Proteins of Iron Metabolism presents a clear picture of the structure and function of the main proteins involved in iron metabolism. The book gives you a detailed description of the structure and function of each protein, and discusses the structure and regulation of the corresponding genes in parallel. It supplies an analysis of the differential expression and regulation of these proteins.Numerous figures offer an integrated view of iron metabolism at the level of various tissues. The book delineates the mechanisms controlling cellular iron metabolism and shows how these mechanisms adapt to the differential and peculiar iron need of different cell types. Each chapter contains extensive bibliographical information providing a wide reference to the literature. The comprehensive coverage of the advances in understanding the mechanisms controlling cellular iron metabolism, especially at the molecular level, found in this book will give you insight into the regulation of iron metabolism. Proteins of Iron Metabolism fills the need for a clearly written, comprehensive review of the latest research, putting every thing you need in one easy-to-use resource.
Author(s): Ugo Testa
Edition: 1
Publisher: CRC Press
Year: 2002
Language: English
Pages: 609
City: Boca Raton, Fla
Front Cover......Page 1
Introduction......Page 6
The Author......Page 38
Table of Contents......Page 40
1. Iron Absorption......Page 44
2. Iron and Cell Proliferation: Mechanisms and Applications in Cancer Therapy......Page 82
3. Lactoferrin......Page 114
4. Transferrin......Page 186
5. Transferrin Receptor......Page 292
6. Soluble Transferrin Receptor......Page 414
7. Alternative Iron Uptake Systems......Page 426
8. Iron-Responsive Elements and Iron Regulatory Proteins......Page 450
9. Ferritin......Page 492
Index......Page 584