 310
Co-trimoxazole + Salbutamol (Albuterol)......Page 311
Dapsone + Clofazimine......Page 312
Dapsone + Proguanil......Page 313
Dapsone + Trimethoprim......Page 314
Ethambutol + Antacids......Page 315
Isoniazid + Antacids......Page 316
Isoniazid + Ethambutol......Page 317
Isoniazid + H2-receptor antagonists......Page 318
Isoniazid + Rifamycins......Page 319
Linezolid + Antidepressants......Page 320
Linezolid + Food......Page 321
Linezolid + Sympathomimetics......Page 322
Macrolides + Azoles......Page 323
Macrolides + H2-receptor antagonists......Page 324
Macrolides + Rifamycins......Page 325
Macrolides; Clarithromycin + Disulfiram......Page 326
Kaolin-pectin......Page 327
Metronidazole + Diosmin......Page 328
Metronidazole + Sucralfate......Page 329
Nitrofurantoin + Azoles......Page 330
Penicillins + Allopurinol......Page 331
Penicillins + Food......Page 332
Penicillins + Miscellaneous......Page 333
Penicillins + Probenecid......Page 334
Penicillins; Dicloxacillin + Rifampicin......Page 335
Pyrazinamide + Antigout drugs......Page 336
Quinolones + Antacids or Calcium compounds......Page 337
Quinolones + Dairy products......Page 341
Quinolones + Enteral feeds or Food......Page 343
Quinolones + H2-receptor antagonists......Page 344
Quinolones + Iron or Zinc compounds......Page 345
Quinolones + NSAIDs......Page 346
Quinolones + Opioids......Page 347
Quinolones + Other antibacterials......Page 348
Quinolones + Probenecid......Page 349
Quinolones + Sucralfate......Page 350
Quinolones; Lomefloxacin + Furosemide......Page 351
Rifampicin (Rifampin) + Antacids......Page 352
Rifampicin (Rifampin) + Probenecid......Page 353
Tetracyclines + Antacids......Page 354
Tetracyclines + Antiepileptics......Page 355
Tetracyclines + Food or Drinks......Page 356
Tetracyclines + Iron compounds......Page 357
Tetracyclines + Zinc compounds......Page 358
Tetracyclines; Minocycline + Phenothiazines......Page 359
Vancomycin + Theophylline......Page 360
11: Anticholinesterases......Page 361
Anticholinesterases; Centrally acting + Diazepam......Page 362
Anticholinesterases + Miscellaneous......Page 363
Anticholinesterases + Other drugs that affect acetylcholine......Page 364
Anticholinesterases; Centrally acting + SSRIs......Page 365
Tacrine + Quinolones......Page 366
12: Anticoagulants......Page 367
Coumarins + Alcohol......Page 370
Coumarins + Alpha blockers......Page 371
Coumarins and related drugs + Amiodarone......Page 372
Coumarins + Angiotensin II receptor antagonists......Page 373
Coumarins + Antibacterials......Page 374
Coumarins + Antibacterials; Aminosalicylic acid and/or Isoniazid......Page 375
Coumarins + Antibacterials; Cephalosporins and related beta lactams......Page 376
Coumarins + Antibacterials; Clindamycin......Page 377
Coumarins + Antibacterials; Macrolides......Page 378
Coumarins + Antibacterials; Metronidazole or Nimorazole......Page 380
Coumarins + Antibacterials; Penicillins......Page 381
Coumarins + Antibacterials; Quinolones......Page 382
Coumarins + Antibacterials; Rifamycins......Page 384
Coumarins and related drugs + Antibacterials; Sulfonamides and/or Trimethoprim......Page 385
Coumarins and related drugs + Antibacterials; Tetracyclines......Page 386
Coumarins + Antidiabetics; Alpha-glucosidase inhibitors......Page 387
Coumarins + Antidiabetics; Pioglitazone or Rosiglitazone......Page 388
Coumarins and related drugs + Antidiabetics; Sulfonylureas......Page 389
Coumarins + Antineoplastics; Fluorouracil and related prodrugs......Page 390
Coumarins + Antineoplastics; Miscellaneous......Page 391
Coumarins and related drugs + Antiplatelet drugs; Dipyridamole......Page 392
Coumarins + Antiplatelet drugs; Ticlopidine......Page 393
Coumarins and related drugs + Aspirin......Page 394
Coumarins + Azoles; Fluconazole......Page 396
Coumarins and related drugs + Azoles; Miconazole......Page 397
Coumarins + Barbiturates......Page 399
Coumarins + Benzodiazepines and related drugs......Page 400
Coumarins and related drugs + Beta blockers......Page 401
Coumarins + Bile-acid binding resins......Page 402
Coumarins + Broxuridine......Page 403
Coumarins + Carbamazepine or Oxcarbazepine......Page 404
Coumarins + Cloral and derivatives......Page 405
Coumarins and related drugs + Corticosteroids or Corticotropin......Page 406
Coumarins + Danazol or Gestrinone......Page 407
Anticoagulants + Dietary supplements; Ascorbic acid (Vitamin C)......Page 408
Coumarins + Dietary supplements; Levocarnitine......Page 409
Coumarins + Dietary supplements; Vitamin K1–containing......Page 410
Coumarins + Disulfiram......Page 411
Coumarins + Diuretics......Page 412
Coumarins + Felbamate......Page 413
Coumarins and related drugs + Fibrates......Page 414
Coumarins and related drugs + Foods; Enteral and parenteral nutrition......Page 415
Coumarins + Foods; Soya bean products......Page 417
Coumarins and related drugs + Foods; Vitamin K1-rich......Page 418
Coumarins + Glucagon......Page 419
Coumarins + Griseofulvin......Page 420
Coumarins and related drugs + H2-receptor antagonists......Page 421
Coumarins and related drugs + Heparinoids......Page 422
Coumarins + Herbal medicines; Chamomile......Page 423
Coumarins + Herbal medicines; Garlic......Page 424
Coumarins + Herbal medicines; Ginseng......Page 425
Coumarins + Herbal medicines; Quilinggao......Page 426
Coumarins + Herbal medicines; Vitamin K1–rich......Page 427
Coumarins and related drugs + HRT or Tibolone......Page 428
Coumarins + Insecticides......Page 430
Coumarins + Lanthanum......Page 431
Coumarins + Leukotriene antagonists......Page 432
Coumarins + Menthol lozenges......Page 433
Coumarins + Methylphenidate......Page 434
Coumarins + Nefazodone or Trazodone......Page 435
Coumarins and related drugs + NSAIDs......Page 436
Coumarins and related drugs + NSAIDs; Coxibs......Page 437
Coumarins + NSAIDs; Diflunisal......Page 438
Coumarins + NSAIDs; Ibuprofen and related drugs......Page 439
Coumarins + NSAIDs; Metamizole sodium (Dipyrone)......Page 441
Coumarins + NSAIDs; Oxicam derivatives......Page 442
Coumarins and related drugs + NSAIDs; Phenylbutazone and related drugs......Page 443
Coumarins + NSAIDs; Sulindac......Page 444
Coumarins + Opioids; Dextropropoxyphene (Propoxyphene)......Page 445
Coumarins and related drugs + Orlistat......Page 446
Coumarins + Paracetamol (Acetaminophen)......Page 447
Coumarins + Pentoxifylline......Page 449
Coumarins + Pirmenol......Page 450
Coumarins and related drugs + Prostaglandins......Page 451
Coumarins + Protease inhibitors......Page 452
Coumarins + Proton pump inhibitors......Page 453
Coumarins + Quinidine......Page 454
Coumarins + Retinoids......Page 455
Coumarins + Sodium edetate......Page 456
Coumarins and related drugs + SSRIs......Page 457
Coumarins and related drugs + Statins......Page 459
Coumarins + Sucrose polyesters......Page 461
Coumarins + Sulfinpyrazone......Page 462
Coumarins + Terbinafine......Page 463
Coumarins and related drugs + Thyroid and Antithyroid compounds......Page 464
Coumarins + Tobacco......Page 465
Coumarins + Tricyclic antidepressants......Page 466
Coumarins and related drugs + Vitamin K substances......Page 467
Fondaparinux + Antiplatelet drugs and NSAIDs......Page 468
Heparin and LMWHs + Aspirin......Page 469
Heparin + Miscellaneous......Page 470
Heparin + Nitrates......Page 471
Heparin and LMWHs + SSRIs......Page 472
Indanediones + Haloperidol......Page 473
Thrombin inhibitors + Other anticoagulants......Page 474
Thrombin inhibitors; Ximelagatran + Miscellaneous......Page 475
13: Antidiabetics......Page 477
Alpha-glucosidase inhibitors + Other antidiabetics......Page 479
Antidiabetics + Alcohol......Page 480
Antidiabetics + Anabolic steroids......Page 484
Antidiabetics + Antacids......Page 485
Antidiabetics + Antimalarials......Page 486
Antidiabetics + Antipsychotics......Page 487
Antidiabetics + Azoles; Itraconazole or Ketoconazole......Page 488
Antidiabetics + Azoles; Miscellaneous......Page 489
Antidiabetics + Beta blockers......Page 490
Antidiabetics + Calcium-channel blockers......Page 492
Antidiabetics + Cibenzoline (Cifenline)......Page 493
Antidiabetics + Corticosteroids......Page 494
Antidiabetics + Disopyramide......Page 495
Antidiabetics + Diuretics; Thiazide and related......Page 496
Antidiabetics + Fenfluramine......Page 497
Antidiabetics + Fibrates......Page 498
Antidiabetics + Guanethidine and related drugs......Page 499
Antidiabetics + H2-receptor antagonists......Page 500
Antidiabetics + Hormonal contraceptives or HRT......Page 501
Antidiabetics + Isoniazid......Page 502
Antidiabetics + Lithium......Page 503
Antidiabetics + MAOIs or RIMAs......Page 504
Antidiabetics + NSAIDs......Page 505
Antidiabetics + Orlistat......Page 507
Antidiabetics + Quinolones......Page 508
Antidiabetics + Rifamycins......Page 510
Antidiabetics + Somatostatin analogues......Page 511
Antidiabetics + SSRIs......Page 512
Antidiabetics + St John’s wort (Hypericum
perforatum)......Page 513
Antidiabetics + Statins......Page 514
Antidiabetics + Sulfonamides......Page 515
Antidiabetics + Tetracyclines......Page 516
Antidiabetics + Tobacco or Nicotine......Page 518
Antidiabetics + Trimethoprim......Page 519
Metformin + Iodinated contrast media......Page 520
Pioglitazone or Rosiglitazone + Insulin......Page 521
Sitagliptin + Miscellaneous......Page 522
Sulphonylureas; Chlorpropamide + Urinary acidifiers or alkalinisers......Page 523
Sulphonylureas; Tolbutamide + Aprepitant......Page 524
Sulphonylureas; Tolbutamide + Tolcapone......Page 525
14: Antiepileptics......Page 526
Antiepileptics + Antineoplastics; Cytotoxic......Page 527
Antiepileptics + Calcium carbimide or Disulfiram......Page 529
Antiepileptics + Mefloquine......Page 530
Antiepileptics + Quinolones......Page 531
Carbamazepine + Allopurinol......Page 532
Carbamazepine + Antipsychotics......Page 533
Carbamazepine or Oxcarbazepine + Calcium-channel blockers......Page 534
Carbamazepine + Danazol......Page 535
Carbamazepine or Oxcarbazepine + Dextropropoxyphene (Propoxyphene)......Page 536
Carbamazepine + Grapefruit and other fruit juices......Page 537
Carbamazepine + Isoniazid or Rifampicin (Rifampin)......Page 538
Carbamazepine + Lamotrigine......Page 539
Carbamazepine + Macrolides......Page 540
Carbamazepine + Phenobarbital......Page 542
Carbamazepine + Proton pump inhibitors......Page 543
Carbamazepine + SSRIs......Page 544
Carbamazepine + Valnoctamide......Page 545
Carbamazepine + Valproate......Page 546
Carbamazepine + Viloxazine......Page 547
Felbamate + Antacids......Page 548
Gabapentin + Other antiepileptics......Page 549
Lamotrigine + Phenobarbital or Primidone......Page 550
Lamotrigine + Valproate......Page 551
Levetiracetam + Other antiepileptics......Page 552
Mesuximide + Other antiepileptics......Page 553
Oxcarbazepine + Other antiepileptics......Page 554
Phenobarbital + Azoles......Page 555
Phenobarbital + Valproate......Page 556
Phenytoin + Amiodarone......Page 557
Phenytoin + Antidiabetics......Page 558
Phenytoin + Antimycobacterials......Page 559
Phenytoin + Aspirin or NSAIDs......Page 560
Phenytoin + Azoles......Page 561
Phenytoin + Calcium-channel blockers......Page 562
Phenytoin + Carbamazepine......Page 563
Phenytoin + Coumarins and related drugs......Page 564
Phenytoin + Felbamate......Page 566
Phenytoin + Food......Page 567
Phenytoin + H2-receptor antagonists......Page 568
Phenytoin + Macrolides......Page 569
Phenytoin + Nitrofurantoin......Page 570
Phenytoin + Phenobarbital......Page 571
Phenytoin + Proton pump inhibitors......Page 572
Phenytoin + SSRIs......Page 573
Phenytoin + Sulfinpyrazone......Page 574
Phenytoin + Sultiame......Page 575
Phenytoin + Trazodone......Page 576
Phenytoin + Valproate......Page 577
Phenytoin + Zidovudine......Page 578
Primidone + Phenytoin......Page 579
Progabide + Other antiepileptics......Page 580
Retigabine + Other antiepileptics......Page 581
Tiagabine + Other antiepileptics......Page 582
Topiramate + Phenytoin......Page 583
Valproate + Aspirin or NSAIDs......Page 584
Valproate + Carbapenems......Page 585
Valproate + Felbamate......Page 586
Valproate + Methylphenidate......Page 587
Zonisamide + Miscellaneous......Page 588
Zonisamide + Other antiepileptics......Page 589
15: Antihistamines......Page 591
Antihistamines + Azoles......Page 593
Antihistamines + Drugs that prolong the QT interval......Page 596
Antihistamines + Grapefruit and other fruit juices......Page 597
Antihistamines + Macrolides......Page 598
Antihistamines + Nefazodone......Page 601
Antihistamines + SSRIs......Page 602
Antihistamines + Terbinafine......Page 603
Fexofenadine + Rifampicin (Rifampin)......Page 604
Terfenadine + Zileuton......Page 605
16: Antimigraine drugs......Page 606
Ergot derivatives + Heparin......Page 607
Ergot derivatives + Macrolides......Page 608
Ergot derivatives + Protease inhibitors......Page 609
Triptans + Azoles......Page 610
Triptans + Ergot derivatives......Page 611
Triptans + Flunarizine......Page 612
Triptans + MAOIs......Page 613
Triptans + SSRIs and related antidepressants......Page 614
Triptans + Tobacco......Page 615
Triptans; Sumatriptan + Topiramate......Page 616
Triptans; Zolmitriptan + Xylometazoline......Page 617
17: Antineoplastics......Page 618
5-Aminolevulinic acid + St John’s wort (Hypericum perforatum)......Page 619
Anthracyclines + Ciclosporin......Page 620
Anthracyclines + Taxanes......Page 621
Anthracyclines; Epirubicin + Cimetidine......Page 622
Antineoplastics + 5-HT3-receptor antagonists......Page 623
Antineoplastics + Protease inhibitors......Page 624
Antineoplastics + Vaccines......Page 625
Bleomycin + Cisplatin......Page 626
Busulfan + Azoles......Page 627
Cetuximab + Irinotecan......Page 628
Cisplatin + Aminoglycosides......Page 629
Cisplatin + Probenecid......Page 630
Cyclophosphamide or Ifosfamide + Azoles......Page 631
Cyclophosphamide or Ifosfamide + Barbiturates......Page 632
Cyclophosphamide or Ifosfamide + Cisplatin......Page 633
Cyclophosphamide or Ifosfamide + Corticosteroids......Page 634
Cyclophosphamide + Pentostatin......Page 635
Cyclophosphamide + Sulfonamides......Page 636
Erlotinib + Miscellaneous......Page 637
Etoposide + Atovaquone......Page 638
Etoposide + Cisplatin or Carboplatin......Page 639
Fludarabine + Pentostatin......Page 640
Fluorouracil + Dipyridamole......Page 641
Fluorouracil + Interferon alfa......Page 642
Fluorouracil prodrugs; Capecitabine + Allopurinol......Page 643
Gemcitabine + Anthracyclines......Page 644
Gemcitabine + Taxanes......Page 645
Imatinib + Miscellaneous......Page 646
Irinotecan + Antiepileptics......Page 647
Irinotecan + Milk thistle......Page 648
Irinotecan + St John’s wort (Hypericum
perforatum)......Page 649
Melphalan + Food......Page 650
Methotrexate + Antibacterials; Cefotiam......Page 651
Methotrexate + Antibacterials; Penicillins......Page 652
Methotrexate + Antibacterials; Vancomycin......Page 654
Methotrexate + Caffeine......Page 655
Methotrexate + Corticosteroids......Page 656
Methotrexate + Food......Page 657
Methotrexate + NSAIDs......Page 658
Methotrexate + Proton pump inhibitors......Page 661
Methotrexate + Sulfasalazine......Page 662
Mitomycin + Doxorubicin......Page 663
Nitrosoureas + Cimetidine......Page 664
Procarbazine + Chlormethine (Mechlorethamine)......Page 665
Sorafenib + Miscellaneous......Page 666
Tamoxifen and other anti-oestrogens + Herbal medicines......Page 667
Tamoxifen + SSRIs......Page 668
Taxanes + Cisplatin or Carboplatin......Page 669
Taxanes + Protease inhibitors......Page 670
Taxanes; Paclitaxel + Ketoconazole......Page 671
Thalidomide + Doxorubicin......Page 672
Thiopurines + Allopurinol......Page 673
Thiopurines + 5-Aminosalicylates......Page 674
Thiopurines; Mercaptopurine + Food......Page 675
Toremifene + Antiepileptics......Page 676
Vinca alkaloids + Azoles......Page 677
Vinca alkaloids + Mitomycin......Page 678
Vinca alkaloids; Vincristine + Asparaginase......Page 679
Vinca alkaloids; Vincristine + Nifedipine......Page 680
18: Antiparkinsonian and related drugs......Page 681
Amantadine + Quinidine or Quinine......Page 682
Antimuscarinics + Areca (Betel nuts)......Page 683
Apomorphine + Antihypertensives......Page 684
Apomorphine + Miscellaneous......Page 685
Bromocriptine and other dopamine agonists + Food......Page 686
Bromocriptine + Proton pump inhibitors......Page 687
COMT inhibitors + MAOIs......Page 688
COMT inhibitors + Tricyclic and related antidepressants......Page 689
Levodopa + Anticholinesterases; Centrally acting......Page 690
Levodopa + Antimuscarinics......Page 691
Levodopa + Benzodiazepines and related drugs......Page 692
Levodopa + Bromocriptine and other dopamine agonists......Page 693
Levodopa + COMT inhibitors......Page 694
Levodopa + Indinavir......Page 695
Levodopa + MAO-B inhibitors......Page 696
Levodopa + Papaverine......Page 697
Levodopa + Pyridoxine (Vitamin B6)......Page 698
Levodopa + Tricyclic antidepressants......Page 699
MAO-B inhibitors + Antidepressants......Page 700
MAO-B inhibitors + MAOIs or RIMAs......Page 701
MAO-B inhibitors + Tyramine-rich foods......Page 702
MAO-B inhibitors; Selegiline + Hormonal contraceptives or HRT......Page 703
Pramipexole + Drugs altering its renal clearance......Page 704
Ropinirole + Miscellaneous......Page 705
19: Thrombolytics......Page 706
Antiplatelet drugs + Aspirin......Page 707
Antiplatelet drugs + Herbal medicines......Page 708
Cilostazol + Miscellaneous......Page 709
Clopidogrel + Miscellaneous......Page 710
Dipyridamole + Beta blockers......Page 711
Glycoprotein IIb/IIIa antagonists + Drugs that affect coagulation......Page 712
Streptokinase + Other thrombolytics......Page 713
Ticlopidine + Miscellaneous......Page 714
20: Antipsychotics, Anxiolytics and Hypnotics......Page 715
Antipsychotics + Antiepileptics......Page 716
Antipsychotics + Antimuscarinics......Page 717
Antipsychotics + Lithium......Page 719
Antipsychotics + SSRIs......Page 721
Aripiprazole + Lithium......Page 723
Aripiprazole + Valproate......Page 724
Benzodiazepines + Antacids......Page 725
Benzodiazepines and related drugs + Antiepileptics; Carbamazepine......Page 726
Benzodiazepines + Antiepileptics; Phenytoin......Page 727
Benzodiazepines + Antiepileptics; Valproate......Page 728
Benzodiazepines + Antipsychotics......Page 729
Benzodiazepines and related drugs + Azoles......Page 730
Benzodiazepines and related drugs + Beta blockers......Page 732
Benzodiazepines + Calcium-channel blockers......Page 733
Benzodiazepines + Disulfiram......Page 734
Benzodiazepines + Grapefruit juice......Page 735
Benzodiazepines and related drugs + H2-receptor antagonists......Page 736
Benzodiazepines and related drugs + Hormonal contraceptives......Page 737
Benzodiazepines + Isoniazid......Page 738
Benzodiazepines and related drugs + Macrolides......Page 739
Benzodiazepines + Modafinil......Page 741
Benzodiazepines and related drugs + NSAIDs......Page 742
Benzodiazepines and related drugs + Protease inhibitors......Page 743
Benzodiazepines + Quinolones......Page 744
Benzodiazepines + Saw palmetto......Page 745
Benzodiazepines and related drugs + SSRIs......Page 746
Benzodiazepines + Tadalafil......Page 748
Benzodiazepines and related drugs + Xanthines......Page 749
Buspirone + Herbal medicines......Page 750
Buspirone + Protease inhibitors......Page 751
Chlorpromazine + Tetrabenazine......Page 752
Clozapine + Antiepileptics......Page 753
Clozapine + Azoles......Page 754
Clozapine + Drugs that suppress bone marrow......Page 755
Clozapine + Hormonal contraceptives......Page 756
Clozapine + Miscellaneous......Page 757
Clozapine + Quinolones......Page 758
Clozapine + SSRIs......Page 759
Glutethimide + Tobacco......Page 761
Haloperidol + Granisetron......Page 762
Haloperidol + Nefazodone......Page 763
Olanzapine + Antiepileptics......Page 764
Olanzapine + Miscellaneous......Page 765
Olanzapine + SSRIs......Page 766
Olanzapine + Tricyclic and related antidepressants......Page 767
Phenothiazines + Barbiturates......Page 768
Phenothiazines + Tricyclic antidepressants......Page 769
Pimozide + CYP3A4 inhibitors......Page 770
Quetiapine + Antipsychotics......Page 771
Quetiapine + Miscellaneous......Page 772
Risperidone + Carbamazepine or Oxcarbazepine......Page 773
Risperidone + Probenecid......Page 774
Risperidone + SSRIs......Page 775
Risperidone + Valproate......Page 776
Sertindole + Miscellaneous......Page 777
Ziprasidone + Carbamazepine......Page 778
Zotepine + Miscellaneous......Page 779
21: Antivirals......Page 781
Aciclovir and related drugs + Mycophenolate......Page 783
Adefovir + Miscellaneous......Page 784
Enfuvirtide + Cytochrome P450 isoenzyme substrates......Page 785
Foscarnet + Ciprofloxacin......Page 786
Ganciclovir + Trimethoprim......Page 787
Interferons + Analgesics or Corticosteroids......Page 788
Maraviroc + CYP3A4 inhibitors......Page 789
Maraviroc + Miscellaneous......Page 790
NNRTIs + Azoles; Itraconazole......Page 791
NNRTIs + Azoles; Voriconazole......Page 792
NNRTIs + Macrolides......Page 793
NNRTIs + Protease inhibitors......Page 794
NNRTIs + Rifamycins......Page 799
NRTIs + Aciclovir and related drugs......Page 800
NRTIs + Antimycobacterials......Page 801
NRTIs + Atovaquone......Page 802
NRTIs + Azoles......Page 803
NRTIs + Cytokines......Page 804
NRTIs + Dapsone......Page 805
NRTIs + Food......Page 806
NRTIs + Ganciclovir......Page 807
NRTIs + Hydroxycarbamide......Page 808
NRTIs + NRTIs......Page 809
NRTIs + Paracetamol (Acetaminophen)......Page 811
NRTIs + Probenecid......Page 812
NRTIs + Protease inhibitors......Page 813
NRTIs + Ribavirin......Page 814
NRTIs + Tenofovir......Page 815
NRTIs; Zidovudine + Drugs that inhibit glucuronidation......Page 817
Oseltamivir + Drugs that affect renal clearance......Page 818
Protease inhibitors + Antiepileptics; Carbamazepine......Page 819
Protease inhibitors + Antiepileptics; Lamotrigine......Page 820
Protease inhibitors + Antiepileptics; Valproate......Page 821
Protease inhibitors + Azoles; Fluconazole......Page 822
Protease inhibitors + Azoles; Ketoconazole......Page 823
Protease inhibitors + Azoles; Voriconazole......Page 824
Protease inhibitors + Drugs that affect gastric pH......Page 825
Protease inhibitors + Food......Page 827
Protease inhibitors + Macrolides......Page 828
Protease inhibitors + Miscellaneous......Page 830
Protease inhibitors + Protease inhibitors......Page 831
Protease inhibitors + Rifamycins......Page 834
Protease inhibitors + St John’s wort (Hypericum
perforatum)......Page 837
Protease inhibitors + Tenofovir......Page 838
Protease inhibitors; Indinavir + Milk thistle......Page 839
Telbivudine + Miscellaneous......Page 840
Vidarabine + Allopurinol......Page 841
22: Beta blockers......Page 842
Beta blockers + Anticholinesterases......Page 843
Beta blockers + Aspirin or NSAIDs......Page 844
Beta blockers + Barbiturates......Page 846
Beta blockers + Calcium-channel blockers; Dihydropyridines......Page 847
Beta blockers + Calcium-channel blockers; Diltiazem......Page 849
Beta blockers + Calcium-channel blockers; Verapamil......Page 850
Beta blockers + Diphenhydramine......Page 851
Beta blockers + Fish oils......Page 852
Beta blockers + Grapefruit and other fruit juices......Page 853
Beta blockers + H2-receptor antagonists; Cimetidine......Page 854
Beta blockers + H2-receptor antagonists; Ranitidine......Page 855
Beta blockers + Hydralazine......Page 856
Beta blockers + Inotropes and Vasopressors......Page 857
Beta blockers + Itraconazole......Page 858
Beta blockers + Penicillins......Page 859
Beta blockers + Phenylpropanolamine......Page 860
Beta blockers + Propafenone......Page 861
Beta blockers + Quinidine......Page 862
Beta blockers + Rifampicin (Rifampin)......Page 863
Beta blockers + SSRIs......Page 864
Beta blockers + Tobacco ± Coffee and Tea......Page 865
Metoprolol + Acetylcholine......Page 866
Propranolol + Sucrose polyesters......Page 867
Talinolol + Sulfasalazine......Page 868
23: Calcium-channel blockers......Page 869
Calcium-channel blockers + Aspirin or NSAIDs......Page 870
Calcium-channel blockers + Bile-acid binding resins......Page 873
Calcium-channel blockers + Calcium compounds......Page 874
Calcium-channel blockers + Dantrolene......Page 875
Calcium-channel blockers + Fluoxetine......Page 876
Calcium-channel blockers + Food......Page 877
Calcium-channel blockers + Grapefruit juice......Page 878
Calcium-channel blockers + H2-receptor antagonists......Page 879
Calcium-channel blockers + Macrolides......Page 880
Calcium-channel blockers + Magnesium compounds......Page 881
Calcium-channel blockers + Phenobarbital......Page 882
Calcium-channel blockers + Proton pump inhibitors......Page 883
Calcium-channel blockers + Rifampicin (Rifampin)......Page 884
Calcium-channel blockers + Vancomycin......Page 885
Calcium-channel blockers + Zidovudine......Page 886
24: Cardiovascular drugs, miscellaneous......Page 887
Antihypertensives + Phenylpropanolamine......Page 889
Clonidine + Beta blockers......Page 891
Clonidine + Hormonal contraceptives......Page 892
Clonidine + Tricyclic and related antidepressants......Page 893
Glyceryl trinitrate (Nitroglycerin) + Antimuscarinics......Page 894
Guanethidine + Amfetamines and related drugs......Page 895
Guanethidine + MAOIs......Page 896
Guanfacine + Phenobarbital or Phenytoin......Page 897
Inotropes and Vasopressors + Antimuscarinics......Page 898
Inotropes and Vasopressors + Cimetidine......Page 899
Inotropes and Vasopressors + Guanethidine......Page 900
Inotropes and Vasopressors + Reserpine......Page 901
Inotropes and Vasopressors; Dopamine + Tolazoline......Page 902
Ketanserin + Beta blockers......Page 903
Levosimendan + Miscellaneous......Page 904
Methyldopa + Haloperidol......Page 905
Methyldopa + Phenoxybenzamine......Page 906
Minoxidil + Miscellaneous......Page 907
Nicorandil + Miscellaneous......Page 908
Ranolazine + Miscellaneous......Page 909
Tirilazad mesilate + Miscellaneous......Page 910
Tolazoline + H2-receptor antagonists......Page 911
25: Digitalis glycosides......Page 912
Digitalis glycosides + Acipimox......Page 913
Digitalis glycosides + Alpha-glucosidase inhibitors......Page 914
Digitalis glycosides + Aminosalicylic acid......Page 915
Digitalis glycosides + Amiodarone......Page 916
Digitalis glycosides + Antacids......Page 917
Digitalis glycosides + Antiepileptics; Phenytoin......Page 918
Digitalis glycosides + Azoles; Itraconazole......Page 919
Digitalis glycosides + Benzodiazepines and related drugs......Page 920
Digitalis glycosides + Beta blockers......Page 921
Digitalis glycosides + Beta-lactam antibacterials......Page 922
Digitalis glycosides + Calcium-channel blockers......Page 923
Digitalis glycosides + Calcium-channel blockers; Nifedipine......Page 924
Digitalis glycosides + Calcium-channel blockers; Verapamil......Page 925
Digitalis glycosides + Chloroquine or Hydroxychloroquine......Page 926
Digitalis glycosides + Colestipol......Page 927
Digitalis glycosides + Darifenacin or Solifenacin......Page 928
Digitalis glycosides + Dihydroergocryptine......Page 929
Digitalis glycosides + Diuretics; Potassium-depleting......Page 930
Digitalis glycosides + Dofetilide......Page 931
Digitalis glycosides + Edrophonium......Page 932
Digitalis glycosides + Flecainide......Page 933
Digitalis glycosides + Herbal medicines; Cimicifuga......Page 934
Digitalis glycosides + Herbal medicines; Goldenseal (Hydrastis)......Page 935
Digitalis glycosides + Herbal medicines; St John’s wort (Hypericum perforatum)......Page 936
Digitalis glycosides + Lithium......Page 937
Digitalis glycosides + Macrolides......Page 938
Digitalis glycosides + Methyldopa......Page 939
Digitalis glycosides + Moracizine......Page 940
Digitalis glycosides + NSAIDs......Page 941
Digitalis glycosides + Probenecid......Page 943
Digitalis glycosides + Prostaglandins......Page 944
Digitalis glycosides + Quinidine......Page 945
Digitalis glycosides + Quinolones......Page 946
Digitalis glycosides + Rifamycins......Page 947
Digitalis glycosides + SSRIs......Page 948
Digitalis glycosides + Sucralfate......Page 949
Digitalis glycosides + Thyroid hormones and Antithyroid drugs......Page 950
Digitalis glycosides + Valaciclovir......Page 951
Digitalis glycosides + Zileuton......Page 952
26: Diuretics......Page 953
Eplerenone + CYP3A4 inhibitors......Page 954
Furosemide + Bile-acid binding resins......Page 955
Furosemide + Sevelamer......Page 956
Loop diuretics + H2-receptor antagonists......Page 957
Loop diuretics + NSAIDs......Page 958
Loop diuretics + Probenecid......Page 960
Potassium-sparing diuretics + NSAIDs......Page 961
Potassium-sparing/Thiazide diuretics + Trimethoprim......Page 962
Spironolactone + Colestyramine......Page 963
Thiazide diuretics + Calcium and/or Vitamin D......Page 964
Thiazide and related diuretics + NSAIDs......Page 965
Thiazide diuretics + Propantheline......Page 968
27: Gastrointestinal drugs......Page 969
Bismuth compounds + Proton pump inhibitors......Page 970
Carbenoxolone + Sulphonylureas......Page 971
Enteral feeds + Aluminium compounds and/or Sucralfate......Page 972
H2-receptor antagonists + Antacids......Page 975
Loperamide + Colestyramine......Page 976
Mesalazine (Mesalamine) + Proton pump inhibitors......Page 977
Proton pump inhibitors + Antacids......Page 978
Proton pump inhibitors + Food or Drinks......Page 979
Proton pump inhibitors + Macrolides......Page 980
Proton pump inhibitors + Penicillins......Page 981
Sulfasalazine + Antibacterials......Page 982
Sulfasalazine + Zileuton......Page 983
28: Hormonal contraceptives and Sex hormones......Page 984
Emergency hormonal contraceptives + Enzyme inducers......Page 986
Hormonal contraceptives + Antibacterials; Cephalosporins......Page 987
Hormonal contraceptives + Antibacterials; Macrolides......Page 988
Hormonal contraceptives + Antibacterials; Miscellaneous......Page 989
Hormonal contraceptives + Antibacterials; Penicillins......Page 990
Hormonal contraceptives + Antibacterials; Sulfonamides and/or Trimethoprim......Page 991
Hormonal contraceptives + Antibacterials; Tetracyclines......Page 992
Hormonal contraceptives or HRT + Antibacterials; Troleandomycin......Page 993
Hormonal contraceptives + Antiepileptics; Barbiturates or Phenytoin......Page 994
Hormonal contraceptives + Antiepileptics; Ethosuximide......Page 996
Hormonal contraceptives + Antiepileptics; Lamotrigine......Page 997
Hormonal contraceptives + Antiepileptics; Retigabine......Page 998
Hormonal contraceptives + Antiepileptics; Valproate......Page 999
Hormonal contraceptives + Antimalarials......Page 1000
Hormonal contraceptives or HRT + Ascorbic acid (Vitamin C)......Page 1001
Hormonal contraceptives or HRT + Azoles......Page 1002
Hormonal contraceptives or HRT + Coxibs......Page 1003
Hormonal contraceptives + Griseofulvin......Page 1004
Hormonal contraceptives + Moclobemide......Page 1005
Hormonal contraceptives + NNRTIs......Page 1006
Hormonal contraceptives or HRT + Protease inhibitors......Page 1007
Hormonal contraceptives or HRT + Proton pump inhibitors......Page 1008
Hormonal contraceptives + Retinoids......Page 1009
Hormonal contraceptives + Rifamycins......Page 1010
Hormonal contraceptives + St John’s wort (Hypericum perforatum)......Page 1011
Hormonal contraceptives + Tobacco......Page 1012
Hormonal contraceptives or HRT + Triptans......Page 1013
HRT + Moexipril......Page 1014
Oestrogens + Grapefruit juice......Page 1015
Progestogen-only contraceptives + Enzyme inducers......Page 1016
Tibolone + Enzyme inducers......Page 1017
29: Immunosuppressants......Page 1018
Ciclosporin + ACE inhibitors and Angiotensin II receptor antagonists......Page 1019
Ciclosporin + Aciclovir and related drugs......Page 1020
Ciclosporin + Amiodarone......Page 1021
Ciclosporin + Amphotericin B......Page 1022
Ciclosporin + Antibacterials; Cephalosporins......Page 1023
Ciclosporin + Antibacterials; Imipenem/Cilastatin......Page 1024
Ciclosporin + Antibacterials; Macrolides......Page 1025
Ciclosporin + Antibacterials; Metronidazole......Page 1026
Ciclosporin + Antibacterials; Quinolones......Page 1027
Ciclosporin + Antibacterials; Sulfonamides and/or Trimethoprim......Page 1028
Ciclosporin + Antidiabetics......Page 1029
Ciclosporin + Antiepileptics......Page 1030
Ciclosporin + Antimycobacterials......Page 1031
Ciclosporin + Azoles......Page 1032
Ciclosporin + Bile acids or Ursodeoxycholic acid (Ursodiol)......Page 1034
Ciclosporin + Busulfan and Cyclophosphamide......Page 1035
Ciclosporin + Calcium-channel blockers......Page 1036
Ciclosporin + Clonidine......Page 1038
Ciclosporin + Corticosteroids......Page 1039
Ciclosporin + Coumarins......Page 1040
Ciclosporin + Diuretics......Page 1041
Ciclosporin + Food or Drinks......Page 1042
Ciclosporin + Grapefruit and other fruit juices......Page 1043
Ciclosporin + H2-receptor antagonists......Page 1044
Ciclosporin + Herbal medicines; Geum chiloense......Page 1045
Ciclosporin + Herbal medicines; St John’s wort (Hypericum perforatum)......Page 1046
Ciclosporin + Methotrexate......Page 1047
Ciclosporin + Modafinil......Page 1048
Ciclosporin + NSAIDs, Aspirin or Paracetamol (Acetaminophen)......Page 1049
Ciclosporin + Opioids......Page 1050
Ciclosporin + Probucol......Page 1051
Ciclosporin + Protease inhibitors......Page 1052
Ciclosporin + Quinine......Page 1053
Ciclosporin + Sibutramine......Page 1054
Ciclosporin + SSRIs and related antidepressants......Page 1055
Ciclosporin + Terbinafine......Page 1056
Ciclosporin + Vitamins......Page 1057
Corticosteroids + Antithyroid drugs......Page 1058
Corticosteroids + Azoles; Itraconazole......Page 1059
Corticosteroids + Azoles; Ketoconazole......Page 1060
Corticosteroids + Barbiturates......Page 1061
Corticosteroids + Carbamazepine......Page 1062
Corticosteroids + Ephedrine......Page 1063
Corticosteroids + Hormonal contraceptives and Sex hormones......Page 1064
Corticosteroids + Macrolides......Page 1065
Corticosteroids + Nefazodone......Page 1066
Corticosteroids + Omeprazole......Page 1067
Corticosteroids + Phenytoin......Page 1068
Corticosteroids + Protease inhibitors......Page 1069
Corticosteroids + Vaccines; Live......Page 1070
Etanercept + Miscellaneous......Page 1071
Everolimus + Rifampicin (Rifampin)......Page 1072
Immunosuppressants + Vaccines......Page 1073
Leflunomide + Miscellaneous......Page 1074
Mycophenolate + Allopurinol......Page 1075
Mycophenolate + Ciclosporin or Tacrolimus......Page 1076
Mycophenolate + Metronidazole......Page 1077
Mycophenolate + Sevelamer......Page 1078
Sirolimus + ACE inhibitors......Page 1079
Sirolimus + Azoles......Page 1080
Sirolimus + Ciclosporin......Page 1081
Sirolimus + Macrolides......Page 1082
Sirolimus + Rifamycins......Page 1083
Tacrolimus + Azoles......Page 1084
Tacrolimus + Chloramphenicol......Page 1086
Tacrolimus + Echinocandins......Page 1087
Tacrolimus + Macrolides......Page 1088
Tacrolimus + Miscellaneous......Page 1089
Tacrolimus + Phenytoin......Page 1090
Tacrolimus + Proton pump inhibitors......Page 1091
Tacrolimus + Sevelamer......Page 1092
Tacrolimus + SSRIs and related antidepressants......Page 1093
Tacrolimus + Theophylline......Page 1094
30: Lipid regulating drugs......Page 1095
Ezetimibe + Rifampicin (Rifampin)......Page 1097
Fibrates + Diuretics......Page 1098
Fibrates; Ciprofibrate + Ibuprofen......Page 1099
Statins + ACE inhibitors......Page 1100
Statins + Angiotensin II receptor antagonists......Page 1101
Statins + Azoles......Page 1102
Statins + Beta blockers......Page 1103
Statins + Calcium-channel blockers......Page 1104
Statins + Carbamazepine......Page 1105
Statins + Ciclosporin......Page 1106
Statins + Diuretics......Page 1108
Statins + Fibrates......Page 1109
Statins + Fusidic acid......Page 1111
Statins + Grapefruit and other fruit juices......Page 1112
Statins + Macrolides......Page 1113
Statins + Nefazodone......Page 1114
Statins + NNRTIs......Page 1115
Statins + Phosphodiesterase type-5 inhibitors......Page 1116
Statins + Rifampicin (Rifampin)......Page 1117
Statins; Pravastatin + Mianserin......Page 1118
Statins; Simvastatin + Fish oils......Page 1119
31: Lithium......Page 1120
Lithium + Acetazolamide......Page 1121
Lithium + Antibacterials......Page 1122
Lithium + Antibacterials; Tetracyclines......Page 1123
Lithium + Antidepressants; SSRIs......Page 1124
Lithium + Antidepressants; Venlafaxine......Page 1126
Lithium + Antiepileptics; Lamotrigine......Page 1127
Lithium + Aspirin or other Salicylates......Page 1128
Lithium + Calcitonin (Salcatonin)......Page 1129
Lithium + Cisplatin......Page 1130
Lithium + Diuretics; Potassium-sparing......Page 1131
Lithium + Diuretics; Thiazide and related......Page 1132
Lithium + Iodides......Page 1133
Lithium + NSAIDs......Page 1134
Lithium + Sodium compounds......Page 1137
Lithium + Triptans......Page 1138
32: MAOIs......Page 1139
MAOIs or RIMAs + Antihypertensives......Page 1140
MAOIs or RIMAs + Benzodiazepines......Page 1141
MAOIs + Caffeine or Choline theophyllinate......Page 1142
MAOIs or RIMAs + Dextromethorphan......Page 1143
MAOIs + Doxapram......Page 1144
MAOIs or RIMAs + Lithium......Page 1145
MAOIs + Mazindol......Page 1146
MAOIs + Opioids; Fentanyl and related drugs......Page 1147
MAOIs + Opioids; Miscellaneous......Page 1148
MAOIs or RIMAs + Opioids; Pethidine (Meperidine)......Page 1149
MAOIs or RIMAs + Phenothiazines......Page 1150
MAOIs or RIMAs + SSRIs......Page 1151
MAOIs or RIMAs + Sympathomimetics; Amfetamines and related drugs......Page 1153
MAOIs or RIMAs + Sympathomimetics; Directly-acting......Page 1155
MAOIs or RIMAs + Sympathomimetics; Indirectly-acting......Page 1156
MAOIs or RIMAs + Sympathomimetics; Phenylephrine......Page 1157
MAOIs or RIMAs + Tricyclic and related antidepressants......Page 1158
MAOIs or RIMAs + Tyramine-rich drinks......Page 1160
MAOIs or RIMAs + Tyramine-rich foods......Page 1162
MAOIs or RIMAs + Venlafaxine......Page 1165
RIMAs; Moclobemide + Omeprazole......Page 1166
33: Respiratory drugs......Page 1167
Anti-asthma drugs + Beta blockers......Page 1169
Anti-asthma drugs + NSAIDs......Page 1170
Caffeine + Allopurinol......Page 1171
Caffeine + Class I antiarrhythmics......Page 1172
Caffeine + Fluvoxamine......Page 1173
Caffeine + Menthol......Page 1174
Caffeine + Saw palmetto......Page 1175
Doxofylline + Miscellaneous......Page 1177
Montelukast + Antiepileptics......Page 1178
Theophylline + Allopurinol......Page 1179
Theophylline + Anthelmintics; Benzimidazoles......Page 1180
Theophylline + Antihistamines and related drugs......Page 1181
Theophylline + Barbiturates......Page 1182
Theophylline + Beta-agonist bronchodilators......Page 1183
Theophylline + Caffeine......Page 1184
Theophylline + Calcium-channel blockers......Page 1185
Theophylline + Clopidogrel or Ticlopidine......Page 1186
Theophylline + Dextropropoxyphene (Propoxyphene)......Page 1187
Theophylline + Ephedrine......Page 1188
Theophylline + Furosemide......Page 1189
Theophylline + H2-receptor antagonists......Page 1190
Theophylline + Influenza vaccines......Page 1192
Theophylline + Interferons......Page 1193
Theophylline + Macrolides......Page 1194
Theophylline + Macrolides; Erythromycin......Page 1196
Theophylline + Mexiletine or Tocainide......Page 1197
Theophylline + Penicillins......Page 1198
Theophylline + Pirenzepine......Page 1199
Theophylline + Proton pump inhibitors......Page 1200
Theophylline + Quinolones......Page 1201
Theophylline + Rifamycins and/or Isoniazid......Page 1205
Theophylline + SSRIs......Page 1206
Theophylline + Sucralfate......Page 1207
Theophylline + Terbinafine......Page 1208
Theophylline + Thyroid and Antithyroid compounds......Page 1209
Theophylline + Viloxazine......Page 1210
Zafirlukast + Terfenadine......Page 1211
34: SSRIs, Tricyclics and related antidepressants......Page 1212
Bupropion + Carbimazole......Page 1213
Bupropion + Methylphenidate......Page 1214
Maprotiline + Hormonal contraceptives or Tobacco......Page 1215
Mianserin + Antiepileptics......Page 1216
Mirtazapine + Antiepileptics......Page 1217
Nefazodone + Antidepressants......Page 1218
Reboxetine + CYP3A4 inhibitors......Page 1219
SNRIs + St John’s wort (Hypericum perforatum)......Page 1220
SNRIs; Venlafaxine + Antidepressants......Page 1221
SNRIs; Venlafaxine + Antihypertensives......Page 1222
SNRIs; Venlafaxine + Miscellaneous......Page 1223
SSRIs + Bupropion......Page 1224
SSRIs + Cyproheptadine......Page 1225
SSRIs + Grapefruit juice......Page 1226
SSRIs + 5-HT3-receptor antagonists......Page 1227
SSRIs + Macrolides......Page 1228
SSRIs + Opioids......Page 1229
SSRIs + Opioids; Methadone......Page 1230
SSRIs + Opioids; Tramadol......Page 1231
SSRIs + Protease inhibitors......Page 1232
SSRIs + St John’s wort (Hypericum perforatum)......Page 1233
SSRIs + Tryptophan......Page 1234
SSRIs; Fluoxetine + CYP2D6 substrates......Page 1235
Trazodone + Antidepressants......Page 1236
Trazodone + Haloperidol......Page 1237
Tricyclic antidepressants + ACE inhibitors......Page 1238
Tricyclic antidepressants + Azoles; Fluconazole......Page 1239
Tricyclic antidepressants + Benzodiazepines and related drugs......Page 1240
Tricyclic antidepressants + Bupropion......Page 1241
Tricyclic antidepressants + Calcium-channel blockers......Page 1242
Tricyclic antidepressants + Colestyramine......Page 1243
Tricyclic antidepressants + Fenfluramine......Page 1244
Tricyclic antidepressants + H2-receptor antagonists......Page 1245
Tricyclic antidepressants + Inotropes and Vasopressors......Page 1246
Tricyclic antidepressants + Oestrogens......Page 1247
Tricyclic antidepressants + Quinidine or Quinine......Page 1248
Tricyclic antidepressants + SNRIs; Venlafaxine......Page 1249
Tricyclic and related antidepressants + SSRIs......Page 1250
Tricyclic antidepressants + Thyroid hormones......Page 1252
Tricyclic antidepressants + Valproate......Page 1253
Tricyclic antidepressants; Clomipramine + Oxybutynin......Page 1254
Tricyclic antidepressants; Imipramine + Vinpocetine......Page 1255
Allopurinol + Iron compounds......Page 1256
Aluminium hydroxide + Ascorbic acid (Vitamin C) or Citrates......Page 1257
Aprepitant + CYP3A4 inducers......Page 1258
Benzbromarone + Aspirin......Page 1259
Bisphosphonates + Aspirin or NSAIDs......Page 1260
Black cohosh + Cytochrome P450 isoenzyme substrates......Page 1261
CNS depressants + CNS depressants......Page 1262
Contrast media + Phenothiazines......Page 1263
Dextromethorphan + Bupropion......Page 1264
Dextromethorphan + Saw palmetto......Page 1265
Enteric-coated, delayed-release preparations + Drugs that affect gastric pH......Page 1266
Folic acid + Sulfasalazine......Page 1267
5-HT3-receptor antagonists + Aprepitant......Page 1268
5-HT3-receptor antagonists + Enzyme inducers......Page 1269
Iron chelators; Deferasirox + Miscellaneous......Page 1270
Iron compounds or Vitamin B12 + Chloramphenicol......Page 1271
Iron compounds + H2-receptor antagonists......Page 1272
Melatonin + Caffeine......Page 1273
Nicotine + Vasopressin......Page 1274
Penicillamine + Food......Page 1275
Phenylpropanolamine + Indinavir......Page 1276
Phosphodiesterase type-5 inhibitors + Alpha blockers......Page 1277
Phosphodiesterase type-5 inhibitors + Antihypertensives......Page 1278
Phosphodiesterase type-5 inhibitors + Azoles......Page 1279
Phosphodiesterase type-5 inhibitors + H2-receptor antagonists......Page 1280
Phosphodiesterase type-5 inhibitors + Nitrates......Page 1281
Phosphodiesterase type-5 inhibitors + Protease inhibitors......Page 1282
Phosphodiesterase type-5 inhibitors; Sildenafil + Bosentan......Page 1283
Pseudoephedrine + Antacids or Antidiarrhoeals......Page 1284
Pseudoephedrine and related drugs + Caffeine......Page 1285
Raloxifene + Miscellaneous......Page 1286
Ritodrine + Miscellaneous......Page 1287
Sodium polystyrene sulfonate + Antacids......Page 1288
Thyroid hormones + Antacids......Page 1289
Thyroid hormones + Calcium carbonate......Page 1290
Thyroid hormones + HRT......Page 1291
Thyroid hormones + Proton pump inhibitors......Page 1292
Thyroid hormones + Sertraline......Page 1293
Thyroid hormones + Sucralfate......Page 1294
Tizanidine + CYP1A2 inhibitors......Page 1295
Trientine + Miscellaneous......Page 1296
Urinary antimuscarinics; Oxybutynin + CYP3A4 inhibitors......Page 1297
Urinary antimuscarinics; Tolterodine + Duloxetine......Page 1298
Vitamin A (Retinol) + Neomycin......Page 1299
Vitamins + Orlistat......Page 1300
Zinc sulphate + Calcium compounds......Page 1301
Index......Page 1302