Pathology of the Pancreas

Pathology of the Pancreas
Series Preface
Volume Preface
Acknowledgements
Editors Biography
Series Editor Biography
Contributors
A
Acinar Cell Carcinoma
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Acinar Cell Nodules
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Acinar Cystic Transformation of the Pancreas
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Acinar-Ductal Metaplasia
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Acute Pancreatitis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Agenesis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Age-Related Changes
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Alcohol-Related Chronic Pancreatitis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Anatomic Variants
Introduction
Embryological Basis
Pancreas Divisum, Treatment
Annular Pancreas, Treatment
Heterotopic (Ectopic) Pancreatic Tissue, Treatment
Pancreatobiliary Maljunction, Treatment
Vascular Abnormalities
Henle´s Trunk
Cross-References
References and Further Reading
Anatomy of the Pancreas
Anatomy
Size, Weight
Anatomical Considerations of the Common Surgical Procedures for Resection of Pancreatic Tumors
References and Further Reading
Annular Pancreas
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Autoimmune Pancreatitis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
C
Cystic Fibrosis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Molecular Features
Differential Diagnosis
References and Further Reading
D
Ductal Adenocarcinoma and Variants
Synonyms
Definition
Clinical Features
Incidence and Etiology
Age
Sex
Site
Treatment
Outcome
Macroscopy
Microscopy
Cytology
Immunophenotype
Molecular Features
Differential Diagnosis
Histological Subtypes
Adenosquamous and Squamous Cell Carcinoma
Colloid Carcinoma
Hepatoid Carcinoma
Medullary Carcinoma
Invasive Micropapillary Carcinoma
Signet-Ring Cell (Poorly Cohesive Cell) Carcinoma
Undifferentiated Carcinoma
Undifferentiated Carcinoma with Osteoclast-Like Giant Cells
Other Neoplasms
Cross-References
References and Further Reading
E
Ectopic Tissue
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Embryogenesis and Organogenesis of the Pancreas
Embryogenesis of the Pancreas
Organogenesis of the Pancreas
Lineage Differentiation
References and Further Reading
F
Familial and Inherited Pancreatic Cancer
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Foregut Cyst
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
G
Glucagon Cell Hyperplasia and Neoplasia
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Grossing of Distal Pancreatectomy Specimens, Surgical Pathology
Synonyms
Definition
Principle
Methodology
Quality Aspects
Applications
Table with Examples (Links)
References and Further Reading
Grossing of Pancreatoduodenectomy Specimens, Surgical Pathology
Synonyms
Definition
Principle
Methodology
Quality Aspects
Applications
Table with Examples (Links)
References and Further Reading
H
Haemochromatosis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Molecular Features
Differential Diagnosis
References and Further Reading
Hereditary Chronic Pancreatitis
Definition
Clinical Features
Macroscopy
Microscopy
Molecular Features
Differential Diagnosis
References and Further Reading
Histology of the Pancreas
Anatomy and Macroscopy
Function
Size
Microscopy
References and Further Reading
I
Intraductal Oncocytic Papillary Neoplasm of the Pancreas (IOPN) and IOPN with Associated Invasive Component
Synonyms
Definition
Clinical Features
Outcome
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN with Associated Invasive Component
Synonyms
Definition
Clinical Features
Symptoms and Signs
Macroscopy
Microscopy
Gastric-type IPMN
Intestinal-type IPMN
Pancreatobiliary IPMN
IPMN with Associated Invasive Component
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Intraductal Tubulopapillary Neoplasm (ITPN) and ITPN with Associated Invasive Component
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Islet Cell Changes
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
L
Laparoscopic and Robot-Assisted Pancreatic Resections
Introduction
Pancreatoduodenectomy
Distal Pancreatectomy
Enucleation
Conclusion
References and Further Reading
Lobulocentric Atrophy
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
Cross-References
References and Further Reading
Clinical Features
Lymphoepithelial Cyst
Definition
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
M
Mixed Neuroendocrine-Non-neuroendocrine Neoplasms of the Pancreas (MiNENs)
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
Molecular Pathology of Acinar Cell Carcinoma
Description
Cross-References
References and Further Reading
Molecular Pathology of Acinar Cystic Transformation
Synonyms
Description
References and Further Reading
Molecular Pathology of Intraductal Papillary Mucinous Neoplasms
Description
Cross-References
References and Further Reading
Molecular Pathology of Mucinous Cystic Neoplasms
Synonyms
Description
References and Further Reading
Molecular Pathology of Neuroendocrine Carcinoma
Synonyms
Description
Cross-References
References and Further Reading
Molecular Pathology of Neuroendocrine Tumors
Synonyms
Description
References and Further Reading
Molecular Pathology of Pancreatic Ductal Adenocarcinoma
Synonyms
Description
Cross-References
References and Further Reading
Molecular Pathology of Pancreatic Intraepithelial Neoplasms
Synonyms
Description
Cross-References
References and Further Reading
Molecular Pathology of Serous Cystic Neoplasms
Synonyms
Description
References and Further Reading
Molecular Pathology of Solid Pseudopapillary Neoplasms
Synonyms
Description
References and Further Reading
Molecular Subtypes of Pancreatic Ductal Adenocarcinoma
Synonyms
Description
References and Further Reading
Mucinous Cystic Neoplasm (MCN) and MCN with Associated Invasive Component
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
Multiple Endocrine Neoplasia 1 Syndrome
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Molecular Features
Differential Diagnosis
References and Further Reading
N
Neuroendocrine Carcinoma of the Pancreas
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Neuroendocrine Neoplasm of the Pancreas (PanNEN)
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Neuroendocrine Tumors of the Pancreas, Well-Differentiated (PanNET Grade 1,2,3)
Synonyms
Definition
Clinical Classification of PanNET
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Non-epithelial Neoplasms
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
P
Pancreas Divisum
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pancreatic Heterotopia
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pancreatic Intraepithelial Neoplasia (PanIN)
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pancreatitis, Rare Forms
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pancreatobiliary Maljunction
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pancreatoblastoma
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
Parasitic Cyst
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Pathology Reporting, Surgical Pathology
Synonyms
Definition
Principle
Methodology
Quality Aspects
Applications
Table with Examples (Links)
References and Further Reading
Pseudocyst
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
R
Retention Cyst
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References
S
Secondary Neoplasms of the Pancreas
Synonyms
Definition
Clinical Features
Treatment
Outcome
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Serous (Cystic) Neoplasms of the Pancreas
Synonyms
Definition
Variants
Macroscopy
Microscopy
Immunohistochemical and Molecular Phenotype
Differential Diagnosis
Treatment and Outcome
References and Further Reading
Serous Cystic Neoplasms of the Pancreas, VHL-Associated
Synonyms
Definition
Macroscopy
Microscopy
Immunohistochemical and Molecular Phenotype
Differential Diagnosis
Treatment and Outcome
References and Further Reading
Serous Cystic Neoplasms, Macrocystic (Oligocystic) Type
Synonyms
Definition
Macroscopy
Microscopy
Immunohistochemical and Molecular Phenotype
Differential Diagnosis
Treatment and Outcome
References and Further Reading
Simple Mucinous Cyst
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Solid Pseudopapillary Neoplasm (SPN)
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
T
Tropical Pancreatitis
Synonyms
Definition
Clinical Features
Macroscopy
Microscopy
Immunophenotype
Molecular Features
Differential Diagnosis
References and Further Reading
Types of Pancreatic Resections
Introduction
Partial Pancreaticoduodenectomy with or Without Pylorus Preservation
Distal Pancreatectomy
Total Pancreatectomy With/Without Splenectomy
Central Pancreatectomy
Enucleation
Duodenum-Preserving Pancreatic Resections
Duodenum-Preserving Pancreatic Head Resection (Beger Procedure)
Conclusion
References and Further Reading
V
Vascular Resections in Surgery for Pancreatic Cancer
Introduction
Venous Resections
Arterial Resections
Neoadjuvant Therapy and R0 Resection
Resection Versus Palliative Chemotherapy and Palliative Surgery
Conclusion
References and Further Reading
Von Hippel-Lindau Syndrome, Pathology of the Pancreas
Definition
Clinical Features
Macroscopy
Microscopy
Molecular Features
Differential Diagnosis
References and Further Reading