Project "Keeping the Science Current".American Institute for Cancer Research / World Cancer Research Fund USA, 2012. —37 p.World Cancer Research Fund / American Institute for Cancer Research. Continuous Update
Project Report. Food, Nutrition, Physical Activity, and the Prevention of Pancreatic Cancer. 2012.
Available at http://www.dietandcancerreport.org.This report provides an updated version of section 7.6 Pancreas from the Second Expert Report:
Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective. This section
has been updated based on Panel discussions in June 2012 on the Continuous Update Project
Pancreatic Cancer Systematic Literature review (SLR), prepared by the research team at Imperial
College London, UK in 2011 (see acknowledgements). The SLR included research papers
published until September 2011. For further details please see the full 2011 Continuous Update
Project Pancreatic Cancer SLR (www.dietandcancerreport.org).To keep the evidence current and updated into the future, WCRF/AICR is undertaking the
Continuous Update Project (CUP), in collaboration with Imperial College London. The project is an ongoing review of food, nutrition, physical activity and body fatness and cancer research. The CUP builds upon the foundations of the WCRF/AICR Second Expert Report (SER) [1].
The Continuous Update Project provides a comprehensive and up to date depiction of scientific
developments on the relationship between food, nutrition, physical activity, body fatness and
cancer. It also provides an impartial analysis and interpretation of the data as a basis for
reviewing and where necessary revising WCRF/AICR's Recommendations for Cancer Prevention
based on the Second Expert Report [1].In the same way that the Second Expert Report was informed by a process of SLRs, the
Continuous Update Project systematically reviews the science. The updates to the SLRs are being conducted by a team of scientists at Imperial College London in liaison with the original SLR centres. WCRF/AICR has convened a panel of experts (the Continuous Update Project Panel (see acknowledgements)) consisting of leading scientists in the field of food, nutrition, physical activity, body fatness and cancer, who consider the updated evidence from systematic literature reviews and draw conclusions.Once all the cancers have been updated in the CUP database in 2015, the Panel will formally
review the WCRF/AICR Recommendations for Cancer Prevention, and any changes will be
communicated through the WCRF global network science, education and communications
programmes in 2017. From 2015 the CUP database will be continuously updated with new
evidence for each cancer. Prior to 2017 the Panel will revise one or more Recommendations only
if they agree there is strong evidence for a change.Instead of periodically repeating the extensive task of conducting multiple systematic literature
reviews that cover a long period of time, the continuous review process is based on a live system of scientific data. The database is updated on an ongoing basis from which, at any point in time, the most current review of scientific data (including meta-analyses where appropriate) can be performed.Periodically WCRF/AICR will produce updated SLRs, peer reviewed by scientists, which will outline
the scientific developments in the field of food, nutrition, physical activity, body weight and
cancer.Trends, incidence, and survival
Pathogenesis
Other established causes
Interpretation of the evidence
General
Specific
Methodology
Mechanistic evidence
Evidence and judgements
Red meat
Processed meat
Foods
containing total fat and saturated fatty acids
Coffee
Alcoholic drinks
Foods and beverages containing fructose
Body fatness
Greater childhood growth
Other
Comparison with the Second Expert Report
Conclusions
Acknowledgements
References
