"Refer to the Red Book." That's been the watchword for generations of healthcare professionals seeking trustworthy guidance on pediatric infectious disease prevention, management, and control. Now the 32nd edition continues this tradition of excellence with the latest clinical guidance on manifestations, etiology, epidemiology, diagnosis and treatment of more than 200 childhood infectious diseases.
The 32nd edition provides evidence-based guidance on pediatric infections and vaccinations based on the recommendations of the committee as well as the combined expertise of the CDC, the FDA and hundreds of contributors.
Red Book is an indispensable reference for pediatricians and pediatric infectious disease specialists and is useful for family medicine and emergency medicine physicians, as well. Public health and school health professionals, medical residents, and students also will find it a high-yield source of pediatric infectious disease and vaccine information.
New in the 2021 Red Book
All chapters were assessed for relevance in the dynamic environment that is the practice of medicine today, and every chapter has been modified.
Two chapters have been added to the 2021 edition: Pseudomonas aeruginosa Infections and a new "System-Based Treatment" table designed to aid in initial antibiotic selections by clinical conditions.
Standardized approaches to disease prevention through immunizations, antimicrobial prophylaxis, and infection-control practices have been updated throughout the Red Book
References to evidence-based policy recommendations have been updated throughout the Red Book.
Appropriate chapters throughout the Red Book have been updated to be consistent with 2021 AAP and CDC vaccine recommendations for immunization of health care personnel, and drug recommendations from 2021 Nelson's Pediatric Antimicrobial Therapy.
Author(s): American Academy of Pediatrics, David W. Kimberlin, Elizabeth D. Barnett, Ruth Lynfield, Mark H. Sawyer
Edition: 32
Publisher: American Academy of Pediatrics
Year: 2021
Language: English
Commentary: TRUE PDF
Tags: Infectious Diseases; Pediatrics; Pediatric Infectious Diseases
Summary of Major Changes in the 2021 Red Book
Section 1: Active and Passive Immunization
Prologue
Sources of Information About Immunization
Discussing Vaccines With Patients and Parents
Addressing Parents’ Questions About Vaccine Safety and Effectiveness
Common Misconceptions About Immunizations
Resources for Optimizing Communications With Parents About Vaccines
Parental Refusal of Immunizations
Immunization Documentation
Active Immunization
Vaccine Ingredients
Vaccine Handling and Storage
Vaccine Administration
Managing Injection Pain
Immunization Schedule and Timing of Vaccines
Minimum Ages and Minimum Intervals Between Vaccine Doses
Interchangeability of Vaccine Products
Simultaneous Administration of Multiple Vaccines
Combination Vaccines
Lapsed Immunizations
Unknown or Uncertain Immunization Status
Vaccine Dose
Active Immunization After Receipt of Immune Globulin or Other Blood Products
Vaccine Safety
Risks and Adverse Events
National Academy of Medicine Reviews of Adverse Events After Immunization
Immunization Safety Review
Childhood Immunization Schedule and Safety
Vaccine Adverse Event Reporting System
Vaccine Safety Datalink Project
FDA CBER Sentinel Program
Clinical Immunization Safety Assessment (CISA) Project
Vaccine Injury Compensation
Hypersensitivity Reactions After Immunization
Immediate-Type Allergic Reactions
Delayed-Type Allergic Reactions
Other Vaccine Reactions
Passive Immunization
Immune Globulin Intramuscular (IGIM)
Immune Globulin Intravenous (IGIV)
Immune Globulin Subcutaneous (IGSC)
Treatment of Anaphylactic Reactions
Immunization in Special Clinical Circumstances
Immunization in Preterm and Low Birth Weight Infants
Immunization in Pregnancy
Immunization and Other Considerations in Immunocompromised Children
Immunization in Children With a Personal or Family History of Seizures
Immunization in Children With Chronic Diseases
Immunization in American Indian/Alaska Native Childrenand Adolescents
Immunization in Adolescent and College Populations
Immunization in Health Care Personnel
Children Who Received Immunizations Outside the United States or Whose Immunization Status is Unknown or Uncertain
International Travel
Section 2: Recommendations for Care of Children in Special Circumstances
Breastfeeding and Human Milk
AAP Recommendations on Breastfeeding
Contraindications to Breastfeeding
Immunization of Mothers and Infants
Transmission of Infectious Agents via Human Milk
Antimicrobial Agents and Other Drugs in Human Milk
Anti-TNF Biologic Response Modifiers in Human Milk
Children in Group Child Care and Schools
Modes of Spread of Infectious Diseases
Respiratory Tract Diseases
Enteric Diseases
Bloodborne Infections
Other Infections
Management and Prevention of Infectious Diseases
Immunization
Infection Control and Prevention
Exclusion and Return to Care
Infection Prevention and Control for Hospitalized Children
Infection Prevention and Control Precautions
Strategies to Prevent Health Care-Associated Infections
Occupational Health
Sibling Visitation
Adult Visitation
Pet Visitation
Infection Prevention and Control in Ambulatory Settings
Sexually Transmitted Infections in Adolescents and Children
STIs During Preventive Health Care of Adolescents
Sexual Assault and Abuse in Children and Adolescents/Young Adults
Medical Evaluation for Infectious Diseases for Internationally Adopted, Refugee, and Immigrant Children
Consideration for Testing for Infectious Agents
Hepatitis A
Hepatitis B
Hepatitis C
Intestinal Pathogens
Tissue Parasites/Eosinophilia
Sexually Transmitted Infections
Tuberculosis
HIV Infection
Chagas Disease (American Trypanosomiasis)
Other Infectious Diseases
Injuries From Needles Discarded in the Community
Wound Care and Tetanus Prophylaxis
Bloodborne Pathogens
Preventing Needlestick Injuries
Bite Wounds
Prevention of Mosquitoborne and Tickborne Infections
General Protective Measures
Repellents for Use on Skin
Tick Inspection and Removal
Other Preventive Measures
Prevention of Illnesses Associated with Recreational Water Use
Section 3: Summaries of Infectious Diseases
Actinomycosis
Adenovirus Infections
Amebiasis
Amebic Meningoencephalitis and Keratitis
Anthrax
Arboviruses
Arcanobacterium haemolyticum Infections
Ascaris lumbricoides Infections
Aspergillosis
Astrovirus Infections
Babesiosis
Bacillus cereus Infections and Intoxications
Bacterial Vaginosis
Bacteroides, Prevotella, and Other Anaerobic Gram-NegativeBacilli Infections
Balantidium coli Infections (Balantidiasis)
Bartonella henselae (Cat-Scratch Disease)
Baylisascaris Infections
Infections With Blastocystis Species
Blastomycosis
Bocavirus
Borrelia Infections Other Than Lyme Disease (Relapsing Fever)
Brucellosis
Burkholderia Infections
Campylobacter Infections
Candidiasis
Chancroid and Cutaneous Ulcers
Chikungunya
Chlamydial Infections
Chlamydia pneumoniae
Chlamydia psittaci (Psittacosis, Ornithosis, Parrot Fever)
Chlamydia trachomatis
Clostridial Infec
Botulism and Infant Botulism (Clostridium botulinum)
Clostridial Myonecrosis (Gas Gangrene)
Clostridioides difficile (formerly Clostridium difficile)
Clostridium perfringens Foodborne Illness
Coccidioidomycosis
Coronaviruses, Including SARS-CoV-2 and MERS-CoV
Cryptococcus neoformans and Cryptococcus gattii Infections (Cryptococcosis)
Cryptosporidiosis
Cutaneous Larva Migrans
Cyclosporiasis
Cystoisosporiasis (formerly Isosporiasis)
Cytomegalovirus Infection
Dengue
Diphtheria
Ehrlichia, Anaplasma, and Related Infections (Human Ehrlichiosis, Anaplasmosis, and Related Infections Attributable to Bacteria in the Family Anaplasmataceae)
Serious Neonatal Bacterial Infections Caused by Enterobacteriaceae (Including Septicemia and Meningitis)
Enterovirus (Nonpoliovirus) (Group A and B Coxsackieviruses, Echoviruses, Numbered Enteroviruses)
Epstein-Barr Virus Infections (Infectious Mononucleosis)
Escherichia coli Diarrhea (Including Hemolytic-Uremic Syndrome)
Other Fungal Diseases
Fusobacterium Infections (Including Lemierre Syndrome)
Giardia duodenalis (formerly Giardia lamblia and Giardia intestinalis) Infections (Giardiasis)
Gonococcal Infections
Granuloma Inguinale (Donovanosis)
Haemophilus influenzae Infections
Hantavirus Pulmonary Syndrome
Helicobacter pylori Infections
Hemorrhagic Fevers Caused by Arenaviruses
Hemorrhagic Fevers Caused by Bunyaviruses
Hemorrhagic Fevers Caused by Filoviruses: Ebola and Marburg
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Herpes Simplex
Histoplasmosis
Hookworm Infections (Ancylostoma duodenale and Necator americanus)
Human Herpesvirus 6 (Including Roseola) and 7
Human Herpesvirus 8
Human Immunodeficiency Virus Infection
Human Papillomaviruses
Influenza
Kawasaki Disease
Kingella kingae Infections
Legionella pneumophila Infections
Leishmaniasis
Leprosy
Leptospirosis
Listeria monocytogenes Infections (Listeriosis)
Lyme Disease (Lyme Borreliosis, Borrelia burgdorferi sensu lato Infection)
Lymphatic Filariasis (Bancroftian, Malayan, and Timorian)
Lymphocytic Choriomeningitis Virus
Malaria
Measles
Meningococcal Infections
Human Metapneumovirus
Microsporidia Infections (Microsporidiosis)
Molluscum Contagiosum
Moraxella catarrhalis Infections
Mumps
Mycoplasma pneumoniae and Other Mycoplasma Species Infections
Nocardiosis
Norovirus and Sapovirus Infections
Onchocerciasis (River Blindness, Filariasis)
Paracoccidioidomycosis (Formerly Known as South American Blastomycosis)
Paragonimiasis
Parainfluenza Viral Infections
Parasitic Diseases
Parechovirus Infections
Parvovirus B19 (Erythema Infectiosum, Fifth Disease)
Pasteurella Infections
Pediculosis Capitis (Head Lice)
Pediculosis Corporis (Body Lice)
Pediculosis Pubis (Pubic Lice, Crab Lice)
Pelvic Inflammatory Disease
Pertussis (Whooping Cough)
Pinworm Infection (Enterobius vermicularis)
Pityriasis Versicolor (Formerly Tinea Versicolor)
Plague
Pneumocystis jirovecii Infections
Poliovirus Infections
Polyomaviruses (BK, JC, and Other Polyomaviruses)
Prion Diseases: Transmissible Spongiform Encephalopathies
Pseudomonas aeruginosa Infections
Q Fever (Coxiella burnetii Infection)
Rabies
Rat-Bite Fever
Respiratory Syncytial Virus
Rhinovirus Infections
Rickettsial Diseases
Rickettsialpox
Rocky Mountain Spotted Fever
Rotavirus Infections
Rubella
Salmonella Infections
Scabies
Schistosomiasis
Shigella Infections
Smallpox (Variola)
Sporotrichosis
Staphylococcal Food Poisoning
Staphylococcus aureus
Coagulase-Negative Staphylococcal Infections
Group A Streptococcal Infections
Group B Streptococcal Infections
Non-Group A or B Streptococcal and Enterococcal Infections
Streptococcus pneumoniae (Pneumococcal) Infections
Strongyloidiasis (Strongyloides stercoralis)
Syphilis
Tapeworm Diseases (Taeniasis and Cysticercosis)
Other Tapeworm Infections (Including Hydatid Disease)
Tetanus (Lockjaw)
Tinea Capitis (Ringworm of the Scalp)
Tinea Corporis (Ringworm of the Body)
Tinea Cruris (Jock Itch)
Tinea Pedis and Tinea Unguium (Onychomycosis) (Athlete’s Foot, Ringworm of the Feet)
Toxocariasis
Toxoplasma gondii Infections (Toxoplasmosis)
Trichinellosis (Trichinella spiralis and Other Species)
Trichomonas vaginalis Infections (Trichomoniasis)
Trichuriasis (Whipworm Infection)
African Trypanosomiasis (African Sleeping Sickness)
American Trypanosomiasis (Chagas Disease)
Tuberculosis
Nontuberculous Mycobacteria (Environmental Mycobacteria, Mycobacteria other than Mycobacterium tuberculosis)
Tularemia
Louseborne Typhus (Epidemic or Sylvatic Typhus)
Murine Typhus (Endemic or Fleaborne Typhus)
Ureaplasma urealyticum and Ureaplasma parvum Infections
Varicella-Zoster Virus Infections
Vibrio Infections
Cholera (Vibrio cholerae)
Other Vibrio Infections
West Nile Virus
Yersinia enterocolitica and Yersinia pseudotuberculosis Infections (Enteritis and Other Illnesses)
Zika
Section 4: Antimicrobial Agents and Related Therapy
Introduction
Fluoroquinolones
Tetracyclines
Antimicrobial Agents Approved for Use in Adults but Not Children
Cephalosporin Cross-Reactivity With Other Beta Lactam Antibiotics
Antimicrobial Resistance and Antimicrobial Stewardship:Appropriate and Judicious Use of Antimicrobial Agents
Antimicrobial Resistance
Factors Contributing to Resistance
Actions to Prevent or Slow Antimicrobial Resistance
Antimicrobial Stewardship
Role of the Medical Provider
Principles of Appropriate Use of Antimicrobial Therapy for Upper Respiratory Tract Infections
Drug Interactions
Tables of Antibacterial Drug Dosages
Sexually Transmitted Infections
Antifungal Drugs for Systemic Fungal Infections
Polyenes
Pyrimidines
Azoles
Echinocandins
Recommended Doses of Parenteral and Oral Antifungal Drugs
Topical Drugs for Superficial Fungal Infections
Non-HIV Antiviral Drugs
Drugs for Parasitic Infections
Systems-based Treatment Table
MedWatch—The FDA Safety Information and Adverse Event-Reporting Program
Section 5: Antimicrobial Prophylaxis
Antimicrobial Prophylaxis
Infection-Prone Body Sites
Exposure to Specific Pathogens
Vulnerable Hosts
Antimicrobial Prophylaxis in Pediatric Surgical Patients
Guidelines for Appropriate Use
Indications for Prophylaxis
Surgical Site Infection Criteria
Timing of Administration of Prophylactic Antimicrobial Agents
Dosing and Duration of Administration of Antimicrobial Agents
Preoperative Screening and Decolonization
Recommended Antimicrobial Agents
Prevention of Bacterial Endocarditis
Neonatal Ophthalmia
Primary Prevention
Secondary Prevention
Legal Mandates for Topical Prophylaxis for Neonatal Ophthalmia
Pseudomonal Ophthalmia
Other Nongonococcal, Nonchlamydial Ophthalmia
Appendices
I. Directory of Resources
II. Codes for Commonly Administered Pediatric Vaccines/Toxoids and Immune Globulins
III. Nationally Notifiable Infectious Diseases in the United States
IV. Guide to Contraindications and Precautions to Immunizations
V. Prevention of Infectious Disease From Contaminated Food Products
VI. Clinical Syndromes Associated With Foodborne Diseases
VII. Diseases Transmitted by Animals (Zoonoses)
Index
