Rapid Characterization of Microorganisms by Mass Spectrometry

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Content: 1. RAPID CHARACTERIZATION OF MICROORGANISMS BY MASS SPECTROMETRY: AN OVERVIEW; CATHERINE FENSELAU AND PLAMEN DEMIREV; 2. RAPID SAMPLE PREPARATION FOR MICROORGANISM ANALYSIS BY MASS SPECTROMETRY; FRANCO BASILE; 3. DISCRIMINATION OF FUNGI BY MALDI-TOF MASS SPECTROMETRY; JUSTIN M. HETTICK, BRETT J. GREEN, AMANDA D. BUSKIRK, JAMES E. SLAVEN, MICHAEL L. KASHON, AND DONALD H. BEEZHOLD; 4. FUNGAL METABOLITES FOR MICROORGANISM CLASSIFICATION BY MASS SPECTROMETRY; VLADIMIR HAVLICEK AND KAREL LEMR; 5. RAPID PROFILING OF RECOMBINANT PROTEIN EXPRESSION FROM CRUDE CELL CULTURES BY MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY (MALDI-MS); SCOTT C. RUSSELL; 6. DETECTION, DIFFERENTIATION AND SUBTYPING OF BOTULINUM NEUROTOXINS IN CLINICAL SAMPLES WITH MASS SPECTROMETRY; JOHN R. BARR, SUZANNE R. KALB, AND JAMES L. PIRKLE; 7. RAPID IDENTIFICATION OF FOOD-BORNE PATHOGENS BY TOP-DOWN PROTEOMICS USING MALDI-TOF/TOF MASS SPECTROMETRY; CLIFTON K. FAGERQUIST; 8. TOP-DOWN PROTEIN ANALYSIS AND PHYLOGENETIC CHARACTERIZATION OF UNSEQUENCED BACTERIA; NATHAN J. EDWARDS, COLIN WYNNE, AVANTIKA DHABARIA, AND CATHERINE FENSELAU; 9. MATRIX ASSISTED LASER DESORPTION IONIZATION ION MOBILITY TIME-OF-FLIGHT MASS SPECTROMETRY OF BACTERIA; JUANEKA M. HAYES, LOUIS C. ANDERSON, J. ALBERT SCHULTZ, MICHAEL UGAROV, THOMAS F. EGAN, ERNEST K. LEWIS, VIRGINIA WOMACK, AMINA S. WOODS, SHELLEY N. JACKSON, ROBERT H. HAUGE, CARTER KITTRELL, STEVE RIPLEY, AND; KERMIT K. MURRAY; 10. SINGLE-PARTICLE AEROSOL MASS SPECTROMETRY (SPAMS) FOR HIGH-THROUGHPUT AND RAPID ANALYSIS OF BIOLOGICAL AEROSOLS AND SINGLE CELLS; MATTHIAS FRANK, ERIC E. GARD, HERBERT J. TOBIAS, KRISTL L. ADAMS, MICHAEL J. BOGAN, KEITH R. COFFEE, GEORGE R. FARQUAR, DAVID P. FERGENSON, SUE I. MARTIN, MAURICE PITESKY, VINCENT J. RIOT, ABNEESH SRIVASTAVA, PAUL T. STEELE, AND AUDREY M. WILLIAMS; 11. RAPID DETECTION AND IDENTIFICATION OF AEROSOLIZED BIOLOGICAL MATERIALS, TOXINS, AND MICROORGANISMS BY AN AP-MALDI-MS-BASED SYSTEM; BERK OKTEM, APPAVU K. SUNDARAM, JANE RAZUMOVSKAYA, SESHU K. GUDLAVALLETI, THOMAS D. SAUL, AND VLADIMIR M. DOROSHENKO; 12. MALDI MASS SPECTROMETRY FOR RAPID DETECTION AND CHARACTERIZATION OF BIOLOGICAL THREATS; NATHAN A. HAGAN, JEFFREY S. LIN, MIQUEL D. ANTOINE, TIMOTHY J. CORNISH, RACHEL S. QUIZON, BERNARD F. COLLINS, ANDREW B. FELDMAN, AND PLAMEN A. DEMIREV; EDITORS' BIOGRAPHIES; AUTHOR INDEX; SUBJECT INDEX

Author(s): Catherine Fenselau and Plamen Demirev (Eds.)
Series: ACS Symposium Series 1065
Publisher: American Chemical Society
Year: 2011

Language: English
Pages: 235
City: Washington, DC

Title......Page 1
Foreword......Page 5
1. Rapid Characterization of Microorganisms by Mass Spectrometry: An Overview......Page 6
2. Rapid Sample Preparation for Microorganism Analysis by Mass Spectrometry......Page 10
3. Discrimination of Fungi by MALDI-TOF Mass Spectrometry......Page 40
4. Fungal Metabolites for Microorganism Classification by Mass Spectrometry......Page 56
5. Rapid Profiling of Recombinant Protein Expression from Crude Cell Cultures by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS)......Page 66
6. Detection, Differentiation and Subtyping of Botulinum Neurotoxins in Clinical Samples with Mass Spectrometry......Page 87
7. Rapid Identification of Food-Borne Pathogens by Top-Down Proteomics Using MALDI-TOF/TOF Mass Spectrometry......Page 102
8. Top-Down Protein Analysis and Phylogenetic Characterization of Unsequenced Bacteria......Page 124
9. Matrix Assisted Laser Desorption Ionization Ion Mobility Time-of-Flight Mass Spectrometry of Bacteria......Page 146
10. Single-Particle Aerosol Mass Spectrometry (SPAMS) for High-Throughput and Rapid Analysis of Biological Aerosols and Single Cells......Page 164
11. Rapid Detection and Identification of Aerosolized Biological Materials, Toxins, and Microorganisms by an AP-MALDI-MS-Based System......Page 200
12. MALDI Mass Spectrometry for Rapid Detection and Characterization of Biological Threats......Page 214
Editors’ Biographies......Page 228
Subject Index......Page 229