Assessment of skin physiology is moving rapidly away from a purely descriptive approach as we gain a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as those relating to its barrier function and hydration. As a result of research utilizing bioengineering methods, reliable and reproducible approaches are now available for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This book examines in detail all aspects of cosmetic testing – legal, general, and practical. After discussion of regulatory and ethical issues and guidelines, essential guidance is provided on the planning, performance, and evaluation of scientific studies in skin physiology. The topics addressed range from laboratory and staffing requirements through to testing devices and methods, factors influencing measurements, and study design. In addition, detailed information is provided on test settings for a range of cosmetic products. All of the authors are recognized experts in their field. This book will be invaluable to researchers, students, and medical staff in explaining how best to assess skin functions in controlled studies using non-invasive biophysical instruments.
Author(s): Oliver Wunderlich (auth.), Joachim Fluhr (eds.)
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2011
Language: English
Pages: 272
Tags: Dermatology; Allergology
Front Matter....Pages i-xi
Front Matter....Pages 1-1
Regulatory Aspects....Pages 3-13
Ethical Aspects of Cosmetic Testing....Pages 15-25
Good Clinical Practice....Pages 27-31
Guidelines in Dermocosmetic Testing....Pages 33-41
Claim Support: How to Create and Substantiate Claims....Pages 43-61
Front Matter....Pages 63-63
Testing Laboratory....Pages 65-73
Research Staff....Pages 75-77
Testing Population....Pages 79-82
Testing Devices and Methods....Pages 83-88
Factors Influencing Measurements....Pages 89-99
Study Design....Pages 101-106
Cosmetic Testing Report....Pages 107-119
Front Matter....Pages 121-121
Moisturizers and Emollients....Pages 123-141
Antiaging and Antiwrinkle Products....Pages 143-153
Products for Impure, Acne-Like Skin....Pages 155-170
Assessment of Hair Morphology....Pages 171-178
Skin Colour and Pigmentation....Pages 179-185
Characterization of Sunscreens: Determination of the SPF....Pages 187-195
Practical Aspects of Shampoo and Conditioner Testing....Pages 197-215
Antiperspirants and Deodorants....Pages 217-226
Front Matter....Pages 121-121
Hair Growth....Pages 227-245
Sensory Perception....Pages 247-252
Practical Use and Significance of Transepidermal Water Loss Measurements....Pages 253-259
Compliance Check with On-Site Measurements: Advanced Ways in Product Testing....Pages 261-265
Back Matter....Pages 267-272