The panniculitides are a group of heterogeneous inflammatory diseases involving the subcutaneous fat. Traditionally, the clinical and the histopathological study of the panniculitides have been considered one of the most difficult subjects in dermatology. The reasons for this relative unpopularity of the panniculitides are varied. The purpose of this issue of Dermatologic Clinics is to present a clinico-pathologic overview of some panniculitides. Emphasis will be placed on the characteristic histopathologic features for specific diagnosis, and will include short comments about the treatment for each entity.
Author(s): Luis Requena MD
Series: The Clinics: Dermatology
Edition: 1
Publisher: Saunders
Year: 2008
Language: English
Commentary: 54198
Pages: 155
Cover......Page 1
Preface......Page 2
Anatomy and Histology of Normal Subcutaneous Fat, Necrosis of Adipocytes, and Classification of the Panniculitides......Page 4
Anatomy and histology of the subcutaneous tissue......Page 5
Necrosis of the adipocytes......Page 7
References......Page 9
Etiology......Page 10
Pathogenesis......Page 13
Clinical features......Page 14
Histopathology......Page 15
References......Page 18
Clinical features of erythema induratum of Bazin......Page 24
Pathology of erythema induratum of Bazin......Page 25
Historic evolution of the concept of erythema induratum of Bazin and its relationship with nodular vasculitis......Page 26
The relation of erythema induratum of Bazin with Mycobacterium tuberculosis infection......Page 27
Diagnosis......Page 28
References......Page 29
Pathogenesis......Page 31
Histopathology......Page 32
Analytic findings......Page 33
References......Page 34
Clinical features......Page 36
Histopathologic features......Page 38
Histopathologic Differential Diagnosis......Page 42
Oral Corticosteroids......Page 43
References......Page 44
Clinical manifestations......Page 47
Histopathology......Page 49
Treatment......Page 50
References......Page 51
Histopathologic Features......Page 53
Clinical Manifestations......Page 54
Histopathologic Features......Page 55
Mycobacterium Ulcerans......Page 56
Panniculitis Caused by Mycobacterium Leprae......Page 57
Clinical Manifestations......Page 58
Histologic Features......Page 59
References......Page 60
Histopathology......Page 63
Treatment......Page 64
References......Page 65
Epidemiology......Page 66
Clinical findings......Page 67
Poststeroid Panniculitis......Page 68
Histopathology......Page 69
References......Page 70
Fat Necrosis of the Newborn......Page 71
Poststeroid Panniculitis......Page 74
Erythema Nodosum......Page 75
Panniculitis in Connective Tissue Disorders and Vasculitis......Page 76
Malignant Panniculitis......Page 77
Idiopathic lipoatrophic panniculitis in childhood......Page 78
References......Page 79
Histopathology......Page 81
References......Page 83
Histopathology......Page 85
Histopathologic differential diagnosis......Page 86
References......Page 88
Concept......Page 89
Vascular Disorders......Page 91
Connective Tissue Diseases......Page 92
Inflammatory Disorders of the Subcutaneous Tissue (Panniculitis)......Page 93
Etiopathogenic mechanisms......Page 95
References......Page 96
Etiopathogenesis......Page 98
Clinical features......Page 100
Histopathology......Page 102
References......Page 105
Subcutaneous panniculitic-like T-cell lymphoma: an evolving concept......Page 107
Clinical Features......Page 108
Histopathologic Features......Page 109
Molecular Biology Data......Page 110
Diagnosis......Page 111
Differential Diagnosis......Page 112
Treatment......Page 114
gamma/delta+ T-cell Lymphoma Involving the Subcutaneous Tissue......Page 115
Other Primary Cutaneous Lymphomas Involving the Subcutaneous Tissue......Page 116
References......Page 117
Subcutaneous Sweet syndrome......Page 119
Clinical manifestations......Page 120
Differential diagnosis......Page 121
Erythema Nodosum......Page 122
Erythema Nodosum-Like Lesions of BehCet Disease......Page 124
alpha1-Antitrypsin Deficiency Panniculitis......Page 125
Comment......Page 126
References......Page 127
Clinical features......Page 130
Relation to systemic sarcoidosis......Page 131
Histopathology......Page 132
References......Page 133
Calciphylaxis: A Changing Concept......Page 134
Cutaneous Vascular Calcification as an Epiphenomenon......Page 135
Pathogenesis......Page 136
Systemic Manifestations......Page 137
Histopathologic Features......Page 138
Calcium/Phosphate Metabolism Control......Page 140
References......Page 141
Congenital Generalized Lipodystrophy (Berardinelli-Seipp Syndrome)......Page 146
Familial Partial Lipodystrophy......Page 147
Acquired Generalized Lipodystrophy (Lawrence Syndrome)......Page 148
HIV-Associated Lipodystrophy......Page 149
Diagnosis of facial lipoatrophy......Page 151
Therapy for lipodystrophies......Page 152
References......Page 153
