From disease marker identification to accelerated drug development, this reference offers a detailed overview of current and emerging trends in the field of proteomics—focusing on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein–protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of proteomic research in the past, present, and future.
Author(s): Joanna S. Albala
Edition: 1
Publisher: Marcel Dekker
Year: 2003
Language: English
Pages: 423
Team DDU......Page 1
Foreword Sam Hanash......Page 4
Preface......Page 6
Contents......Page 10
Contributors......Page 12
1. Protein Biochips and Array-Based Proteomics......Page 16
2. Ultrasensitive Microarray-Based Ligand Assay Technology......Page 96
3. Practical Approaches to Protein Microarrays......Page 142
4. Protein Biochips: Powerful New Tools to Unravel the Complexity of Proteomics?......Page 160
5. Functionalized Surfaces for Protein Microarrays: State of the Art, Challenges, and Perspectives......Page 174
6. High-Throughput Protein Expression, Purification, and Characterization Technologies......Page 188
7. Miniaturized Protein Production for Proteomics......Page 218
8. Protein Profiling: Proteomes and Subproteomes......Page 232
9. Shotgun Proteomics and Its Applications to the Yeast Proteome......Page 248
10. Forward and Reverse Proteomics: It Takes Two (or More) to Tango......Page 270
11. Dynamic Visualization of Expressed Gene Networks......Page 292
12. High-Throughput Structural Biology and Proteomics......Page 314
13. Integration of Proteomic, Genechip, and DNA Sequence Data......Page 340
14. The Proteomics Market......Page 352
Index......Page 366
