A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).
Author(s): Dallas C. Jones, Marc N. Wein, Laurie H. Glimcher (auth.), Yongwon Choi (eds.)
Series: Advances in Experimental Medicine and Biology 602
Edition: 1
Publisher: Springer US
Year: 2007
Language: English
Pages: 156
Tags: Immunology; Microbiology; Infectious Diseases; Biotechnology; Pathology; Pharmacology/Toxicology
Front Matter....Pages i-xvi
Schnurri-3: A Key Regulator of Postnatal Skeletal Remodeling....Pages 1-13
Ectodomain Shedding of Receptor Activator of NF-κB Ligand....Pages 15-21
The Negative Role of IDS in Osteoclastogenesis....Pages 23-31
Functional Genetic and Genomic Analysis of Modeled Arthritis....Pages 33-42
Dexamethsone Suppresses Bone Formation via the Osteoclast....Pages 43-46
Immunologic Regulation of Bone Development....Pages 47-56
PTH Regulates the Hematopoietic Stem Cell Niche in Bone....Pages 57-60
Regulation of Hematopoietic Stem Cells in the Osteoblastic Niche....Pages 61-67
The Chemokine CXCL12 and Regulation of Hsc and B Lymphocyte Development in the Bone Marrow Niche....Pages 69-75
Osteoclast Precursor Cells....Pages 77-82
Interaction with Estrogen Receptors as Treatment of Arthritis and Osteoporosis....Pages 83-92
Novel Signaling Pathways and Therapeutic Targets in Osteoclasts....Pages 93-96
The Enigmatic Function of TREM-2 in Osteoclastogenesis....Pages 97-105
Role of Cell-matrix Interactions in Osteoclast Differentiation....Pages 107-111
Positive and Negative Roles of IL-6, STAT3, and SOCS3 in Inflammatory Arthritis....Pages 113-124
Control of Osteoclast Activity and Bone Loss by IKK Subunits: New Targets for Therapy....Pages 125-134
Targeting Osteoporosis and Rheumatoid Arthritis by Active Vaccination Against RANKL....Pages 135-142
RANKL Inhibition: From Mice to Men (and Women)....Pages 143-150
Back Matter....Pages 151-156
