Covers the field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and, more. This text features coverage of genetics and the endocrinology of sepsis.
Author(s): Kenneth L. Becker, John P. Bilezikian, W. J. Bremner, Wellington Hung, C. Ronald Kahn, D. Lynn Loriaux, Eric S. Nylén, Robert W. Rebar, Gary L. Robertson, Richard H. Snider Jr., Leonard Wartofsky
Edition: 3
Publisher: Lippincott Williams & Wilkins
Year: 2001
Language: English
Commentary: From archive.org: https://archive.org/details/principlespracti0000unse_j9k9
Pages: 2477
City: Philadelphia
Front Cover
Title Page
Copyright
Editors
Contributing Authors
Preface
Preface to the First Edition
Contents
I: General Principles of Endocrinology (Becker)
1: Endocrinology and the Endocrine Patient (Becker, Nylen, & Snider)
2: Molecular Biology: Present and Future (Hussain & Habener)
3: Biosynthesis and Secretion of Peptide Hormones (Chin)
4: Hormonal Action (Granner)
5: Feedback Control in Endocrine Systems (Darlington & Dallman)
6: Endocrine Rhythms (van Cauter)
7: Growth and Development in the Normal Infant and Child (August)
II: The Endocrine Brain and Pituitary Gland
8: Morphology of the Endocrine Brain, Hypothalamus, and Neurohypophysis (Sladek & Sladek)
9: Physiology and Pathophysiology of the Endocrine Brain and Hypothalamus (Cooper)
10: Pineal Gland (Reiter)
11: Morphology of the Pituitary in Health and Disease (Thapar, Kovacs, & Horvath)
A: Adenohypophysis
12: Growth Hormone and its Disorders (Baumann)
13: Prolactin and its Disorders (Katznelson & Klibanski)
14: Adrenocorticotropin: Physiology and Clinical Aspects (Torpy & Jackson)
15: Thyroid-Stimulating Hormone and its Disorders (Cohen)
16: Pituitary Gonadotropins and their Disorders (Bremner, Huhtaniemi, & Amory)
17: Hypopituitarism (Pinzone)
18: Hypothalamic and Pituitary Disorders in Infancy and Childhood (Rogol)
19: The Optic Chiasm in Endocrinologic Disorders (Siatkowski & Glaser)
20: Diagnostic Imaging of the Sellar Region (Bourekas, Oehler, & Chakeres)
21: Medical Treatment of Pituitary Tumors and Hypersecretory States (Sarne)
22: Radiotherapy of Pituitary-Hypothalamic Tumors (Mehta)
23: Neurosurgical Management of Pituitary-Hypothalamic Neoplasms (Baskin)
24: Pituitary Tumors: Overview of Therapeutic Options (Chanson)
B: Neurohypophysial System
25: Physiology of Vasopressin, Oxytocin, and Thirst (Robertson)
26: Diabetes Insipidus and Hyperosmolar Syndromes (Baylis & Thompson)
27: Inappropriate Antidiuresis and Other Hypoosmolar States (Verbalis)
III: The Thyroid Gland (Wartofsky)
28: Approach to the Patient with Thyroid Disease (Wartofsky)
29: Morphology of the Thyroid Gland (Livolski)
30: Thyroid Physiology: Synthesis and Release, Iodine Metabolism, Binding and Transport (Reed)
31: Thyroid Physiology: Hormone Action, Receptors, and Postreceptor Events (Yen)
32: Thyroid Hormone Resistance Syndromes (Usala)
33: Thyroid Function Tests (Smallridge)
34: Thyroid Uptake and Imaging (Sarker & Becker)
35: Thyroid Sonography, Computed Tomography, and Magnetic Resonance Imaging (Blum)
36: Abnormal Thyroid Function Test Results in Euthyroid Persons (Burch)
37: Adverse Effects of Iodide (Nuovo & Wartofsky)
38: Nontoxic Goiter (Davis & Davis)
39: The Thyroid Nodule (Wartofsky & Ahmann)
40: Thyroid Cancer (Mazzaferri)
41: Unusual Thyroid Cancers (Ringel)
42: Hyperthyroidism (Burman)
43: Endocrine Ophthalmopathy (Alper & Wartofsky)
44: Surgery of the Thyroid Gland (Kaplan)
45: Hypothyroidism (Shapiro & Surks)
46: Thyroiditis (Jackson & Hennessey)
47: Thyroid Disorders of Infancy and Childhood (Hung)
IV: Calcium and Bone Metabolism (Bilezikian)
48: Morphology of the Parathyroid Glands (Livolsi)
49: Physiology of Calcium Metabolism (Brown)
50: Physiology of Bone (Raisz)
51: Parathyroid Hormone (Goltzmann & Hendy)
52: Parathyroid Hormone-Related Protein (Strewler)
53: Calcitonin Gene Family of Peptides (Becker et al.)
54: Vitamin D (Clemens & O'Riordan)
55: Bone Quantification and Dynamics of Turnover (Dempster & Shane)
56: Markers of Bone Metabolism (Seibel, Robins, & Bilezikian)
57: Clinical Application of Bone Mineral Density Measurements (Miller, Erickson, & Zapalowski)
58: Primary Hyperparathyroidism (Silverberg & Bilezikian)
59: Nonparathyroid Hypercalcemia (Stewart)
60: Hypoparathyroidism and Other Causes of Hypocalcemia (Jan de Beur, Streeten, & Levine)
61: Renal Osteodystrophy (Martin, Gonzalez, & Slatopolsky)
62: Surgery of the Parathyroid Glands (Doherty & Wells)
63: Osteomalacia and Rickets (Bell)
64: Osteoporosis (Lindsay & Cosman)
65: Paget Disease of Bone (Siris)
66: Rare Disorders of Skeletal Formation and Homeostasis (Whyte)
67: Diseases of Abnormal Phosphate Metabolism (Drezner)
68: Magnesium Metabolism (Rude)
69: Nephrolithiasis (Favus & Coe)
70: Disorders of Calcium and Bone Metabolism in Infancy and Childhood (Carpenter)
V: The Adrenal Glands (Loriaux)
71: Morphology of the Adrenal Cortex and Medulla (O'Brien)
72: Synthesis and Metabolism of Corticosteroids (White)
73: Corticosteroid Action (White)
74: Tests of Adrenocortical Function (Loriaux)
75: Cushing Syndrome (Schteingart)
76: Adrenocortical Insufficiency (Loriaux)
77: Congenital Adrenal Hyperplasia (Speiser)
78: Corticosteroid Therapy (Axelrod)
79: Renin-Angiotensin System And Aldosterone (Corry & Tuck)
80: Hyperaldosteronism (Gill)
81: Hypoaldosteronism (Melby)
82: Endocrine Aspects of Hypertension (Corry & Tuck)
83: Adrenocortical Disorders in Infancy and Childhood (Rosenfield & Ke-Nan Qin)
84: The Incidental Adrenal Mass (Loriaux)
85: Physiology of the Adrenal Medulla and the Sympathetic Nervous System (Goldstein)
86: Pheochromocytoma and Other Diseases of the Sympathetic Nervous System (Keiser)
87: Adrenomedullary Disorders of Infancy and Childhood (Hung)
88: Diagnostic Imaging of the Adrenal Glands (Miller)
89: Surgery of the Adrenal Glands (Peplinski & Norton)
VI: Sex Determination and Development (Rebar & Bremner)
90: Normal and Abnormal Sexual Differentiation and Development (Simpson & Rebar)
91: Physiology of Puberty (Lee)
92: Precocious and Delayed Puberty (Walvoord, Waguespack, & Pescovitz)
93: Micropenis, Hypospadias, and Cryptorchidism in Infancy and Childhood (Hung)
VII: Endocrinology of the Female (Rebar)
94: Morphology and Physiology of the Ovary (Erickson & Schreiber)
95: The Normal Menstrual Cycle and the Contrl of Ovulation (Rebar, Hodgen, & Zinger)
96: Disorders of Menstruation, Ovulation, and Sexual Response (Rebar)
97: Ovulation Induction (Thomas)
98: Endometriosis (Barbieri)
99: Premenstrual Syndrome (Reid & Fretts)
100: Menopause (Walsh & Schiff)
101: Hirsutism, Alopecia, and Acne (Carmina & Lobo)
102: Functioning Tumors and Tumor-Like Conditions of the Ovary (Yeh, Zaloudek, & Kurman)
103: The Differential Diagnosis of Female Infertility (Ory & Barrionuevo)
104: Female Contraception (Goldberg & Darney)
105: Complications and Side Effects of Steroidal Contraception (Goldberg & Darney)
106: Morphology of the Normal Breast, its Hormonal Control, and Pathophysiology (Blackwell)
107: Conception, Implantation, and Early Development (Iannaccone, Walterhouse, & Pfendler)
108: The Maternal-Fetal-Placental Unit (Carr)
109: Endocrinology of Parturition (Challis)
110: Endocrine Disease of Pregnancy (Molitch)
111: Trophoblastic Tissue and its Abnormalities (Kaplan)
112: Endocrinology of Trophoblastic Tissue (Lei & Rao)
VIII: Endocrinology of the Male (Bremner)
113: Morphology and Physiology of the Testis (de Kretser)
114: Evaluation of Testicular Function (Winters)
115: Male Hypogonadism (Plymate)
116: Testicular Dysfunction in Systemic Disease (Baker)
117: Erectile Dysfunction (Cunningham & Hirshkowitz)
118: Male Infertility (Clark)
119: Clinical Use and Abuse of Androgens and Antiandrogens (Matsumoto)
120: Gynecomastia (Glass)
121: Endocrine Aspects of Benign Prostatic Hyperplasia (Miller & Ellis)
122: Testicular Tumors (Skakkebaek & Rorth)
123: Male Contraception (Amory & Bremner)
IX: Disorders of Fuel Metabolis (Kahn)
A: Food and Energy
124: Principles of Nutritional Management (Durschlag & Smith)
125: Appetite (Hirschberg)
126: Obesity (Hirsch, Salans, & Aronne)
127: Starvation (MacDonald & Smith)
128: Anorexia Nervosa and Other Eating Disorders (Warren & Locke)
129: Fuel Homeostasis and Intermediary Metabolism of Carbohydrate, Fat, and Protein (Ruderman, Tornheim, & Goodman)
130: Vitamins: Hormonal and Metabolic Interrelationships (Abou-Saif & Lipman)
131: Trace Minerals: Hormonal and Metabolic Interrelationships (Lindeman)
132: Exercise: Endocrine and Metabolic Effects (Leblanc)
B: Diabetes Mellitus
133: Morphology of the Endocrine Pancreas (Bonner-Weir)
134: Islet Cell Hormones: Production and Degradaation (Weir & Halban)
135: Glucose Homeostasis and Insulin Action (Kahn)
136: Classification, Diagnostic Tests, and Pathogenesis of Type 1 Diabetes Mellitus (Eisenbarth)
137: Etiology and Pathogenesis of Type 2 Diabetes Mellitus and Related Disorders (Kahn)
138: Natural History of Diabetes Mellitus (Krolewski & Warram)
139: Secondary Forms of Diabetes Mellitus (Catanese & Kahn)
140: Evaluation of Metabolic Control in Diabetes (Goldfine)
141: Diet and Exercise in Diabetes (Gnda)
142: Oral Agentss for the Treatment of Type 2 Diabetes Mellitus (Goldfine & Maratos-Flier)
143: Insulin Therapy and its Complications (Weir)
144: Pancreas and islet Transplantation (Weir)
145: Syndrome X (Reaven)
146: Syndromes of Extreme Insulin Resistance (Flier & Mantzoros)
147: Cardiovascular Complications of Diabetes Mellitus (Hehenberger & King)
148: Diabetic Neuropathy (Feldman et al.)
149: Gastrointestinal Complications of Diabetes (Gordon & Falchuk)
150: Diabetic Nephropathy (Defronzo)
151: Diabetes and the Eye (Rand)
152: Diabetes and Infection (Eliopoulos)
153: Diabetes and the Skin (Tanenberg & Eastman)
154: The Diabetic Foot (Gibbons)
155: Diabetic Acidosis, Hyperosmolar Coma, and Lactic Acidosis (George & Alberti)
156: Diabetes Mellitus and Pregnancy (Jovanovic)
157: Diabetes Mellitus in the Infant and Child (Becker & Drash)
C: Hypoglycemia
158: Hypoglycemic Disorders in the Adult (Comi & Gorden)
159: Localization of Islet Cell Tumors (Miller)
160: Surgery of the Endocrine Pancreas (White)
161: Hypoglycemia of Infancy and Childhood (Wolfsdorf & Korson)
D: Lipid Metabolism
162: Biochemistry and Physiology of Lipid and Lipoprotein Metabolism (Mahley)
163: Lipoprotein Disorders (Schaefer)
164: Treatment of the Hyperlipoproteinemias (Larosa)
165: Endocrine Effects on Lipids (Ginsberg, Goldberg, & Tuck)
166: Lipid Abnormalities in Diabetes Mellitus (Ratner, Howard, & Howard)
X: Diffuse Hormonal Secretion (Nylen)
167: General Characteristics of Diffuse Peptide Hormone Systems (Rehfeld)
168: Endogenous Opioid Peptides (Cox & Mueller)
169: Somatostatin (Patel)
170: Kinins (Regoli)
171: Substance P and the Tachykinins (Aronin)
172: Prostaglandins, Thromboxanes, and Leukotrienes (Robertson)
173: Growth Factors and Cytoskines (Leroith & Blakesley)
174: Compendium of Growth Factors and Cytokines (Aggarwal)
175: The Diffuse Neuroendocrine System (Nylen & Becker)
176: The Endocrine Brain (Kastin et al.)
177: The Endocrine Lung (Becker)
178: The Endocrine Heart (Rademaker & Espiner)
179: The Endocrine Endothelium (Cosentino & Lüscher)
180: The Endocrine Blood Cells (Dave & Müller)
181: The Endocrine Mast Cell (Wasserman)
182: The Endocrine Enteric System (Holst)
183: The Endocrine Kidney (Dubrow & Desimone)
184: The Endocrine Genitourinary Tract (Fahrenkrug & Gras)
185: The Endocrine Skin (Pittelkow)
186: The Endocrine Adipocyte (Ahima & Flier)
XI: Heritable Abnormalities of Endocrinology and Metabolism (Becker)
187: Inheritance Patterns of Endocrinologic and Metabolic Disorders (Schimke)
188: Multiple Endocrine Neoplasia (Sizemore)
189: Heritable Disorders of Collagen and Fibrillin (Byers)
190: Heritable Diseases of Lysosomal Storage (Cohen)
191: Heritable Diseases of Amino-Acid Metabolism (Stern & Finkelstein)
192: Heritable Diseases of Purine Metabolism (Holmes & Nashel)
XII: Immunologic Basis of Endocrine Disorders (Wartofsky)
193: The Endocrine Thymus (Goldstein & Hall)
194: Immunogenetics, the Human Leukocyte Antigen System, and Endocrine Disease (Baker)
195: T Cells in Endocrine Disease (Weetman)
196: B Cells and Autoantibodies in Endocrine DIsease (McGregor)
197: The Immune System and it Role in Endocrine Function (Volpe)
XIII: Endocrine and Metabolic Dysfunction in the Growing Child and in the Aged (Hung)
198: Short Stature and Slow Growth in the Young (Aceto et al.)
199: Endocrinology and Aging (Gruenewald & Matsumoto)
XIV: Interrelationships Between Hormones and the Body (Becker)
200: Cerebral Effects of Endocrine Disease (Leigh)
201: Psychiatric-Hormonal Interrelationships (Kling et al.)
202: Respiration and Endocrinology (Rohatgi & Becker)
203: The Cardiovascular System and Endocrine Disease (Seely & Williams)
204: Gastrointestinal Manifestations of Endocrine Disease (Halline)
205: The Liver and Endocrine Function (de Maria, Colantoni, & van Thiel)
206: Effects of Nonrenal Hormones on the Normal Kidney (Kimmel, Rivera, & Khatri)
207: Renal Metabolism of Hormones (Rabkin & Hausmann)
208: Effects of Endocrine Disease on the Kidney (Kelepouris & Agus)
209: Endocrine Dysfunction Due to Renal Disease (Mooradian)
210: Neuromuscular Manifestations of Endocrine Disease (Layzer & Abrams)
211: Rheumatic Manifestations of Endocrine Disease (Nashel)
212: Hematologic Endocrinology (Luksenburg, Goldberg, & Kessler)
213: Infectious Diseases and Endocrinology (Tuazon & Migueles)
214: Endocrine Disorders in Human Immunodeficiency Virus Infection (Migueles & Tuazon)
215: The Eye in Endocrinology (Oppenheim & Mathers)
216: Otolaryngology and Endocrine Disease (Harner)
217: Dental Aspects of Endocrinology (Redman)
218: The Skin and Endocrine Disorders (Fine, Nasir, & Becker)
XV: Hormones and Cancer (Becker)
219: Paraneoplastic Endocrine Syndromes (Becker & Silva)
220: Endocrine Tumors of the Gastrointestinal Tract (Taheri, Meeran, & Bloom)
221: Carcinoid Tumor and the Carcinoid Syndrome (Maton)
222: Hormones and Carcinogenesis: Laboratory Studies (Li & Li)
223: Sex Hormones and Carcinogenesis: Epidemiology (Hoover)
224: Endocrine Treatment of Breast Cancer (Hortobagyi)
225: Endocrine Aspects of Prostate Cancer (Moon & Logethetis)
226: Endocrine Consequences of Cancer Therapy (Bajorunas)
XVI: Endocrinology of Critical Illness (Nylen)
227: Critical Illness and Systemic Inflammation (Zaloga, Bhatt, & Marik)
228: Endocrine Markers and Mediators in Critical Illness (Alarifi et al.)
229: The Hypothalamic-Pituitary-Adrenal Axis in Stress and Critical Illness (Bornstein & Chrousos)
230: Neuroendocrine Response to Acute Versus Prolonged Critical Illness (van den Berghe)
231: Fuel Metabolism and Nutrient Delivery in Critical Illness (Ziegler)
232: Endocrine Therapeutics in Critical Illness (Nylen et al.)
XVII: Endocrine and Metabolic Effects of Toxic Agents (Becker)
233: Endocrine-Metabolic Effects of Alcohol (Noth & Swislocki)
234: Metabolic Effects of Tobacco, Cannabis, and Cocaine (Silva)
235: Environmental Factors and Toxins and Endocrine Function (Welch)
XVIII: Endocrine Drugs and Values (Becker)
236: Compendium of Endocrine-Related Drugs (Misra, Magee, & Nylen)
237: Reference Values in Endocrinology (Dufour)
238: Techniques of Laboratory Testing (Dufour)
239: Effects of Drugs on Endocrine Function and Values (Sharma)
240: DNA Diagnosis of Endocrine Disease (Hejtmancik & Ostrer)
241: Dynamic Procedures in Endocrinology (Dufour & Jubiz)
Index
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