Poly(ethylene glycol). Chemistry and Biological Applications

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Content: Introduction to chemistry and biological applications of poly(ethylene glycol) / Samuel Zalipsky and J. Milton Harris --
Theory of poly(ethylene glycol) in solution / Gunnar Karlström and Ola Engkvist --
The conformation of polymers at interfaces / Danilo D. Lasic --
Safety of poly(ethylene glycol) and poly(ethylene glycol) derivatives / Peter K. Working, Mary S. Newman, Judy Johnson, and Joel B. Cornacoff --
Poly(ethylene glycol)-grafted liposome therapeutics / Martin C. Woodle --
Poly(ethylene oxide)-bearing lipids and interaction of functionalized liposomes with intact cells / Y. Okumura, N. Higashi, V. Rosilio, and J. Sunamoto --
Poly(ethylene glycol)-based micelles for drug delivery / Sung Bum La, Yukio Nagasaki, and Kazunori Kataoka --
The use of poly(ethylene glycol)-enzymes in nonaqueous enzymology / P.A. Mabrouk --
Incorporation of poly(ethylene glycol)-proteins into polymers / Janice L. Panza, Keith E. LeJeune, Srikanth Venkatasubramanian, and Alan J. Russell --
Biochemistry and immunology of poly(ethylene glycol)-modified adenosine deaminase (PEG-ADA) / Michael S. Hershfield --
Conjugation of high-molecular weight poly(ethylene glycol) to cytokines : granulocyte-macrophage colony-stimulating factors as model substrates / Merry R. Sherman, L. David Williams, Mark G.P. Saifer, John A. French, Larry W. Kwak, and Joost J. Oppenheim --
Preparation and characterization of poly(ethylene glycol)ylated human growth hormone antagonist / Kenneth Olson, Richard Gehant, Venkat Mukku, Kathy O'Connell, Brandon Tomlinson, Klara Totpal, and Marjorie Winkler --
New synthetic polymers for enzyme and liposome modification / Francesco M. Veronese, Paolo Caliceti, and Oddone Schiavon --
Covalent and noncovalent adducts of proteins with water-soluble poly(alkylene oxides) / Irina N. Topchieva --
Isolation of positional isomers of mono-poly(ethylene glycol)ylated interferon/[alpha]-2a and the determination of their biochemical and biological characteristics / Seth P. Monkarsh, Cheryl Spence, Jill E. Porter, Alicia Palleroni, Carlo Nalin, Perry Rosen, and Pascal Bailon --
Site-specific poly(ethylene glycol)ylation of peptides / Arthur M. Felix --
Poly(ethylene glycol)-containing supports for solid-phase synthesis of peptides and combinatorial organic libraries / George Barany, Fernando Albericio, Steven A. Kates, and Maria Kempe --
Oligonucleotide-poly(ethylene glycol) conjugates : synthesis, properties, and applications / Andres Jäschke --
Design of antitumor agent-terminated poly(ethylene glycol) conjugate as macromolecular prodrug / Tatsuro Ouchi, Hidetoshi Kuroda, and Yuichi Ohya --
Poly(ethylene glycol)-grafted polymers as drug carriers / E.H. Schacht and K. Hoste --
Hydrazide derivatives of poly(ethylene glycol) and their bioconjugates / Samuel Zalipsky and Sunitha Menon-Rudolph --
Protein adsorption on poly(ethylene oxide)-grafted silicon surfaces / Susan J. Sofia and Edward W. Merrill --
Using self-assembled monolayers that present oligo(ethylene glycol) groups to control the interactions of proteins with surfaces / Milan Mrksich and George M. Whitesides --
Electrokinetic analysis of poly(ethylene glycol) coating chemistry / Kazunori Emoto, J. Milton Harris, and James M. Van Alstine --
Surface modifications with adsorbed poly(ethylene oxide)-based block coploymers : physical characteristics and biological use / Karin D. Caldwell --
In vivo stability of poly(ethylene glycol)-collagen composites / Woonza Rhee, Joel Rosenblatt, Marisol Castro, Jacqueline Schroeder, Prema R. Rao, Carol F.H. Harner, and Richard A. Berg --
Temperature-induced gelation pluronic-g-poly(acrylic acid) graft copolymers for prolonged drug delivery to the eye / Guohua Chen, Allan S. Hoffman, Bhagwati Kabra, and Kiran Randeri --
Novel degradable poly(ethylene glycol) esters for drug delivery / Xuan Zhao and Milton Harris.

Author(s): J. Milton Harris and Samuel Zalipsky (Eds.)
Series: ACS Symposium Series 680
Publisher: American Chemical Society
Year: 1997

Language: English
Pages: 490
City: Washington, DC