Author(s): Samir A. Farghaly
Year: 2012
Language: English
Pages: 416
City: Rijeka
Cover......Page 1
Ovarian Cancer – Basic Science Perspective......Page 2
©......Page 3
Contents......Page 5
Preface......Page 8
1 Epidemiology and Etiology of Ovarian Cancer......Page 11
2 Inflammation and Ovarian Cancer......Page 27
3 Photonic Sensor System for Screening Serum Biomarker Proteins in Ovarian Cancer......Page 61
4 The Role of MUC16 Mucin (CA125) in the Pathogenesis of Ovarian Cancer......Page 77
5 Apoptosis Pathways in Ovarian Cancer......Page 95
6 Oncogenic Pathway Signatures and Survival Outcome......Page 115
7 Dysregulated TGFB Signaling in Ovarian Cancer......Page 131
8 New Tumor Biomarkers in Ovarian Cancer and Its Prognostic and Clinical Relevance......Page 149
9 Sensitive Detection of Epithelial Ovarian Cancer Biomarkers Using Tag-Laser Induced Breakdown Spectroscopy......Page 163
10 Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis......Page 181
11 Transcriptomic Analysis of Human Ovarian Cancer Cells: Changes Mediated by Luteinizing Hormone Receptor Activation......Page 207
12 Potential Tumor Biomarkers for Ovarian Cancer......Page 223
13 Ectoenzymes in Epithelial Ovarian Carcinoma: Potential Diagnostic Markers and Therapeutic Targets......Page 255
14 P53 Network in Ovarian Cancer......Page 281
15 Gene Amplification in Ovarian Carcinomas: Lessons from Selected Amplified Gene Families......Page 297
16 Nitric Oxide/Protein Kinase G-Iα Promotes c-Src Activation, Proliferation and Chemoresistance in Ovarian Cancer......Page 325
17 VEGF Targeting Agents in Ovarian Cancer......Page 345
18 Autotaxin – A Target for the Treatment of Drug-Resistant Ovarian Cancer?......Page 365
19 Potential Monoclonal Antibody Therapy for the Treatment of Ovarian Cancer......Page 395