Psychiatric Genetics: Applications in Clinical Practice

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Psychiatric Genetics is the first book to focus on clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, and the uses of genetic testing. Written explicitly for practitioners, it offers a clinically relevant resource to help readers interpret the often bewildering flood of information about genetics and to facilitate responding to patients requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues.

The book first presents a framework for understanding and critically evaluating psychiatric genetic research literature, then provides guidelines for genetic counseling. Subsequent chapters summarize genetic aspects of major psychiatric conditions from childhood-onset disorders through psychotic, mood, and anxiety disorders to dementia as well as neuropsychiatric manifestations of other genetic disorders. Risk/benefit considerations related to medication use during pregnancy are then presented. Coverage of ethical, legal, and social implications illustrates the dilemmas that arise with advances in genetic research. Whether used as a clinical guide, reference, or ancillary text, Psychiatric Genetics provides the most up-to-date source on the impact of this growing field on everyday psychiatric practice.

Author(s): Jordan W., M.D. Smoller, Jordan W., M.D. Smoller, Beth Rosen Sheidley, Ming T. Tsuang
Edition: 1
Publisher: American Psychiatric Publishing, Inc.
Year: 2008

Language: English
Pages: 338

Contents......Page 6
Contributors......Page 8
Preface......Page 12
Part 1: General Principles......Page 16
1 Psychiatric Genetics: A Primer......Page 18
2 Principles of Genetic Counseling......Page 42
3 Risk Communication: Simple Tools to Foster Understanding......Page 62
Part 2: Genetics of Specific Disorders......Page 82
4 Genetics of Childhood-Onset Psychiatric Disorders......Page 84
5 Genetics of Schizophrenia and Psychotic Disorders......Page 114
6 Genetics of Mood and Anxiety Disorders......Page 146
7 Genetics of Alzheimer's Disease......Page 192
8 Neuropsychiatric Aspects of Genetic Disorders......Page 210
Part 3: Special Topics......Page 240
9 Perinatal Psychiatry and Teratogenicity......Page 242
10 Ethical, Legal, and Social Implications of Psychiatric Genetics and Genetic Counseling......Page 270
11 The Road Ahead......Page 292
Glossary......Page 320
A......Page 322
C......Page 324
D......Page 325
F......Page 327
G......Page 328
I......Page 330
M......Page 331
N......Page 332
P......Page 333
R......Page 335
S......Page 336
T......Page 337
Z......Page 338