Stem Cells: From Basic Research to Therapy, Volume 2: Tissue Homeostasis and Regeneration during Adulthood, Applications, Legislation and Ethics

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The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, and industry. The book closes with an outlook on generalized approaches that can be used to solve legislative and ethical challenges.

Author(s): F Gage; Yves Christen
Series: Research and perspectives in neurosciences, v.20
Publisher: Springer, CRC Press
Year: 2014

Language: English
Pages: 474
City: Berlin ; New York
Tags: Биологические дисциплины;Цитология;Стволовые клетки;


Content: iPS Cell Technology and Disease Research: Issues To Be Resolved / Rudolf Jaenisch --
Therapeutic Somatic Cell Reprogramming by Nuclear Transfer / Stan Wang, John B. Gurdon --
Induction of Neural Lineages from Mesoderm and Endoderm by Defined Transcription Factors / Marius Wernig --
Proposing a Model for Studying Primate Development Using Induced Pluripotent Stem Cells / Maria C. N. Marchetto, Alysson R. Muotri --
HTT Evolution and Brain Development / Chiara Zuccato, Elena Cattaneo --
Human Pluripotent and Multipotent Stem Cells as Tools for Modeling Neurodegeneration / Jerome Mertens, Philipp Koch, Oliver Brüstle --
Human Stem Cell Approaches to Understanding and Treating Alzheimer's Disease / Lawrence S. B. Goldstein --
Potential of Stem Cell-Derived Motor Neurons for Modeling Amyotrophic Lateral Sclerosis (ALS) / Derek H. Oakley, Gist F. Croft --
Using Pluripotent Stem Cells to Decipher Mechanisms and Identify Treatments for Diseases That Affect the Brain / Marc Peschanski, Cécile Martinat --
Modeling Autism Spectrum Disorders Using Human Neurons / Alysson Renato Muotri --
On the Search for Reliable Human Aging Models: Understanding Aging by Nuclear Reprogramming / Ignacio Sancho-Martinez, Emmanuel Nivet.
Abstract:
Written by leading experts in the field, this book examines the latest research on neurodegenerative diseases and presents prospects for novel therapies. Read more...