The seventh edition of the benchmark evidence-based pharmacotherapy text--now in full color! Includes Online Learning Center--that features 11 additional chapters, learning objectives, interactive questions, and more! A Doody's Core Title ESSENTIAL PURCHASE! 4 STAR DOODY'S REVIEW! "This book is, by far, one of the best in pharmacy. It is an exceptionally useful reference for both pharmacists and pharmacy students. It communicates a wealth of information that is well researched and referenced. The seventh edition is a much needed update."--Doody's Review Service When it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Pharmacotherapy delivers everything you need to know to provide safe, effective drug therapy across the full range of therapeutic categories. The book also delves into psychosocial issues that affect compliance--topics related to a patient's ability to understand and manage often-complex therapy--and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes. FEATURES Key Concepts in each chapter Critical Presentation boxes that summarize common disease signs and symptoms Clinical Controversies boxes that examine complicated issues you face when providing drug therapy Therapeutic recommendations in each disease-specific chapter Evaluation of Therapeutic Outcomes Information in each disease-specific chapter containing key monitoring guidelines NEW MATERIAL! including chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorous Homeostatis, and Multiple Myeloma NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine
Author(s): Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey
Edition: 7
Year: 2008
Language: English
Pages: 2592
Front Page
......Page 1
Dedication
......Page 6
Contents
......Page 8
Contributors
......Page 14
Foreword......Page 28
Foreword to the First Edition
......Page 30
Preface
......Page 32
Pharmacoeconomics: Principles, Methods, and Applications......Page 34
Health Outcomes and Quality of Life......Page 36
Evidence-Based Medicine......Page 38
Documentation of Pharmacy Services......Page 40
Clinical Pharmacokinetics and Pharmacodynamics......Page 42
Pharmacogenetics......Page 64
Pediatrics......Page 80
Geriatrics......Page 90
Pharmacoepidemiology......Page 100
Clinical Toxicology......Page 102
Emergency Preparedness: Identification and Management of Biological Exposures......Page 124
Emergency Preparedness: Identification and Managementof Chemical and Radiological Exposures......Page 126
Cardiovascular Testing......Page 128
Appendix 13-2
Types of Tests for Various Cardiac Diseases or Features......Page 154
Cardiopulmonary Arrest......Page 156
Hypertension......Page 172
Heart Failure......Page 206
Ischemic Heart Disease......Page 250
Acute Coronary Syndromes......Page 282
The Arrhythmias......Page 312
Diastolic Heart Failure and the Cardiomyopathies......Page 348
Venous Thromboembolism......Page 364
Stroke......Page 406
Hyperlipidemia......Page 418
Peripheral Arterial Disease......Page 442
Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock......Page 450
Hypovolemic Shock......Page 474
Introduction to Pulmonary Function Testing......Page 488
Asthma......Page 496
Chronic Obstructive Pulmonary Disease......Page 528
Pulmonary Hypertension......Page 552
Drug-Induced Pulmonary Diseases......Page 554
Cystic Fibrosis......Page 568
Evaluation of the Gastrointestinal Tract......Page 580
Gastroesophageal Reflux Disease......Page 588
Peptic Ulcer Disease......Page 602
Inflammatory Bowel Disease......Page 622
Nausea and Vomiting......Page 640
Diarrhea, Constipation, and Irritable Bowel Syndrome......Page 650
Portal Hypertension and Cirrhosis......Page 666
Drug-Induced Liver Disease......Page 684
Pancreatitis......Page 692
Viral Hepatitis......Page 708
Drug Therapy Individualization in Patients with Hepatic Disease or Genetic Alterations in Drug Metabolizing Activity......Page 726
Quantification of Renal Function......Page 738
Acute Renal Failure......Page 756
Chronic Kidney Disease: Progression-Modifying Therapies......Page 778
Chronic Kidney Disease: Management of Complications......Page 798
Hemodialysis and Peritoneal Dialysis......Page 826
Drug-Induced Kidney Disease......Page 828
Glomerulonephritis......Page 844
Drug Therapy Individualization for Patients with Renal Insufficiency......Page 866
Disorders of Sodium and Water Homeostasis......Page 878
Disorders of Calcium and Phosphorus Homeostasis......Page 894
Disorders of Potassium and Magnesium Homeostasis......Page 910
Acid–Base Disorders......Page 922
Evaluation of Neurologic Illness......Page 942
Multiple Sclerosis......Page 946
Epilepsy......Page 960
Status Epilepticus......Page 986
Acute Management of the Brain Injury Patient......Page 998
Parkinson’s Disease......Page 1010
Pain Management......Page 1022
Headache Disorders......Page 1038
Evaluation of Psychiatric Illness......Page 1054
Childhood Disorders......Page 1062
Eating Disorders......Page 1074
Alzheimer’s Disease......Page 1084
Substance-Related Disorders: Overview and Depressants, Stimulants, and Hallucinogens......Page 1100
Substance-Related Disorders: Alcohol, Nicotine, and Caffeine......Page 1116
Schizophrenia......Page 1132
Depressive Disorders......Page 1156
Bipolar Disorder......Page 1174
Anxiety Disorders I: Generalized Anxiety, Panic, and Social Anxiety Disorders......Page 1194
Anxiety Disorders II: Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder......Page 1212
Sleep Disorders......Page 1224
Developmental Disabilities......Page 1236
Diabetes Mellitus......Page 1238
Thyroid Disorders......Page 1276
Adrenal Gland Disorders......Page 1298
Pituitary Gland Disorders......Page 1314
Pregnancy and Lactation: Therapeutic Considerations......Page 1330
Contraception......Page 1346
Menstruation-Related Disorders......Page 1362
Endometriosis......Page 1378
Hormone Therapy in Women......Page 1384
Erectile Dysfunction......Page 1402
Management of Benign Prostatic Hyperplasia......Page 1420
Urinary Incontinence......Page 1432
Function and Evaluation of the Immune System......Page 1450
Systemic Lupus Erythematosus and Other Collagen-Vascular Diseases......Page 1464
Allergic and Pseudoallergic Drug Reactions......Page 1480
Solid-Organ Transplantation......Page 1492
Osteoporosis and Other Metabolic Bone Diseases......Page 1516
Rheumatoid Arthritis......Page 1538
Osteoarthritis......Page 1552
Gout and Hyperuricemia......Page 1572
Glaucoma......Page 1584
Allergic Rhinitis......Page 1598
Dermatologic Drug Reactions and Self-Treatable Skin Disorders......Page 1610
Acne Vulgaris......Page 1624
Psoriasis......Page 1636
Atopic Dermatitis......Page 1652
Hematopoiesis......Page 1660
Anemias......Page 1672
Coagulation Disorders......Page 1698
Sickle Cell Disease......Page 1718
Drug-Induced Hematologic Disorders......Page 1734
Laboratory Tests to Direct Antimicrobial Pharmacotherapy......Page 1748
Antimicrobial RegimenSelection......Page 1764
Appendix 109-1 Drugs of Choice, First Choice, Alternative(s)......Page 1773
Central Nervous SystemInfections......Page 1776
Lower RespiratoryTract Infections......Page 1794
Upper RespiratoryTract Infections......Page 1812
Influenza......Page 1824
Skin and Soft-Tissue Infections......Page 1834
Infective Endocarditis......Page 1854
Tuberculosis......Page 1872
Gastrointestinal Infections and Enterotoxigenic Poisonings......Page 1890
Intraabdominal Infections......Page 1908
Parasitic Diseases......Page 1920
Appendix 119-1 Antiparasitic Drugs......Page 1931
Urinary Tract Infections and Prostatitis......Page 1932
Sexually Transmitted Diseases......Page 1948
Bone and Joint Infections......Page 1966
Sepsis and Septic Shock......Page 1976
Superficial Fungal Infections......Page 1990
Invasive Fungal Infections......Page 2006
Infections in Immunocompromised Patients......Page 2036
Antimicrobial Prophylaxis in Surgery......Page 2060
Vaccines, Toxoids, and Other Immunobiologics......Page 2074
Appendix 128-1 2007 Childhood and Adolescent Immunization Schedules......Page 2092
Appendix 128-2 2007 Adult Immunization Schedule......Page 2095
Human Immunodeficiency Virus Infection......Page 2098
Cancer Treatment and Chemotherapy......Page 2118
Breast Cancer......Page 2154
Lung Cancer......Page 2190
Colorectal Cancer......Page 2208
Prostate Cancer......Page 2240
Lymphomas......Page 2252
Ovarian Cancer......Page 2278
Acute Leukemias......Page 2292
Chronic Leukemias......Page 2314
Multiple Myeloma......Page 2328
Myelodysplastic Syndromes......Page 2342
Skin Cancer......Page 2344
Hematopoietic Stem Cell Transplantation......Page 2364
Assessment of Nutrition Status and Nutrition Requirements......Page 2382
Prevalence and Significance of Malnutrition......Page 2400
Parenteral Nutrition......Page 2412
Enteral Nutrition......Page 2432
Nutritional Considerations in Major Organ Failure......Page 2450
Obesity......Page 2470
GLOSSARY......Page 2488
INDEX......Page 2514
Appendix......Page 2594
