This volume includes paradigms, model systems, and techniques for the study of dysfunctions in the nervous system. The advantages and disadvantages of the approaches presented are critically discussed. Key Features* Neural injury* Developmental cell death* Disease processes and aging
Author(s): J. Regino Perez-Polo (Eds.)
Series: Methods in Neurosciences 30
Edition: 1
Publisher: Elsevier, Academic Press
Year: 1996
Language: English
Pages: 1-335
Content:
Contributors
Pages vii-iix
Preface
Page xi
J. Regino Perez-Polo
Methods in neurosciences
Pages xiii-xiv
[1] Paradigms for study of neurotrophin effects in oxidant injury Original Research Article
Pages 1-25
George R. Jackson, J. Regino Perez-Polo
[2] Nitric oxide toxicity in central nervous system cultures Original Research Article
Pages 26-43
Valina L. Dawson, Ted M. Dawson
[3] Development of in Vitro injury models for oligodendroglia Original Research Article
Pages 44-54,IN1-IN2
A. Espinosa, P. Zhao, J. de Vellis
[4] Glia models to study glial cell cytotoxicity Original Research Article
Pages 55-80
Antonia Vernadakis, M. Susan Kentroti
[5] Rodent glioma models Original Research Article
Pages 81-96
William W. Maggio
[6] Peripheral lesioning of olfactory system: Expression of neurotrophin receptors Original Research Article
Pages 97-105
Christopher P. Turner, J. Regino Perez-Polo
[7] Basal forebrain cholinergic lesions and complete transection of septal-hippocampal pathway Original Research Article
Pages 106-114,IN3
Lawrence R. Williams
[8] Neurochemical lesions: Tools for functional assessment of serotonin neuronal systems Original Research Article
Pages 115-123
Joan M. Lakoski, Ashish Dugar, B. Jane Keck
[9] Cerebral glucose/energy metabolism: Valid techniques in humans and animals Original Research Article
Pages 124-134
Siegfried Hoyer
[10] Heavy metal effects on glia Original Research Article
Pages 135-166
Evelyn Tiffany-Castiglioni, Marie E. Legare, Lora A. Schneider, Rola Barhoumi, Robert C. Burghardt, Edward D. Harris, Yongchang Qian, Jan Zmudzki
[11] Source, metabolism, and function of cysteine and glutathione in the central nervous system Original Research Article
Pages 167-177
David K. Rassin
[12] Magnetic resonance spectroscopy of neural tissue Original Research Article
Pages 178-208
Richard J. McClure, Kanagasabai Panchalingam, William E. Klunk, Jay W. Pettegrew
[13] Acute stroke diagnosis with magnetic resonance imaging Original Research Article
Pages 209-242
Stephen C. Jones, Alejandro D. Perez-Trepechio, Neng C. Huang, Michael J. Quast, Gilbert R. Hillman, Thomas A. Kent
[14] Evaluation of free radical-initiated oxidant events within the nervous system Original Research Article
Pages 243-259
Stephen C. Bondy
[15] Exogenous administration of cytokines into the central nervous system: Analysis of alterations in cell morphology and molecular expression Original Research Article
Pages 260-274
M.A. Kahn, J. de Vellis
[16] Animal models to produce cortical cholinergic dysfunction Original Research Article
Pages 275-289
Reinhard Schliebs, Volker Bigl
[17] In vitro studies of liposome-mediated gene transfection Original Research Article
Pages 290-297
K. Yang, R.L. Hayes, J. Regino Perez-Polo, F. Faustinella, G. Taglialatela
[18] Construction and analysis of transgenic mice expressing amyloidogenic fragments of Alzheimer amyloid protein precursor Original Research Article
Pages 298-314
Rachael L. Neve, Frederick M. Boyce
[19] Golgi technique used to study stress and glucocorticoid effects on hippocampal neuronal morphology Original Research Article
Pages 315-325
Ana María Magariños, Bruce S. McEwen, Eberhard Fuchs, Gabriele Flügge
Index
Pages 327-335