Rhodopsin and G-protein Linked Receptors

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The quantity of information available about membrane proteins is now too large for any one person to be familiar with anything but a very small part of the primary literature. A series of volumes concentrating on molecular aspects of biological membranes therefore seems timely. The hope is that, when complete, these volumes will provide a convenient introduction to the study of a wide range of membrane functions. Application of the techniques of molecular biology has provided the sequences of a very large number of membrane proteins, and has led to the discovery of superfamilies of membrane proteins of related structure. The classic example of the superfamily is the seven helix receptor superfamily, all related in structure to bacteriorhodpsin, and named after the seven trans-membrane a-helices identified in bacteriorhodpsin. This volume explores the structures and functions of this super family.

Author(s): A.G. Lee (Eds.)
Series: Biomembranes: A Multi-Volume Treatise 2
Publisher: Elsevier Science
Year: 1996

Language: English
Pages: 1-503

Content:
List of contributors
Pages ix-xi

Preface
Page xiii
A.G. Lee

Rhodopsin structure and function Original Research Article
Pages 1-32
Burton J. Litman, Drake C. Mitchell

Characterization of the primary photochemical events in bacteriorhodopsin and rhodopsin Original Research Article
Pages 33-139
Jeffrey A. Stuart, Robert R. Birge

Light-induced protein-protein interactions on the rod photoreceptor disc membrane Original Research Article
Pages 141-198
Klaus Peter Hofmann, Martin Heck

Microbial sensory rhodopsins Original Research Article
Pages 199-226
John L. Spudich, David N. Zacks

Alpha-adrenergic receptors Original Research Article
Pages 227-244
David B. Bylund

List of contributors
Pages ix-xi

Preface
Page xiii
A.G. Lee

β-Adrenergic receptors Original Research Article
Pages 245-279
Susan M. Pellegrino, Norman H. Lee, Claire M. Fraser

G protein-coupled serotonin receptors Original Research Article
Pages 281-300
Jean C. Shih, Timothy K. Gallaher

The muscarinic acetylcholine receptors Original Research Article
Pages 301-320
Petra Högger, Wolfgang Sadée, Jelveh Lameh

Adenosine receptors Original Research Article
Pages 321-347
David R. Luthin, John A. Auchampach, Joel Linden

Metabotropic glutamate receptors Original Research Article
Pages 349-385
Patrick J. O'Hara

Glycoprotein hormone receptors: New molecular supports for old biological functions Original Research Article
Pages 387-462
Roland Salesse, Jean Gamier

Platelet activating factor receptor Original Research Article
Pages 463-479
Shivendra D. Shukla

Index
Pages 481-503