Rectal Cancer Treatment (Recent Results in Cancer Research)

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Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.

Author(s): M.W. Buchler (Editor), R. J. Heald (Editor), B. Ulrich (Editor), J. Weitz (Editor)
Edition: 1
Year: 2005

Language: English
Pages: 276

Contents......Page 5
Postoperative Pathophysiology and Choice of Incision......Page 8
Fast-Track Colonic Surgery: Status and Perspectives......Page 15
Fast-Track Surgery: The Heidelberg Experience......Page 21
Rectal Cancer: A Compartmental Disease. The Mesorectum and Mesorectal Lymph Nodes......Page 28
The Pathological Assessment of Total Mesorectal Excision: What Are the Relevant Resection Margins?......Page 37
Is the Lateral Lymph Node Compartment Relevant?......Page 47
Diagnostics of Rectal Cancer: Endorectal Ultrasound......Page 53
Preoperative Staging of Rectal Cancer: The MERCURY Research Project......Page 65
Rectal Cancer Management: Europe Is Ahead......Page 82
Teaching Efforts to Spread TME Surgery in Sweden......Page 89
Learning Curve: The Surgeon as a Prognostic Factor in Colorectal Cancer Surgery......Page 93
Surgical Results of Total Mesorectal Excision for Rectal Cancer in a Specialised Colorectal Unit......Page 112
Total Mesorectal Excision: The Heidelberg Results after TME......Page 119
Is Local Excision of T2/T3 Rectal Cancers Adequate?......Page 127
Operative Treatment of Locally Recurrent Rectal Cancer......Page 143
Laparoscopic TME: Better Vision, Better Results?......Page 155
Laparoscopic TME–The Surgeon’s or the Patient’s Preference......Page 165
Laparoscopic Total Mesorectal Excision–The Turin Experience......Page 174
Evacuation of Neorectal Reservoirs after TME......Page 187
Long-Term Functional Results After Straight or Colonic J-Pouch Coloanal Anastomosis......Page 198
Urinary and Sexual Function After Total Mesorectal Excision......Page 203
Functional Results of the Colon J-Pouch Versus Transverse Coloplasty Pouch in Heidelberg......Page 212
Indications for Neoadjuvant Long-Term Radiotherapy......Page 219
Neoadjuvant Radiotherapy and Radiochemotherapy for Rectal Cancer......Page 228
Adjuvant Radiochemotherapy for Rectal Cancer......Page 238
Intraoperative Radiotherapy for Rectal Carcinoma......Page 245
Indications and Effect on Survival of Standard Chemotherapy in Advanced Colorectal Cancer......Page 252
New Chemotherapeutic Strategies in Colorectal Cancer......Page 257
Active Specific Immunotherapy in Colon Cancer......Page 267
Radiofrequency Ablation in Metastatic Disease......Page 275