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Statistical methods in drug combination studies

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Author(s): Wei Zhao; Harry Yang
Series: Chapman & Hall/CRC biostatistics series
Publisher: Chapman & Hall/CRC
Year: 2015

Language: English
Pages: 236
City: Boca Raton
Tags: Медицинские дисциплины;Социальная медицина и медико-биологическая статистика;


Content:
Drug Combination: Much Promise and Many Hurdles. Drug Combination Synergy. Drug Combination Design Strategies. Confidence Interval for Interaction Index. Two-Stage Response Surface Approaches to Modeling Drug Interaction. A Bayesian Industry Approach to Phase I Combination Trials in Oncology. Statistical Methodology for Evaluation Combination Therapy in Clinical Trials. Challenges and Opportunities in Analysis of Drug Combination Clinical Trial Data. Statistical Computational Tools for ADA Analysis.