Obesity is one of the most relevant public health concerns today and it is now evident that body weight control is achieved through highly integrated physiological interactions like nutrient selection as well as being influenced by genetic and environmental factors. Moreover, energy balance regulation is a complex process aimed at maintaining constant energy stores. Presenting a detailed and comprehensive account of the roles of specific peptides in energy balance, food intake control and co-morbidities, this review provides a better understanding of the patho-physiology of energy balance and obesity.
Author(s): Gema Fruhbeck
Edition: First
Publisher: CABI
Year: 2009
Language: English
Pages: 411
Contents......Page 6
Contributors......Page 8
Preface......Page 12
1. Orexigenic Peptides......Page 14
2. Anorexigenic Peptides......Page 46
3. Newcomers and Supporting Actors......Page 74
4. The Gut as a Second Brain......Page 106
5. Elements of the Adipostat......Page 128
6. Natriuretic Peptides and Other Lipolytic Peptides Involved in the Control of Lipid Mobilization in Humans......Page 146
7. The Adipo–Hepato–Insular Axis in Glucose Homeostasis......Page 176
8. Adipokines in the Immune–Stress Response......Page 208
9. Peptides Involved in Vascular Homeostasis......Page 242
10. Hierarchy of Neural Pathways Controlling Energy Homeostasis......Page 276
11. Energy Regulatory Signals and Food Reward......Page 298
12. Embracing Complexity: The Emergence of Functional Neuroimaging and Other Methodologies to Study the Role of the Human Brain in the Pathophysiology of Obesity......Page 322
13. Overview of the Integrative Physiology of Adipose Tissue in Energy Homeostasis......Page 344
14. Application of 'Omic' Strategies to Obesity Research......Page 362
15. Implications for the Future of Obesity Management......Page 382
A......Page 404
C......Page 405
G......Page 406
H......Page 407
I......Page 408
O......Page 409
U......Page 410
Z......Page 411
