Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.
Author(s): Edward Bittar (Eds.)
Series: Advances in Molecular and Cell Biology 34
Edition: 1
Publisher: Elsevier Science & Technology
Year: 2004
Language: English
Pages: 1-333
Content:
Foreword: a historical overview of advocacy for research in sex-based biology
Pages v-xiii
Sherry A. Marts, Sarah Keitt
Contents
Pages xv-xvii
Sex chromosomes Original Research Article
Pages 1-13
Monte E. Turner, Cathy Jenkins, Amy Milsted, Daniel L. Ely
Endocrine control of sexual differentiation: effects of the maternal–fetal environment and endocrine disrupting chemicals Original Research Article
Pages 15-37
Susan C Nagel, Frederick S vom Saal
General mechanisms of steroid receptors and receptor coregulator action Original Research Article
Pages 39-48
David G. Monroe, Thomas C. Spelsberg
Non-genomic actions of hormones Original Research Article
Pages 49-57
Richard H. Karas
Hormone receptor polymorphisms Original Research Article
Pages 59-69
Amanda M Shearman
Sex, hormones and the endothelium Original Research Article
Pages 71-84
Stephanie J. Murphy, Marguerite T. Littleton-Kearney, Louise D. McCullough, Patricia D. Hurn
Sex hormones and the vascular smooth muscle Original Research Article
Pages 85-103
Julia M. Orshal, Raouf A. Khalil
Cardiovascular membrane excitability and the influence of sex and sex steroids Original Research Article
Pages 105-114
Douglas K. Bowles, Meredith Hay
Sex-differences in electrophysiology of the heart and cardiac arrhythmias Original Research Article
Pages 115-130
Thai V. Pham, Michael R. Rosen
Sex differences in cardiac muscle and remodeling Original Research Article
Pages 131-145
Brian L. Stauffer, Leslie A. Leinwand
Reflex control of the circulation Original Research Article
Pages 147-166
Christopher T Minson
Sex differences in hypertension and renal injury Original Research Article
Pages 167-182
Jane F. Reckelhoff, Lourdes A. Fortepiani, Licy L. Yanes, Valeria E. Cucchiarelli
Influence of sex hormones on the neuromuscular junction Original Research Article
Pages 183-194
Gary C. Sieck, Carlos B. Mantilla
Sex and hormonal influences on skeletal muscle; differentiation and contractile mechanisms Original Research Article
Pages 195-208
Marybeth Brown
Sex-based differences in substrate metabolism Original Research Article
Pages 209-227
Tracy Horton, Barry Braun
Sex differences in skeletal development Original Research Article
Pages 229-245
Lorraine A Fitzpatrick
Sex differences in steroid-induced synaptic plasticity Original Research Article
Pages 247-258
Russell D. Romeo, Bruce S. McEwen
Hormones and the developing brain Original Research Article
Pages 259-279
Margaret M. McCarthy
Mechanisms of sex-based neuropathologies Original Research Article
Pages 281-294
Phyllis M. Wise, Dena B. Dubal, Shane W. Rau, Adrienne B. Cashion
Sex differences in autoimmunity Original Research Article
Pages 295-306
Thomas F. Fagan, Denise L. Faustman
Influence of hormones and sex on platelet functions Original Research Article
Pages 307-319
Muthuvel Jayachandran, Virginia M. Miller
Sex differences in wound healing Original Research Article
Pages 321-328
Gillian S Ashcroft
Subject index
Pages 329-333
