This book presents a collection of high-quality research papers, presented at the Second International Symposium on Bioinformatics and Biomedicine (BioInfoMed’2022). It offers a comprehensive look into some of the fastest growing fields of science, such as biomedicine, bioinformatics, artificial intelligence, and mathematical modeling. The different chapters of the work include both practical solutions and strictly scientific considerations expanding knowledge about the future bioinformatics and biomedical engineering challenges. We believe that the presented works will have a great impact not only on the development and the application of new methods for modeling, decision making and data mining in healthcare and biomedicine, but also it will provide a source of inspiration for researchers who can implement the proposed methods into their practice and scientific studies.
Author(s): Sotir Sotirov, Tania Pencheva, Janusz Kacprzyk, Krassimir T. Atanassov, Evdokia Sotirova, Simeon Ribagin
Series: Lecture Notes in Networks and Systems, 658
Publisher: Springer
Year: 2023
Language: English
Pages: 309
City: Cham
Preface
Contents
Data Mining in Biomedicine and Healthcare
Rhythm Analysis During Cardio-Pulmonary Resuscitation with Convolutional and Recurrent Neural Networks Using ECG and Optional Impedance Input
1 Introduction
2 Database
3 Methods
3.1 DNN Model Design
3.2 DNN Model Training
3.3 Performance Evaluation
4 Results and Discussion
5 Conclusions
References
Parallel Technique on Bidirectional Associative Memory Cohen-Grossberg Neural Network
1 Introduction
2 Mathematical Model
2.1 CUDA
2.2 OpenMPI
3 Results
References
Prediction of the Granulometric Composition of the Silt Loading on Transport Arteries in the City of Bourgas Based on Artificial Neural Networks
1 Introduction
2 Materials and Methods
3 Results and Discussion
4 Conclusions
References
Emotion Recognition Using Convolutional Neural Network
1 Introduction
1.1 Artificial Neural Networks
1.2 Convolutional Neural Networks
2 Results and Discussion
3 Conclusion
References
Water Safety and Toxicity Assessment Using Real Time Sensor Measurements and Fuzzy Logic Data Processing
1 Introduction
2 Experimental
2.1 Bio-electrochemical Sensor Construction and Operation
2.2 Microorganisms and Cultivation Conditions
2.3 Toxicity Detection
2.4 Fuzzy Logic Modelling
3 Results and Discussions
References
An Intuitionistic Fuzzy Estimation Approach on a Magnetic Resonance Imaging
1 Introduction
2 Image Acquisition
3 Fuzzy Estimation on the Image Quality
4 Conclusion
References
Bioinformatics and Biostatistical Models for Analysis and Prognosis of Antimicrobial Resistance
1 Introduction
2 Data and Methods of Analysis
3 Results
4 Discussion and Conclusions
References
Decision Making in Biomedicine and Healthcare
InterCriteria Analysis of Data Obtained from Patients with Hypercholesterolemia Treated with Linoprixol
1 Introduction
2 Results and Discussion
3 Conclusions
References
ABO System Blood Groups Distribution in Bulgaria, Based on a Dataset of the Patients of the University Hospital “Saint Anna”, Sofia, Bulgaria, from 2015 to 2021
1 Introduction
2 Materials and Methods
3 Results
4 Comparison with Previous Studies
5 Conclusions and Further Research
References
InterCriteria Analysis of the Geographic Distribution of the ABO System Blood Groups in the Patients of the University Hospital “Saint Anna”, Sofia, Bulgaria, from 2015 to 2021
1 Introduction
2 Materials and Methods
3 Results: Blood Group Distributions on Regional Level
4 Results: InterCriteria Analysis
5 Discussions and Conclusions
References
Comparison of Docking Scoring Functions by InterCriteria Analysis on a Set of Protein Targets Related to Alzheimer and Parkinson Diseases
1 Introduction
2 Materials and Methods
2.1 InterCriteria Analysis Approach
2.2 Protein Targets and Small Ligand Dataset
2.3 Molecular Docking
3 Results and Discussion
4 Conclusions
References
Multicriteria Analysis of Oncology Data During the Covid Pandemic
1 Introduction
2 Description of the Data
3 The ICA Approach
3.1 Applying the ICA Approach to a Data for Patients with Oncological Disease and Covid-19 Infection
3.2 Applying the ICA Approach to a Data for Medical Staff
4 Clustering of the Data
5 Conclusion
References
Biomedical Approaches and Applications
Convolutional Autoencoder for Filtering of Power-Line Interference with Variable Amplitude and Frequency: Study of 12-Lead PTB-XL ECG Database
1 Introduction
2 Materials and Methods
2.1 ECG Database
2.2 Convolutional Autoencoder Architecture
2.3 Deep Learning Strategy
2.4 Evaluation of Denoised Signal Quality
3 Results and Discussion
3.1 Training
3.2 Test 1: Constant PLI with Different ECG Leads
3.3 Test 1: Constant PLI with Different Input SNR
3.4 Test 2: Constant PLI with Different Frequencies
3.5 Test 3: Non-stationary PLI with Linearly Changing Amplitude
3.6 Test 4: Non-stationary PLI with Linearly Changing Frequency
4 Conclusions
References
Lipid Order of Membranes Isolated from Erythrocytes of Patients with Coronary Artery Disease: Correlation with Biochemical Parameters
1 Introduction
2 Materials and Methods
2.1 Patients
2.2 Blood Plasma and Erythrocyte Ghost Membranes Isolation
2.3 Determination of Lipid Packing in Erythrocyte Ghost Membranes
2.4 Fatty Acid Analysis of Erythrocyte Ghost Membrane and Blood Plasma
2.5 Statistical Analysis
3 Results and Discussion
4 Conclusions
References
Stress Response of Gram-Positive and Gram-Negative Bacteria Induced by Metal and Non-metal Nanoparticles. In Search of Smart Antimicrobial Agents
1 Introduction
2 Materials and Methods
2.1 Nanoparticles
2.2 Microorganisms
2.3 Antimicrobial Activity
3 Results and Discussion
4 Conclusions
References
Reactivity of Recombinant and Native pLDH Antigens with Seven Commercially Available Rapid Diagnostic Test Kits for Malaria Diagnosis
1 Introduction
2 Materials and Methods
2.1 Samples Used in This Study
2.2 Cultivation of Native P. falciparum and P. vivax
2.3 Testing Protocol Followed for Seven RDTs
2.4 Evaluation of RDTs Using Six Recombinant pLDH Antigens
2.5 Cultivation of Pf and Pv Parasites
2.6 Evaluation of RDTs Using Native pLDH Antigens
3 Discussion
4 Conclusions
References
Phytochemical Composition and Therapeutic Potential of Bistorta major Gray: A Review
1 Introduction
2 Phytochemical Composition
3 Pharmacological Activities
3.1 AqE
3.2 HAE and Other Extracts
4 Structure-Activity Relationship
5 Toxicological Aspects
6 Future Perspectives
7 Summary
References
Methods of Treatment of Congenital Deformities of the Musculoskeletal System: Talipes Equinovarus
1 Introduction
1.1 Definition
1.2 Etiology
1.3 Methods
2 Results
2.1 Prenatal Period
2.2 Postnatal Period
2.3 Surgical Intervention
2.4 Ponseti Method
2.5 Palliative Care
3 Discussion
4 Conclusion
References
Rehabilitation Approach After Arthroscopic Rotator Cuff Repair
1 Introduction
2 Material and Methods
3 Results and Discussion
4 Conclusions
References
3D Technologies in Urological Practice. Application of Software for 3D Processing in Urological Practice
1 Introduction
2 Materials and Methods
3 Results
4 Conclusion
References
Emotional Intelligence of Students During Pandemic Outbreak. A Study in Higher Education
1 Introduction
2 Methodology for Assessment the Dimensions of EI
3 Data Processing by Intuitionistic Fuzzy Sets
4 Evaluation of Student`s Emotional Intelligence
5 Conclusions
References
Mathematical Modelling in Biomedicine and Healthcare
Generalized Net Model of Rehabilitation Algorithm for Patients with Proximal Humeral Fracture After Surgical Treatment
1 Introduction
2 Material and Methods: The Apparatus of Generalized Nets
3 Results: The Generalized Net Model
4 Conclusions
References
Generalized Net Model of the Malignant Melanoma Treatment
1 Introduction
2 Materials and Methods
3 A Generalized Net Model of the Process of the Malignant Melanoma Treatment
4 Conclusion
References
Generalized Net Model of the Prostate Cancer Early Stages of Development
1 Introduction: Stages and Early Events in the Development of Prostate Cancer
2 The Generalized Net Model
3 Conclusion
References
Generalized Net Model of the Vegetative (Autonomic) Innervation of Gastrointestinal Tract
1 Introduction
2 A Generalized Net Model
3 Conclusion
References
Generalized Net Model of Density-Based Spatial Clustering of Applications with Noise (DBSCAN) Algorithm and Its Application on Diabetes Dataset
1 Brief Introduction on Generalized Nets (GNs) and Intuitionistic Fuzzy Sets (IFS)
2 Generalized Net Model of Density-Based Spatial Clustering of Applications with Noise (DBSCAN)
3 Results of the DBSCAN Implementation
4 Analysis of the Clusters from DBSCAN
5 Conclusion
References
Generalized Net Model of Multimodal Biometric System for Authenticating an Individual by Keystroke Dynamics and Eye Tracking Techniques
1 Behavioral Biometrics: Keystroke Dynamics and Eye Tracking
2 Generalized Net Model of Multimodal Biometric System Authenticating the Individual by Keystroke Dynamics and Eye Tracking Techniques
3 Conclusion
References
Generalized Net Model of the Consequences of Earthquake
1 Introduction
2 Literature Review
3 Generalised Nets
4 Generalized Net for Modeling Earthquake Consequences
5 Conclusion
References
A Generalized Net Model of Time-Delay Recurrent Neural Networks with the Stochastic Gradient Descent and Dropout Algorithm
1 Introduction
1.1 Remarks on Generalized Nets
2 Generalized Nets Model
3 Conclusions
References
Author Index