product iamge

Sinonasal and Skull Base Malignancies

This document was uploaded by one of our users. The uploader already confirmed that they had the permission to publish it. If you are author/publisher or own the copyright of this documents, please report to us by using this DMCA report form.

Download
Search on Amazon

Simply click on the Download Book button.

Yes, Book downloads on Ebookily are 100% Free.

Sometimes the book is free on Amazon As well, so go ahead and hit "Search on Amazon"

This book reviews the standard surgical, radiotherapeutic, and systemic management of sinonasal and skull base tumors. It provides up-to-date information on epidemiology, diagnostic modalities, molecular biology, staging, treatment complications, principles of supportive care, and current controversies. Sinonasal and skull base tumors display histologic and anatomic heterogeneity, as well as wide variation in clinical behavior. Accordingly, they pose significant diagnostic and treatment challenges. A multidisciplinary approach offers the best chance of a successful outcome. In addition to documenting in detail the currently accepted management approaches, this book sheds light on various promising novel therapeutic strategies. 

Sinonasal and Skull Base Malignancies is an invaluable reference for all specialists involved in treating these tumors, including otolaryngologists, head and neck surgeons, reconstructive surgeons, medical and radiation oncologists, neuroradiologists, specialized head and neck pathologists, prosthodontists, and speech and swallow therapists.

Author(s): Nabil F. Saba, Derrick T. Lin
Publisher: Springer
Year: 2022

Language: English
Pages: 282
City: Cham

Preface
Acknowledgment
Contents
Contributors
Chapter 1: The Etiology and Epidemiology of Sinonasal Malignancies
Introduction
Squamous Cell Carcinoma
Sinonasal
Nasopharyngeal
Adenocarcinoma
Adenoid Cystic Carcinoma
Olfactory Neuroblastoma
Sinonasal Neuroendocrine Carcinoma
Sinonasal Undifferentiated Carcinoma
Sinonasal Melanoma
Chordoma
Sarcoma
Rhabdomyosarcoma
Chondrosarcoma
Ewing’s Sarcoma
Lymphoma
NK/T-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
HPV-Related Multiphenotypic Sinonasal Carcinoma
References
Chapter 2: Radiology and Diagnostic Approaches to Sinonasal Malignancies and Skull Base Tumors
Introduction
Nasal Endoscopy and Biopsy
Computed Tomography
Computed Tomography Angiography
Magnetic Resonance Imaging
Positron Emission Tomography
PET/CT
PET/MRI
Interventional Neuroradiology
Image-Guided Surgery
References
Chapter 3: The Pathology of Common Sinonasal and Skull Base Malignancies
Introduction
Squamous Cell Carcinomas
Definition and Clinical Background
Pathology
Treatment and Prognosis
Non-salivary Sinonasal Adenocarcinoma
Definition and Clinical Background
Pathology
Treatment and Prognosis
Adenoid Cystic Carcinoma
Definition and Clinical Background
Pathology
Treatment and Prognosis
Mucosal Melanoma
Definition and Clinical Background
Pathology
Treatment and Prognosis
Olfactory Neuroblastoma
Definition and Clinical Background
Pathology
Treatment and Prognosis
Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Definition and Clinical Background
Pathology
Treatment and Prognosis
Rhabdomyosarcoma
Definition and Clinical Background
Pathology
Treatment and Prognosis
Extranodal NK-/T-Cell Lymphoma (ENKTL)
Definition and Clinical Background
Pathology
Treatment and Prognosis
Sinonasal Undifferentiated Carcinoma (SNUC)
Definition and Clinical Background
Pathology
Treatment and Prognosis
References
Chapter 4: Open Approaches to Sinonasal Tumors
Introduction
Approaches to the Maxillary Sinus: Caldwell-Luc Procedure/Approach
History
Technique: Caldwell-Luc Approach
Complications of Caldwell-Luc Approach
Denker Approach
Maxillectomy
History/Background
Technique: Weber-Ferguson Approach
Orbital Exenteration
Complications
Approaches to the Frontal and Ethmoid Sinuses
History
Technique: Lynch External Frontoethmoidectomy
Transorbital Approaches
Precaruncular Approach
Superior Eyelid Crease Approach
Technique: Osteoplastic Flap
Complications
Approaches to the Infratemporal Fossa (ITF) and Nasopharynx
History/Background
Preauricular-Subtemporal Approach
Maxillary Swing
Craniofacial Resection/Transcranial Approaches
History/Background
Extended Frontal Approach
Extended Frontal Approach Complications
Modified Orbitozygomatic Craniotomy
Facial Translocation
Complications of Facial Translocation
Conclusion
References
Chapter 5: Reconstruction and Rehabilitation After Surgical Ablation of the Paranasal Sinuses
Introduction
Defect Analysis
Approaches to Rehabilitation and Reconstruction
Prosthetic Rehabilitation
Skull Base Reconstruction
Palate Reconstruction
Maxillectomy Without Orbital Exenteration
With Orbital Floor Preservation
With Orbital Floor Resection
Maxillectomy with Orbital Exenteration
Special Considerations
Summary
References
Chapter 6: Endoscopic Resection of Sinonasal Tumors
Introduction
Resection of Skull Base Malignances: General Principles
Advantages of an Endoscopic Approach
Limitations of an Endoscopic Approach
Approaches
Open Craniofacial Resection of Sinonasal Malignancy: Outcomes
Endoscopic Approaches for Sinonasal Malignancy: Outcomes
Endoscopic Versus Open Approaches for Sinonasal Malignancy: Outcomes
Endoscopic Approaches to Specific Sinonasal Malignancies: Outcomes
Conclusion
References
Chapter 7: Endoscopic Reconstruction of the Skull Base
Introduction
Goals of Endoscopic Skull Base Reconstruction
Inlay/Onlay Grafts
Free Mucosal Grafts
Pedicled Vascularized Intranasal Flaps
Regional Extranasal Pedicled Flaps
Reconstructive Algorithm
Postoperative CSF Leak
Free Tissue Transfer
Conclusion
References
Chapter 8: Radiation Therapy for Sinonasal and Skull Base Tumors
Overview of Radiotherapy for Sinonasal and Skull Base Tumors
Data for Radiation by Histology
Squamous Cell Carcinoma
Nasal Vestibule Squamous Cell Carcinoma
Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
Key Points for Squamous Cell Carcinomas
Adenoid Cystic Carcinoma
Key Points for Adenoid Cystic Carcinoma
Esthesioneuroblastoma
Key Points for Esthesioneuroblastoma
Sinonasal Undifferentiated Carcinoma
Key Points for Sinonasal Undifferentiated Carcinoma
Sinonasal Neuroendocrine Carcinomas
Key Points for Sinonasal Neuroendocrine Carcinoma
Skull Base Chordomas and Chondrosarcomas
Chordomas
Chondrosarcomas
Key Points for Skull Base Chordomas and Chondrosarcomas
Sinonasal Mucosal Melanoma
Key Points for Sinonasal Mucosal Melanoma
Paragangliomas
Key Points for Paragangliomas
Radiotherapy Modalities
Intensity-Modulated Radiation Therapy
Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy
Charged Particle Therapy
Radiation Target Volumes
Treatment Volumes for Postoperative Radiation
Treatment Volumes for Intact Disease
Treatment Volumes After Induction Chemotherapy
Specific Considerations
Skin Involvement
Perineural Invasion
Supportive Care Measures and Toxicities
Sinonasal Mucositis
Oral Mucositis
Xerostomia
Ototoxicity
Visual Toxicity
Brain Radiation Necrosis
Endocrine Dysfunction
References
Chapter 9: The Role of Systemic Therapy and Targeted Approaches for the Treatment of Sinonasal Malignancies
Neoadjuvant or Induction Therapy
Adjuvant Systemic Therapies
Targeted Therapies and Immunotherapy
Systemic Therapy in Different Histotypes
Intestinal-Type Adenocarcinoma
Sinonasal Undifferentiated Carcinoma
Sinonasal Neuroendocrine Carcinoma
Olfactory Neuroblastoma (Esthesioneuroblastoma)
Sinonasal Primary Mucosal Melanomas
Sarcoma and Lymphoma
Sarcomas
Lymphomas
Conclusion
References
Chapter 10: Complications of Surgical Management of Skull Base and Sinonasal Malignancies
Introduction
Intraoperative Complications
Injury to Major Neurovascular Structures
Postoperative Complications
Pneumocephalus
Cerebrospinal Fluid Leak
Infection
Orbital Complications
Delayed Complications
Orbital Complications
Chronic Rhinosinusitis
Mucocele
Smell and Taste Disturbance
Wound Healing
Conclusion
References
Chapter 11: Supportive Care for Patients with Sinonasal and Skull Base Tumors
Introduction
Skull Base–Specific Patient-Reported Outcome (PRO) Instruments
Swallowing
Neuroanatomy and Physiology
Dysphagia Outcomes
Trigeminal Nerve (V)
Facial Nerve (VII)
Glossopharyngeal Nerve (IX)
Vagus Nerve (X)
Hypoglossal Nerve (CNXII)
Evaluation
Clinical Swallowing Evaluation
Modified Barium Swallow Study
Fiberoptic Endoscopic Evaluation of Swallowing
Patient-Reported Outcome Measures of Dysphagia
Dysphagia Rehabilitation
Voice
Neuroanatomy and Physiology
Voice Outcomes
Voice Evaluation
Vocal Rehabilitation
Speech
Neuroanatomy and Physiology
Dysarthria Outcomes
Speech Evaluation
Speech Rehabilitation
Cognitive-Communication
Neuroanatomy and Physiology
Cognitive-Communication Impairment Outcomes
Cognitive-Communication Evaluation
Cognitive-Communication Rehabilitation
Lymphedema
Lymphatic System
Lymphedema
Lymphedema Evaluation
Lymphedema Treatment
Lymphedema Case Examples in Sinonasal Malignancy
Summary
References
Chapter 12: Rare Sinonasal and Skull Base Tumors
Teratocarcinosarcoma
Biphenotypic Sinonasal Sarcoma
Chondrosarcoma
Chordoma
NUT Carcinoma (Nuclear Protein in Testis)
SMARCB1 (INI-1)-Deficient Carcinoma
HPV-Related Multiphenotypic Sinonasal Carcinoma
Sinonasal Neuroendocrine Carcinoma
Sinonasal Renal Cell-Like Adenocarcinoma
References
Correction to: Supportive Care for Patients with Sinonasal and Skull Base Tumors
Correction to:
Index