Scent and Chemistry: The Molecular World of Odor

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This book is the long awaited completely revised and extended edition of Günther Ohloff's standard work "Scent and Fragrances: The Fascination of Odors and Their Chemical Perspectives". The prominent chemists Günther Ohloff, Wilhelm Pickenhagen, and Philip Kraft convey the scientist, the perfumer, as well as the interested layman with a vivid and up-to-date picture of the state of the art of the chemistry of odorants and the research in odor perception. The book details on the molecular basis of olfaction, olfactory characterization of perfumery materials, structure-odor relationships, the chemical synthesis of odorants, and the chemistry of essential oils and odorants from the animal kingdom, backed up by ca. 400 perfumery examples and historical aspects. It will serve as a thorough introductory text for all those interested in the molecular world of odors. This book is written for everyone who wants to know more about the molecular basis of odor, and the relationships between chemical structures and olfactory properties. The great structural diversity of odorants, their synthesis, natural occurrence and their structure?odor correlation demonstrate what a fascinating science Fragrance Chemistry indeed is.

Author(s): Günther Ohloff, Philip Kraft, Wilhelm Pickenhagen
Edition: 2
Publisher: Wiley-VCH
Year: 2022

Language: English
Pages: 438
City: Hoboken

Cover
Title Page
Copyright
Contents
Chemical Foreword
Perfumistic Foreword: Synthetics or Naturals?
Preface to the Second Edition
Preface to the First Edition
Chapter 1 Historical Aspects
1.1 Scents of Time
1.2 Chemical Discoveries and Modern Perfumery
References
Chapter 2 The Chemical Senses
2.1 Anatomy, Physiology, and Biochemistry of Olfactory Receptors
2.2 Description and Classification of Odor Impressions
2.3 Quantitative Odor Perception
2.4 Glossary
References
Chapter 3 Structure–Odor Relationships
3.1 Physicochemical Properties of Odorants and the Concept of Osmophoric Groups
3.2 Structure–Odor Correlations
3.3 Molecular Shape and Odor: The Early Theories
3.4 The Concept of Profile and Bulky Groups
3.5 Unsaturated Compounds
3.6 Diastereoisomers
3.7 Steroid‐Type Odorants
3.8 Odor Rules
3.9 Bifunctional Units: Muguet and Caramel Odorants
3.10 QSAR: Homology Versus Olfactophore Models
3.11 Enantioselectivity of Odor Sensation
References
Chapter 4 Odorants from Natural Resources
4.1 Important Terpene Building Blocks
4.2 Odorants from α‐ and β‐Pinene
4.3 Synthetic Odorants from Cyclic Monoterpenes
4.4 Acyclic Odorants of the Monoterpene Series
4.5 Odorants from 3,7‐Dimethylocta‐1,6‐diene
4.6 Odorants by Functionalization of Myrcene
4.7 Odorants from (−)‐Caryophyllene and (+)‐Longifolene
4.8 Odorants from α‐Cedrene and Thujopsene
References
Chapter 5 Odorants from Petrochemical Sources
5.1 Isoprene as Starting Material for the Synthesis of Odorants
5.2 Isobutene and 3‐Methylbut‐1‐en‐2‐ol as Starting Materials
5.3 Terpenoids from Isobutene
5.4 (−)‐Menthol
References
Chapter 6 Ionones, Damascones, and Iso E Super
6.1 Violet and Orris Odorants
6.2 Rose Ketones
6.3 Isocyclemones
6.4 Ionone‐Type Materials in Perfumery
References
Chapter 7 Essential Oils
7.1 Citrus Oils
7.2 Petitgrain Oil
7.3 Neroli Oil/Orange Blossoms
7.4 Lavender Oil
7.5 Clary Sage Oil
7.6 Patchouli Oil
7.7 Jasmin Absolute
7.8 Rose Oil
7.9 Geranium Oil
7.10 Violet Oil
7.11 Orris Oil
7.12 Osmanthus Oil
7.13 Vetiver Oil
7.14 Cedarwood Oil
7.15 Sandalwood Oil
7.16 Galbanum
7.17 Labdanum
7.18 Oakmoss
7.19 Incense and Myrrh
7.20 Black and Pink Pepper
References
Chapter 8 Odorants of Animal Origin
8.1 Musk and Civet
8.2 Industrial Synthesis of Macrocyclic Odorants
8.3 Nonnatural Musks
8.4 Ambergris
8.5 Castoreum
References
Chapter 9 Composition and Creativity: A Simple Guide to Learning Perfumery
9.1 Basic Motivation
9.2 Getting Started
9.3 Studies in Raw Materials: The Alphabet of Odors
9.4 Basic Accords
9.5 Study of Archetypical Schemes
9.6 The Composition of a Fragrance
References
Subject Index
Perfume Index
EULA