Pathophysiology, Pharmacology, and Biochemistry of Dyskinesia

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.

  • Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Author(s): Jonathan Brotchie, Erwan Bezard and Peter Jenner (Eds.)
Series: International Review of Neurobiology 98
Edition: 1
Publisher: Academic Press
Year: 2011

Language: English
Pages: 1-641

Content:
International Review of Neurobiology
Pages i-iii

Copyright
Page iv

Contributors
Pages xiii-xvi

Preface
Pages xvii-xviii

An Introduction to Dyskinesia—The Clinical Spectrum
Pages 1-29
Ainhi D. Ha, Joseph Jankovic

l-Dopa-Induced Dyskinesia—Clinical Presentation, Genetics, and Treatment
Pages 31-54
L.K. Prashanth, Susan Fox, Wassilios G. Meissner

Experimental Models of l-DOPA-Induced Dyskinesia
Pages 55-93
Tom H. Johnston, Emma L. Lane

Molecular Mechanisms of l-DOPA-Induced Dyskinesia
Pages 95-122
Gilberto Fisone, Erwan Bezard

New Approaches to Therapy
Pages 123-150
Jonathan Brotchie, Peter Jenner

Surgical Approach to l-Dopa-Induced Dyskinesias
Pages 151-171
Tejas Sankar, Andres M. Lozano

Clinical and Experimental Experiences of Graft-Induced Dyskinesia
Pages 173-186
Emma L. Lane

Tardive Dyskinesia: Clinical Presentation and Treatment
Pages 187-210
Peter N. van Harten, Diederik E. Tenback

Epidemiology and Risk Factors for (Tardive) Dyskinesia
Pages 211-230
Diederik E. Tenback, Peter N. van Harten

Genetics of Tardive Dyskinesia
Pages 231-264
Heon-Jeong Lee, Seung-Gul Kang

Animal Models of Tardive Dyskinesia
Pages 265-287
Shrinivas Krishnarao Kulkarni, Ashish Dhir

Surgery for Tardive Dyskinesia
Pages 289-296
Stéphane Thobois, Alice Poisson, Philippe Damier

Huntington's Disease: Clinical Presentation and Treatment
Pages 297-323
Marianne J.U. Novak, Sarah J. Tabrizi

Genetics and Neuropathology of Huntington's Disease
Pages 325-372
Anton Reiner, Ioannis Dragatsis, Paula Dietrich

Pathogenic Mechanisms in Huntington's Disease
Pages 373-418
Lesley Jones, Alis Hughes

Experimental Models of HD and Reflection on Therapeutic Strategies
Pages 419-481
Jinho Kim, Olivia L. Bordiuk, Robert J. Ferrante

Cell-Based Treatments for Huntington's Disease
Pages 483-508
Stephen B. Dunnett, Anne E. Rosser

Clinical Phenomenology of Dystonia
Pages 509-524
Carlo Colosimo, Alfredo Berardelli

Genetics and Pharmacological Treatment of Dystonia
Pages 525-549
Matthew J. Barrett, Susan Bressman

Experimental Models of Dystonia
Pages 551-572
Annalisa Tassone, Giuseppe Sciamanna, Paola Bonsi, Giuseppina Martella, Antonio Pisani

Surgical Treatment of Dystonia
Pages 573-589
John Yianni, Alexander L. Green, Tipu Z. Aziz

Index
Pages 591-606

Contents of Recent Volumes
Pages 607-641