Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Pathology, Toxicogenetics, and Criminalistics of Drug Abuse presents a detailed introduction to the cutting-edge advances in this emerging field. Beginning with a definition and explanation of the scheduling of controlled substances, the book covers all illicit drugs, as well as several legitimate pharmaceutical preparations that are used illicitly, including steroids. It describes in detail the most common pathologic syndromes seen in the hearts, lungs, and central nervous systems of drug abusers and explains how inherited genetic defects and variations can alter drug effects. Written by leading investigators in the field, this useful volume describes the techniques most commonly used by forensic analysts including chemical confirmatory tests such as microcrystal identification and gas chromatography/mass spectrometry. The book reviews the basics of toxicogenetics, including the molecular changes in cardiac structure ("channelopathies") that may cause sudden death.
Author(s): MD, FFFLM, Steven B. Karch
Edition: 1
Year: 2007
Language: English
Pages: 210
Front cover......Page 1
Contents......Page 6
Preface......Page 8
The Editor......Page 10
Contributors......Page 12
CHAPTER 1. The Criminalistics of Controlled Substances......Page 14
CHAPTER 2. Overview of Pathology of Drug Abuse: Scene of Death and the Autopsy......Page 84
CHAPTER 3. Heart Disease......Page 92
CHAPTER 4. Vascular Effects of Substance Abuse*......Page 110
CHAPTER 5. Myocardial Alterations in Drug Abusers......Page 128
CHAPTER 6. Valvular Heart Disease......Page 136
CHAPTER 7. Lung Disease......Page 142
CHAPTER 8. Disorders of the Central Nervous System......Page 150
CHAPTER 9. Toxicogenetics in Drug Abuse: Pharmacogenomics for Toxicology*......Page 166
CHAPTER 10. Toxicogenetics in Drug Abuse: Heritable Channelopathies and Myopathies......Page 178
Index......Page 198
Back cover......Page 210