Principles of Diabetes Mellitus, Second Edition is an important update to the comprehensive textbook first published in 2002 and reissued in 2004. It is written for physicians of all specialties who, on a daily basis, deal with an illness which has reached epidemic proportions. The book is also intended for medical students and investigators of all aspects of diabetes.
The last five years have witnessed major developments in our understanding of diabetes and in therapeutic approaches to this disease. Thus, in addition to updating all chapters, the authors added eight new chapters to the second edition. Principles of Diabetes Mellitus, Second Edition covers diabetes in all of its aspects—genetics, epidemiology, pathophysiology, clinical manifestations, therapy and prevention.
Author(s): Jacek Zajac, Anil Shrestha M.D., Parini Patel M.D., Leonid Poretsky M.D. (auth.), Leonid Poretsky (eds.)
Edition: 2
Publisher: Springer US
Year: 2010
Language: English
Pages: 852
Tags: Endocrinology; Diabetes; Primary Care Medicine; Cardiology
Front Matter....Pages i-xviii
Front Matter....Pages 1-1
The Main Events in the History of Diabetes Mellitus....Pages 3-16
Front Matter....Pages 17-17
Normal Glucose Homeostasis....Pages 19-35
Endocrine Pancreas....Pages 37-55
The Role of Incretins in Insulin Secretion....Pages 57-74
Cellular Mechanisms of Insulin Action....Pages 75-87
The Role of Brain in Glucose Metabolism....Pages 89-104
Front Matter....Pages 105-105
Diagnostic Criteria and Classification of Diabetes....Pages 107-115
Epidemiology....Pages 117-127
Diabetes in Culturally Diverse Populations: From Biology to Culture....Pages 129-144
Front Matter....Pages 145-145
Genetics of Type 2 Diabetes: From Candidate Genes to Genome-Wide Association Analysis....Pages 147-163
Rodent Models of Diabetes....Pages 165-178
Front Matter....Pages 179-179
Type 1 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations....Pages 181-201
Type 2 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations....Pages 203-220
Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations, and Therapy....Pages 221-232
Diabetes in Pregnancy....Pages 233-244
Secondary Causes of Diabetes Mellitus....Pages 245-258
Syndromes of Extreme Insulin Resistance....Pages 259-277
Front Matter....Pages 279-279
Acute Hyperglycemic Syndromes: Diabetic Ketoacidosis and the Hyperosmolar State....Pages 281-295
Hypoglycemia in Diabetes Mellitus....Pages 297-312
Intake of Advanced Glycation Endproducts: Role in the Development of Diabetic Complications....Pages 313-330
Front Matter....Pages 279-279
Diabetic Retinopathy....Pages 331-346
Diabetic Nephropathy....Pages 347-355
Diabetic Neuropathy....Pages 357-370
Peripheral Vascular Disease in Diabetes....Pages 371-379
The Diabetic Foot....Pages 381-399
Male Sexual Dysfunction in Diabetes Mellitus....Pages 401-417
Gastrointestinal Manifestations of Diabetes....Pages 419-434
Dyslipidemia: Pathogenesis and Management....Pages 435-456
Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents....Pages 457-471
Front Matter....Pages 473-473
Obesity – Genetics, Pathogenesis, Therapy....Pages 475-488
Hypertension....Pages 489-498
Coronary Artery Disease and Cardiomyopathy....Pages 499-513
Polycystic Ovary Syndrome....Pages 515-530
Insulin Resistance and the Metabolic Syndrome....Pages 531-555
Diabetes and Liver Disease....Pages 557-577
The Increased Risk of Cancer in Obesity and Type 2 Diabetes: Potential Mechanisms....Pages 579-599
Diabetes and Sleep Disorders....Pages 601-615
HIV Infection and Diabetes....Pages 617-642
Front Matter....Pages 643-643
Glycemic Goals....Pages 645-658
Behavioral and Educational Approaches to Diabetes Self-Management....Pages 659-675
Front Matter....Pages 643-643
Dietary Therapy of Diabetes Mellitus....Pages 677-686
Exercise in the Therapy of Diabetes Mellitus....Pages 687-708
Therapy of Type 1 Diabetes Mellitus....Pages 709-729
Treating Type 2 Diabetes Mellitus....Pages 731-747
Prevention of Microvascular Complications of Diabetes – General Overview....Pages 749-753
Psychiatric Care of the Patient with Diabetes....Pages 755-771
Management of Diabetes and Hyperglycemia in the Hospital Setting....Pages 773-786
The Future of Diabetes Therapy....Pages 787-800
Front Matter....Pages 801-801
Prevention of Type 1 Diabetes Mellitus....Pages 803-820
Prevention of Type 2 Diabetes Mellitus....Pages 821-832
Front Matter....Pages 833-833
Resources for Patients with Diabetes....Pages 835-844
Back Matter....Pages 845-887
