This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. Authored by a carefully selected group of the world’s leading clinicians and scientists, the book is divided into three sections. The opening chapters cover general principles, including epidemiology, pathogenesis, tumor stem cells, supportive care, complications of therapy, and quality of life. The remaining two sections are comprised of treatment-oriented chapters covering the spectrum of gliomas and rarer tumor types. Each of these chapters presents multi-disciplinary therapeutic approaches and addresses specific disease concerns. Throughout, the authors incorporate the cutting-edge advances in molecular biology and genomics that are revolutionizing neuro-oncology. The result is an important clinical resource which provides evidence-based data and interpretation essential to intelligent therapeutic decision making.
Author(s): Christine Lu-Emerson MD, Andrew D. Norden (auth.), Andrew D. Norden, David A. Reardon, Patrick C. Y. Wen (eds.)
Series: Current Clinical Oncology
Edition: 1
Publisher: Humana Press
Year: 2011
Language: English
Pages: 570
Tags: Oncology; Neurosurgery; Neurology; Radiotherapy
Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Epidemiology and Risk Factors....Pages 3-25
Molecular Pathogenesis....Pages 27-44
Cellular Origins of Malignant Glioma: The Cancer Stem Cell Polemic....Pages 45-53
Principles of Supportive Care....Pages 55-84
Principles of Clinical Trial Design and Response Assessment....Pages 85-102
Complications of Therapy....Pages 103-141
Neuropsychological Function and Quality of Life....Pages 143-170
Front Matter....Pages 171-171
Low-Grade Gliomas....Pages 173-194
High-Grade Astrocytomas....Pages 195-232
Anaplastic Oligodendrogliomas and Mixed Gliomas....Pages 233-248
Ependymomas....Pages 249-262
Uncommon Gliomas in Adults: Brainstem Gliomas, Pilocytic Astrocytomas, and Pleomorphic Xanthoastrocytomas....Pages 263-282
Front Matter....Pages 283-283
Pediatric Tumors....Pages 285-332
Primary Central Nervous System Lymphoma....Pages 333-353
Meningiomas....Pages 355-375
Pituitary Adenomas....Pages 377-400
Vestibular Schwannomas....Pages 401-413
Medulloblastomas....Pages 415-433
Pineal Region Tumors....Pages 435-455
Genetic Syndromes....Pages 457-497
Front Matter....Pages 283-283
Rare Tumors....Pages 499-528
Spinal Tumors....Pages 529-547
Back Matter....Pages 549-568
