Oral and Maxillofacial Pathology

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Author(s): Brad W. Neville, DDS, Douglas D. Damm, DDS, Carl M. Allen, DDS, MSD, Angela C. Chi, DMD
Edition: 4
Publisher: Elsevier
Year: 2015

Language: English
Pages: 928

Oral and Maxillofacial Pathology
Copyright page
Dedication
Contributors
Preface
1 Developmental Defects of the Oral and Maxillofacial Region
◆ Orofacial Clefts
Clinical and Radiographic Features
Treatment and Prognosis
◆ Commissural Lip Pits
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Paramedian Lip Pits (Congenital Fistulas of the Lower Lip; Congenital Lip Pits)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Double Lip
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Fordyce Granules
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Leukoedema
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Microglossia (Hypoglossia)
Clinical Features
Treatment and Prognosis
◆ Macroglossia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Ankyloglossia (Tongue-Tie)
Clinical Features
Treatment and Prognosis
◆ Lingual Thyroid
Clinical Features
Treatment and Prognosis
◆ Fissured Tongue (Scrotal Tongue)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hairy Tongue (Black Hairy Tongue; Coated Tongue)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Varicosities (Varices)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Caliber-Persistent Artery
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lateral Soft Palate Fistulas
Clinical Features
Treatment and Prognosis
◆ Coronoid Hyperplasia
Clinical and Radiographic Features
Treatment and Prognosis
◆ Condylar Hyperplasia
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Condylar Hypoplasia
Clinical and Radiographic Features
Treatment and Prognosis
◆ Bifid Condyle
Clinical and Radiographic Features
Treatment and Prognosis
◆ Exostoses
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Torus Palatinus
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Torus Mandibularis
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Eagle Syndrome (Stylohyoid Syndrome; Carotid Artery Syndrome; Stylalgia)
Clinical and Radiographic Features
Treatment and Prognosis
◆ Stafne Defect (Stafne Bone Cyst; Lingual Mandibular Salivary Gland Depression; Latent Bone Cyst; Static Bone Cyst; Static Bone Defect; Lingual Cortical Mandibular Defect)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Developmental Cysts
◆ Palatal Cysts of the Newborn (Epstein’s Pearls; Bohn’s Nodules)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Nasolabial Cyst (Nasoalveolar Cyst; Klestadt Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ “Globulomaxillary Cyst”
◆ Nasopalatine Duct Cyst (Incisive Canal Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Median Palatal (Palatine) Cyst
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ “Median Mandibular Cyst”
◆ Follicular Cysts of the Skin
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Dermoid Cyst (Dysontogenic Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Thyroglossal Duct Cyst (Thyroglossal Tract Cyst)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Branchial Cleft Cyst (Cervical Lymphoepithelial Cyst)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Lymphoepithelial Cyst
Clinical Features
Histopathologic Features
Treatment and Prognosis
Other Rare Developmental Anomalies
◆ Hemihyperplasia (Hemihypertrophy)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Progressive Hemifacial Atrophy (Progressive Facial Hemiatrophy; Romberg Syndrome; Parry-Romberg Syndrome)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Segmental Odontomaxillary Dysplasia (Hemimaxillofacial Dysplasia)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Crouzon Syndrome (Craniofacial Dysostosis)
Clinical and Radiographic Features
Treatment and Prognosis
◆ Apert Syndrome (Acrocephalosyndactyly)
Clinical and Radiographic Features
Treatment and Prognosis
◆ Mandibulofacial Dysostosis (Treacher Collins Syndrome; Franceschetti-Zwahlen-Klein Syndrome)
Clinical and Radiographic Features
Treatment and Prognosis
Bibliography
Orofacial Clefts
Commissural Lip Pits
Paramedian Lip Pits
Double Lip
Fordyce Granules
Leukoedema
Microglossia
Macroglossia
Ankyloglossia
Lingual Thyroid
Fissured Tongue
Hairy Tongue
Varicosities
Caliber-Persistent Artery
Lateral Soft Palate Fistulas
Coronoid Hyperplasia
Condylar Hyperplasia
Condylar Hypoplasia
Bifid Condyle
Exostoses
Torus Palatinus and Torus Mandibularis
Eagle Syndrome
Stafne Defect
Palatal Cysts of the Newborn
Nasolabial Cyst
“Globulomaxillary Cyst”
Nasopalatine Duct Cyst
Median Palatal Cyst
“Median Mandibular Cyst”
Epidermoid Cyst
Dermoid Cyst
Thyroglossal Duct Cyst
Branchial Cleft Cyst
Oral Lymphoepithelial Cyst
Hemihyperplasia
Progressive Hemifacial Atrophy
Segmental Odontomaxillary Dysplasia
Crouzon Syndrome
Apert Syndrome
Mandibulofacial Dysostosis
2 Abnormalities of Teeth
Environmental Alterations of Teeth
◆ Environmental Effects on Tooth Structure Development
Clinical and Radiographic Features
Turner Hypoplasia
Molar-Incisor Hypomineralization
Hypoplasia Caused by Antineoplastic Therapy
Dental Fluorosis
Syphilitic Hypoplasia
Treatment and Prognosis
◆ Postdevelopmental Loss of Tooth Structure
Tooth Wear
Clinical Features
Attrition
Abrasion
Erosion
Abfraction
Treatment and Prognosis
Internal and External Resorption
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Environmental Discoloration of Teeth
Clinical Features
Extrinsic Stains
Intrinsic Stains
Treatment and Prognosis
◆ Localized Disturbances in Eruption
Delayed Eruption
Clinical and Radiographic Features
Treatment and Prognosis
Impaction
Clinical and Radiographic Features
Treatment and Prognosis
Ankylosis
Clinical and Radiographic Features
Treatment and Prognosis
Developmental Alterations of Teeth
◆ Developmental Alterations in the Number of Teeth
Clinical Features
Hypodontia
Hyperdontia
Treatment and Prognosis
◆ Developmental Alterations in the Size of Teeth
Clinical Features
Microdontia
Macrodontia
Treatment and Prognosis
◆ Developmental Alterations in the Shape of Teeth
Gemination, Fusion, and Concrescence
Clinical Features
Gemination and Fusion
Concrescence
Treatment and Prognosis
Accessory Cusps
Clinical and Radiographic Features
Cusp of Carabelli
Talon Cusp
Dens Evaginatus
Treatment and Prognosis
Dens Invaginatus (Dens in Dente)
Clinical and Radiographic Features
Treatment and Prognosis
Ectopic Enamel
Clinical and Radiographic Features
Enamel Pearls
Cervical Enamel Extensions
Treatment and Prognosis
Taurodontism
Clinical and Radiographic Features
Treatment and Prognosis
Hypercementosis
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Dilaceration
Clinical and Radiographic Features
Treatment and Prognosis
Supernumerary Roots
Clinical and Radiographic Features
Treatment and Prognosis
Globodontia
Clinical and Radiographic Features
Treatment and Prognosis
Lobodontia
Clinical and Radiographic Features
Treatment and Prognosis
◆ Developmental Alterations in the Structure of Teeth
Amelogenesis Imperfecta
Clinical and Radiographic Features
Hypoplastic Amelogenesis Imperfecta
Hypomaturation and Hypocalcification Variants of Amelogenesis Imperfecta (Hypomineralization Amelogenesis Imperfecta)
Amelogenesis Imperfecta with Taurodontism (Hypomaturation/Hypoplastic Amelogenesis Imperfecta)
Histopathologic Features
Treatment and Prognosis
Hereditary Disorders of Dentin
Dentin Sialophosphoprotein–Associated Dentin Defects
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Dentin Dysplasia Type I
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Regional Odontodysplasia (Ghost Teeth)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Bibliography
General References
Environmental Effects on Tooth Structure Development
Postdevelopmental Loss of Tooth Structure
Discoloration of Teeth
Localized Disturbances in Eruption
Developmental Alterations in Number of Teeth
Developmental Alterations in Size of Teeth
Gemination, Fusion, Concrescence
Accessory Cusps
Dens Invaginatus
Ectopic Enamel
Taurodontism
Hypercementosis
Dilaceration
Supernumerary Roots
Globodontia
Lobodontia
Amelogenesis Imperfecta
Dentinogenesis Imperfecta
Dentin Dysplasia Type I
Regional Odontodysplasia
3 Pulpal and Periapical Disease
◆ Pulpitis
Clinical Features
Clinically Normal Pulp
Reversible Pulpitis
Irreversible Pulpitis
Pulpal Necrosis
Chronic Hyperplastic Pulpitis
Histopathologic Features
Treatment and Prognosis
◆ Secondary and Tertiary Dentin
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Pulpal Calcifications
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Periapical Granuloma (Chronic Apical Periodontitis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Periapical Cyst (Radicular Cyst; Apical Periodontal Cyst)
Clinical and Radiographic Features
Periapical Cyst
Lateral Radicular Cyst
Residual Periapical Cyst
Histopathologic Features
Treatment and Prognosis
◆ Periapical Abscess
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Cellulitis
Clinical Features
Ludwig Angina
Cavernous Sinus Thrombosis
Treatment and Prognosis
Ludwig Angina
Cavernous Sinus Thrombosis
◆ Osteomyelitis
Clinical and Radiographic Features
Acute Suppurative Osteomyelitis
Chronic Suppurative Osteomyelitis
Histopathologic Features
Acute Suppurative Osteomyelitis
Chronic Suppurative Osteomyelitis
Treatment and Prognosis
Acute Suppurative Osteomyelitis
Chronic Suppurative Osteomyelitis
◆ Diffuse Sclerosing Osteomyelitis
Clinical and Radiographic Features
Diffuse Sclerosing Osteomyelitis
Primary Chronic Osteomyelitis
CRMO and SAPHO Syndrome
Chronic Tendoperiostitis
Histopathologic Features
Diffuse Sclerosing Osteomyelitis
Primary Chronic Osteomyelitis, CRMO, and SAPHO Syndrome
Chronic Tendoperiostitis
Treatment and Prognosis
Diffuse Sclerosing Osteomyelitis
Primary Chronic Osteomyelitis, CRMO, and SAPHO Syndrome
Chronic Tendoperiostitis
◆ Condensing Osteitis (Focal Sclerosing Osteomyelitis)
Clinical and Radiographic Features
Treatment and Prognosis
◆ Osteomyelitis with Proliferative Periostitis (Periostitis Ossificans)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Alveolar Osteitis (Dry Socket; Fibrinolytic Alveolitis)
Clinical Features
Treatment and Prognosis
Bibliography
General References
Pulpitis
Secondary and Tertiary Dentin
Pulpal Calcifications
Periapical Inflammatory Disease (Granuloma; Cyst; Abscess)
Cellulitis
Osteomyelitis
Diffuse Sclerosing Osteomyelitis
Condensing Osteitis
Osteomyelitis with Proliferative Periostitis
Alveolar Osteitis
4 Periodontal Diseases
◆ Gingivitis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Localized Juvenile Spongiotic Gingival Hyperplasia (Localized Juvenile Spongiotic Gingivitis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Necrotizing Ulcerative Gingivitis (Vincent Infection; Trench Mouth)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Plasma Cell Gingivitis (Atypical Gingivostomatitis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Granulomatous Gingivitis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Desquamative Gingivitis
◆ Drug-Related Gingival Hyperplasia (Drug-Related Gingival Overgrowth)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Gingival Fibromatosis (Fibromatosis Gingivae; Elephantiasis Gingivae)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Periodontitis
Clinical and Radiographic Features
Chronic Periodontitis
Necrotizing Ulcerative Periodontitis
Periodontal Abscess
Pericoronitis
Histopathologic Features
Treatment and Prognosis
Periodontitis
Necrotizing Ulcerative Periodontitis
Periodontal Abscess
Pericoronitis
◆ Aggressive Periodontitis
Clinical and Radiographic Features
Localized Aggressive Periodontitis
Generalized Aggressive Periodontitis
Histopathologic Features
Treatment and Prognosis
◆ Papillon-Lefèvre Syndrome
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Gingivitis
Localized Juvenile Spongiotic Gingival Hyperplasia
Necrotizing Ulcerative Gingivitis
Plasma Cell Gingivitis
Granulomatous Gingivitis
Desquamative Gingivitis
Drug-Related Gingival Hyperplasia
Gingival Fibromatosis
Periodontitis
Aggressive Periodontitis
Papillon-Lefèvre Syndrome
5 Bacterial Infections
◆ Impetigo
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Erysipelas
Clinical Features
Treatment and Prognosis
◆ Streptococcal Tonsillitis and Pharyngitis
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Scarlet Fever (Scarlatina)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Tonsillar Concretions and Tonsillolithiasis
Clinical and Radiographic Features
Diagnosis
Treatment and Prognosis
◆ Diphtheria
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Syphilis (Lues)
Clinical Features
Primary Syphilis
Secondary Syphilis
Tertiary Syphilis
Congenital Syphilis
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Gonorrhea
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Tuberculosis
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Leprosy (Hansen Disease)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Noma (Cancrum Oris; Orofacial Gangrene; Gangrenous Stomatitis; Necrotizing Stomatitis)
Clinical Features
Treatment and Prognosis
◆ Actinomycosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
Cat-Scratch Disease
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Sinusitis
Clinical and Radiographic Features
Treatment and Prognosis
Bibliography
Streptococcal Infections (Impetigo, Erysipelas, Streptococcal Pharyngitis and Tonsillitis, and Scarlet Fever)
Tonsillar Concretions and Tonsillolithiasis
Diphtheria
Syphilis
Gonorrhea
Tuberculosis
Leprosy
Noma
Actinomycosis
Cat-Scratch Disease
Sinusitis
6 Fungal and Protozoal Diseases
◆ Candidiasis
Clinical Features
Pseudomembranous Candidiasis
Erythematous Candidiasis
Chronic Hyperplastic Candidiasis (Candidal Leukoplakia)
Mucocutaneous Candidiasis
Histopathologic Features
Diagnosis
Treatment and Prognosis
Polyene Agents
Nystatin
Amphotericin B
Imidazole Agents
Clotrimazole
Ketoconazole
Triazoles
Fluconazole
Itraconazole
Posaconazole
Echinocandins
Other Antifungal Agents
Iodoquinol
◆ Histoplasmosis
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Blastomycosis
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Paracoccidioidomycosis (South American Blastomycosis)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Coccidioidomycosis (San Joaquin Valley Fever; Valley Fever; Cocci)
Clinical Features
Histopathologic Features
Diagnosis
Treatment
◆ Cryptococcosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Mucormycosis (Zygomycosis; Phycomycosis)
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Aspergillosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Toxoplasmosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Leishmaniasis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
Bibliography
Candidiasis
Histoplasmosis
Blastomycosis
Paracoccidioidomycosis
Coccidioidomycosis
Cryptococcosis
Mucormycosis
Aspergillosis
Toxoplasmosis
Leishmaniasis
7 Viral Infections
◆ Human Herpesviruses
◆ Herpes Simplex Virus
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Varicella (Chickenpox)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Herpes Zoster (Shingles)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Infectious Mononucleosis (Mono; Glandular Fever; “Kissing Disease”)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Cytomegalovirus
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Enteroviruses
Clinical Features
Herpangina
Hand-Foot-And-Mouth Disease
Acute Lymphonodular Pharyngitis
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Measles (Rubeola)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Rubella (German Measles)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Mumps (Epidemic Parotitis)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
Clinical Features
Oral and Maxillofacial Lesions Strongly Associated with HIV Infection
Candidiasis
Oral Hairy Leukoplakia
Kaposi Sarcoma
Persistent Generalized Lymphadenopathy
Non-Hodgkin Lymphoma
HIV-Associated Periodontal Disease
Less Common Oral and Maxillofacial Manifestations of HIV Infection
Mycobacterial Infection
Hyperpigmentation
HIV-Associated Salivary Gland Disease
Thrombocytopenia
Herpes Simplex Virus
Varicella-Zoster Virus
Human Papillomavirus
Other Oral and Maxillofacial Lesions Seen in HIV Infection
Histoplasmosis
Aphthous Ulcerations
Molluscum Contagiosum
Oral Squamous Cell Carcinoma
Diagnosis
Treatment and Prognosis
Bibliography
Human Herpesviruses
Herpes Simplex Virus
Varicella-Zoster Virus
Infectious Mononucleosis
Cytomegalovirus
Enteroviruses
Rubeola
Rubella
Mumps
Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
8 Physical and Chemical Injuries
◆ Linea Alba
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Morsicatio Mucosae Oris (Chronic Mucosal Chewing)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Traumatic Ulcerations
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Electrical and Thermal Burns
Clinical Features
Treatment and Prognosis
◆ Chemical Injuries of the Oral Mucosa
Aspirin
Hydrogen Peroxide
Silver Nitrate
Phenol
Endodontic Materials
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Noninfectious Oral Complications of Antineoplastic Therapy
Clinical Features
Hemorrhage
Mucositis
Dermatitis
Xerostomia
Loss of Taste
Osteoradionecrosis
Trismus
Developmental Abnormalities
Treatment and Prognosis
Mucositis
Xerostomia
Loss of Taste
Osteoradionecrosis
◆ Medication-Related Osteonecrosis of the Jaw (Bisphosphonate-Related Osteonecrosis; Antiresorptive-Related Osteonecrosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Orofacial Complications of Drug Abuse
Clinical Features
Treatment and Prognosis
◆ Anesthetic Necrosis
Clinical Features
Treatment and Prognosis
◆ Exfoliative Cheilitis
Clinical Features
Treatment and Prognosis
◆ Submucosal Hemorrhage
Clinical Features
Treatment and Prognosis
◆ Oral Trauma From Sexual Practices
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Amalgam Tattoo and Other Localized Exogenous Pigmentations
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Piercings and Other Body Modifications
Clinical and Radiographic Features
Treatment and Prognosis
◆ Oral Lesions Associated with Cosmetic Fillers
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Systemic Metallic Intoxication
Lead
Mercury
Silver
Bismuth and Arsenic
Gold
Clinical Features
Lead
Mercury
Silver
Bismuth
Arsenic
Gold
Treatment and Prognosis
◆ Smoker’s Melanosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Drug-Related Discolorations of the Oral Mucosa
Clinical Features
Treatment and Prognosis
◆ Reactive Osseous and Chondromatous Metaplasia (Cutright Lesion)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Ulceration with Bone Sequestration (Spontaneous Sequestration; Traumatic Sequestration)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Antral Pseudocysts
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ True Cysts of the Sinuses (Sinus Mucocele; Surgical Ciliated Cyst; Traumatic Ciliated Cyst; Postoperative Maxillary Cyst; Retention Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Cervicofacial Emphysema
Clinical and Radiographic Features
Treatment and Prognosis
◆ Myospherulosis
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Linea Alba
Morsicatio Buccarum
Eosinophilic Ulcerations
Electrical Burns
Oral Adverse Reactions to Chemicals
Noninfectious Complications of Antineoplastic Therapy
Medication-Related Osteonecrosis of the Jaw
Orofacial Complications of Drug Abuse
Anesthetic Necrosis
Exfoliative Cheilitis
Submucosal Hemorrhage
Oral Trauma from Sexual Practices
Localized Exogenous Pigmentations
Oral Piercings and Forked Tongue
Oral Lesions Associated with Cosmetic Fillers
Systemic Metal Intoxication
Smoker’s Melanosis
Drug-Related Discolorations of the Oral Mucosa
Reactive Osseous and Chondromatous Metaplasia
Oral Ulceration with Bone Sequestration
Pseudocysts and True Cysts of the Maxillary Sinus
Cervicofacial Emphysema
Myospherulosis
9 Allergies and Immunologic Diseases
◆ Transient Lingual Papillitis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Recurrent Aphthous Stomatitis (Recurrent Aphthous Ulcerations; Canker Sores)
Clinical Features
Minor Aphthous Ulcerations
Major Aphthous Ulcerations
Herpetiform Aphthous Ulcerations
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Behçet Syndrome (Behçet Disease; Adamantiades Syndrome)
Clinical Features
Diagnosis
Histopathologic Features
Treatment and Prognosis
◆ Sarcoidosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Orofacial Granulomatosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Wegener Granulomatosis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Mucosal Reactions to Systemic Drug Administration
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Allergic Contact Stomatitis (Stomatitis Venenata)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Perioral Dermatitis (Periorificial Dermatitis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Contact Stomatitis From Artificial Cinnamon Flavoring
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Lichenoid Contact Reaction From Dental Restorative Materials
Clinical Features
Diagnosis
Histopathologic Features
Treatment and Prognosis
◆ Angioedema (Angioneurotic Edema; Quincke Disease)
Clinical Features
Diagnosis
Treatment and Prognosis
Bibliography
Transient Lingual Papillitis
Recurrent Aphthous Stomatitis
Behçet Syndrome
Sarcoidosis
Orofacial Granulomatosis
Wegener Granulomatosis
Allergic Mucosal Reactions to Systemic Drug Administration
Allergic Contact Stomatitis
Perioral Dermatitis
Cinnamon-Induced Contact Stomatitis
Lichenoid Contact Reactions from Dental Restorative Materials
Angioedema
10 Epithelial Pathology
◆ Benign Epithelial Lesions Associated with Human Papillomavirus
Squamous Papilloma
Clinical Features
Histopathologic Features
Treatment and Prognosis
Verruca Vulgaris (Common Wart)
Clinical Features
Histopathologic Features
Treatment and Prognosis
Condyloma Acuminatum (Venereal Wart)
Clinical Features
Histopathologic Features
Treatment and Prognosis
Multifocal Epithelial Hyperplasia (Heck Disease; Multifocal Papilloma Virus Epithelial Hyperplasia; Focal Epithelial Hyperplasia)
Clinical Features
Histopathologic Features
Treatment and Prognosis
Sinonasal Papillomas
Fungiform (Septal; Squamous; Exophytic) Papilloma
Clinical Features
Histopathologic Features
Treatment and Prognosis
Inverted Papilloma (Inverted Schneiderian Papilloma; Endophytic Papilloma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Cylindrical Cell Papilloma (Oncocytic Schneiderian Papilloma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Molluscum Contagiosum
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Verruciform Xanthoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Seborrheic Keratosis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Sebaceous Hyperplasia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Ephelis (Freckle)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Actinic Lentigo (Lentigo Solaris; Solar Lentigo; Age Spot; Liver Spot; Senile Lentigo)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lentigo Simplex
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Melasma (Mask of Pregnancy; Chloasma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Melanotic Macule (Focal Melanosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Melanoacanthoma (Melanoacanthosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Acquired Melanocytic Nevus (Nevocellular Nevus; Mole)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Melanocytic Nevus Variants
Congenital Melanocytic Nevus
Clinical Features
Histopathologic Features
Treatment and Prognosis
Halo Nevus (Sutton Nevus; Leukoderma Acquisitum Centrifugum)
Clinical Features
Histopathologic Features
Treatment and Prognosis
Spitz Nevus (Benign Juvenile Melanoma; Spindle and Epithelioid Cell Nevus)
Clinical Features
Histopathologic Features
Treatment and Prognosis
Blue Nevus (Dermal Melanocytoma; Jadassohn-Tièche Nevus)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Leukoplakia (Leukokeratosis; Erythroleukoplakia)
Incidence and Prevalence
Cause
Tobacco
Alcohol
Sanguinaria
Ultraviolet Radiation
Microorganisms
Trauma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Erythroplakia (Erythroplasia; Erythroplasia of Queyrat)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Smokeless Tobacco Use and Smokeless Tobacco Keratosis (Snuff Pouch; Snuff Dipper’s Lesion; Tobacco Pouch Keratosis; Spit Tobacco Keratosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Submucous Fibrosis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Nicotine Stomatitis (Nicotine Palatinus; Smoker’s Palate)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Actinic Keratosis (Solar Keratosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Actinic Cheilosis (Actinic Cheilitis; Solar Cheilosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Keratoacanthoma (“Self-Healing” Carcinoma; Pseudocarcinoma; Keratocarcinoma; Squamous Cell Carcinoma, Keratoacanthoma Type)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Squamous Cell Carcinoma
Etiology of Oral Cancer
Tobacco Smoking
Smokeless Tobacco
Betel Quid (Paan)
Alcohol
Occupational Exposures and Environmental Pollutants
Radiation
Vitamin/Mineral Deficiencies and Dietary Factors
Bacteria
Candida
Oncogenic Viruses
Immunosuppression
Oncogenes and Tumor Suppressor Genes
Clinical and Radiographic Features
Lip Vermilion Carcinoma
Intraoral Carcinoma
Oropharyngeal Carcinoma
Metastasis
Staging
Histopathologic Features
Treatment and Prognosis
Multiple Carcinomas
◆ Verrucous Carcinoma (Snuff Dipper’s Cancer; Ackerman’s Tumor)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Spindle Cell Carcinoma (Sarcomatoid Squamous Cell Carcinoma; Polypoid Squamous Cell Carcinoma; Carcinosarcoma; Pseudosarcoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Adenosquamous Carcinoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Basaloid Squamous Carcinoma (Basaloid Squamous Cell Carcinoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Carcinoma of the Maxillary Sinus
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Sinonasal Undifferentiated Carcinoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Nasopharyngeal Carcinoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Basal Cell Carcinoma (Basal Cell Epithelioma; Rodent Ulcer)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Merkel Cell Carcinoma (Merkel Cell Tumor; Neuroendocrine Carcinoma of Skin; Small Cell Carcinoma of Skin; Trabecular Carcinoma of Skin)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Melanoma (Malignant Melanoma; Melanocarcinoma)
Clinical Features
Superficial Spreading Melanoma
Nodular Melanoma
Lentigo Maligna Melanoma
Acral Lentiginous Melanoma (Mucosal Lentiginous Melanoma)
Histopathologic Features
Treatment and Prognosis
Bibliography
Benign Epithelial Lesions Associated with Human Papillomavirus
Squamous Papilloma
Verruca Vulgaris
Condyloma Acuminatum
Multifocal Epithelial Hyperplasia
Sinonasal Papillomas
Molluscum Contagiosum
Verruciform Xanthoma
Seborrheic Keratosis
Sebaceous Hyperplasia
Ephelis
Actinic Lentigo
Lentigo Simplex
Melasma
Oral Melanotic Macule
Oral Melanoacanthoma
Melanocytic Nevus
Leukoplakia
Erythroplakia
Smokeless Tobacco Keratosis
Oral Submucous Fibrosis
Nicotine Stomatitis
Actinic Keratosis
Actinic Cheilosis
Keratoacanthoma
Squamous Cell Carcinoma
Verrucous Carcinoma
Spindle Cell Carcinoma
Adenosquamous Carcinoma
Basaloid Squamous Carcinoma
Carcinoma of the Maxillary Sinus
Sinonasal Undifferentiated Carcinoma
Nasopharyngeal Carcinoma
Basal Cell Carcinoma
Merkel Cell Carcinoma
Melanoma
11 Salivary Gland Pathology
◆ Salivary Gland Aplasia
Clinical and Radiographic Features
Treatment and Prognosis
◆ Mucocele (Mucus Extravasation Phenomenon; Mucus Escape Reaction)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Ranula
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Salivary Duct Cyst (Mucus Retention Cyst; Mucus Duct Cyst; Sialocyst)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Sialolithiasis (Salivary Calculi; Salivary Stones)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Sialadenitis
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Cheilitis Glandularis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Sialorrhea
Clinical Features
Treatment and Prognosis
◆ Xerostomia
Clinical Features
Treatment and Prognosis
◆ IgG4-Related Disease
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Sjögren Syndrome
Clinical and Radiographic Features
Laboratory Values
Histopathologic Features
Treatment and Prognosis
◆ Sialadenosis (Sialosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Adenomatoid Hyperplasia of the Minor Salivary Glands
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Necrotizing Sialometaplasia
Clinical Features
Histopathologic Features
Treatment and Prognosis
Salivary Gland Tumors
◆ General Considerations
◆ Pleomorphic Adenoma (Benign Mixed Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Oncocytoma (Oxyphilic Adenoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Oncocytosis (Multinodular Oncocytic Hyperplasia)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Warthin Tumor (Papillary Cystadenoma Lymphomatosum)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Monomorphic Adenoma
◆ Canalicular Adenoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Basal Cell Adenoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Ductal Papillomas (Sialadenoma Papilliferum; Intraductal Papilloma; Inverted Ductal Papilloma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Mucoepidermoid Carcinoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Intraosseous Mucoepidermoid Carcinoma (Central Mucoepidermoid Carcinoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Acinic Cell Carcinoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Mammary Analogue Secretory Carcinoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Malignant Mixed Tumors (Carcinoma Ex Pleomorphic Adenoma; Carcinoma Ex Mixed Tumor; Carcinosarcoma; Metastasizing Mixed Tumor)
Clinical Features
Carcinoma Ex Pleomorphic Adenoma
Carcinosarcoma
Metastasizing Mixed Tumor
Histopathologic Features
Carcinoma Ex Pleomorphic Adenoma
Carcinosarcoma
Metastasizing Mixed Tumor
Treatment and Prognosis
Carcinoma Ex Pleomorphic Adenoma
Carcinosarcoma
Metastasizing Mixed Tumor
◆ Adenoid Cystic Carcinoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Polymorphous Low-Grade Adenocarcinoma (Lobular Carcinoma; Terminal Duct Carcinoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Salivary Adenocarcinoma, Not Otherwise Specified
Clinical and Histopathologic Features
Treatment and Prognosis
Bibliography
Salivary Gland Aplasia
Mucocele
Ranula
Salivary Duct Cyst
Sialolithiasis
Sialadenitis
Cheilitis Glandularis
Sialorrhea
Xerostomia
IgG4-Related Disease
Sjögren Syndrome
Sialadenosis
Adenomatoid Hyperplasia
Necrotizing Sialometaplasia
Salivary Gland Tumors: General Considerations
Pleomorphic Adenoma
Oncocytoma and Oncocytosis
Warthin Tumor
Canalicular Adenoma
Basal Cell Adenoma
Salivary Papillomas
Mucoepidermoid Carcinoma
Intraosseous Mucoepidermoid Carcinoma
Acinic Cell Carcinoma
Mammary Analogue Secretory Carcinoma
Malignant Mixed Tumors
Adenoid Cystic Carcinoma
Polymorphous Low-Grade Adenocarcinoma
Salivary Adenocarcinoma, Not Otherwise Specified
12 Soft Tissue Tumors
◆ Fibroma (Irritation Fibroma; Traumatic Fibroma; Focal Fibrous Hyperplasia; Fibrous Nodule)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Giant Cell Fibroma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Epulis Fissuratum (Inflammatory Fibrous Hyperplasia; Denture Injury Tumor; Denture Epulis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Inflammatory Papillary Hyperplasia (Denture Papillomatosis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Fibrous Histiocytoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Solitary Fibrous Tumor (Hemangiopericytoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Fibromatosis
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Myofibroma (Myofibromatosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Oral Focal Mucinosis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Pyogenic Granuloma (Lobular Capillary Hemangioma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Peripheral Giant Cell Granuloma (Giant Cell Epulis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Peripheral Ossifying Fibroma (Ossifying Fibroid Epulis; Peripheral Fibroma with Calcification; Calcifying Fibroblastic Granuloma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lipoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Traumatic Neuroma (Amputation Neuroma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Palisaded Encapsulated Neuroma (Solitary Circumscribed Neuroma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Schwannoma (Neurilemoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Neurofibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Neurofibromatosis Type I (von Recklinghausen Disease of the Skin)
Clinical and Radiographic Features
Treatment and Prognosis
◆ Multiple Endocrine Neoplasia Type 2B
Clinical Features
Laboratory Values
Histopathologic Features
Treatment and Prognosis
◆ Melanotic Neuroectodermal Tumor of Infancy
Clinical and Radiographic Features
Laboratory Values
Histopathologic Features
Treatment and Prognosis
◆ Paraganglioma (Carotid Body Tumor; Chemodectoma; Glomus Jugulare Tumor; Glomus Tympanicum Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Granular Cell Tumor
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Congenital Epulis (Congenital Epulis of the Newborn; Congenital Granular Cell Lesion)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hemangioma and Vascular Malformations
Clinical and Radiographic Features
Hemangioma of Infancy
Vascular Malformations
Intrabony Vascular Malformations
Histopathologic Features
Treatment and Prognosis
◆ Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis; Sturge-Weber Angiomatosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Nasopharyngeal Angiofibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Lymphatic Malformations (Lymphangioma; Cystic Hygroma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Leiomyoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Rhabdomyoma
Clinical Features
Adult Rhabdomyomas
Fetal Rhabdomyomas
Histopathologic Features
Adult Rhabdomyomas
Fetal Rhabdomyomas
Treatment and Prognosis
◆ Osseous and Cartilaginous Choristomas
Clinical Features
Histopathologic Features
Treatment and Prognosis
Soft Tissue Sarcomas
◆ Fibrosarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Undifferentiated Pleomorphic Sarcoma (Malignant Fibrous Histiocytoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Liposarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Malignant Peripheral Nerve Sheath Tumor (Malignant Schwannoma; Neurofibrosarcoma; Neurogenic Sarcoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Olfactory Neuroblastoma (Esthesioneuroblastoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Angiosarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Kaposi Sarcoma
Clinical Features
Classic Type
Endemic Type
Iatrogenic Type
Histopathologic Features
Treatment and Prognosis
◆ Leiomyosarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Rhabdomyosarcoma
Clinical Features
Histopathologic Features
Embryonal Type
Alveolar Type
Treatment and Prognosis
◆ Synovial Sarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Alveolar Soft-Part Sarcoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Metastases to the Oral Soft Tissues
Clinical Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Fibroma and Giant Cell Fibroma
Epulis Fissuratum
Inflammatory Papillary Hyperplasia
Fibrous Histiocytoma
Fibromatosis
Myofibroma (Myofibromatosis)
Solitary Fibrous Tumor
Oral Focal Mucinosis
Pyogenic Granuloma
Peripheral Giant Cell Granuloma
Peripheral Ossifying Fibroma
Lipoma
Traumatic Neuroma
Palisaded Encapsulated Neuroma
Schwannoma and Neurofibroma
Neurofibromatosis Type I
Multiple Endocrine Neoplasia Type 2B
Melanotic Neuroectodermal Tumor of Infancy
Paraganglioma
Granular Cell Tumor
Congenital Epulis
Hemangioma and Vascular Malformations
Sturge-Weber Syndrome
Nasopharyngeal Angiofibroma
Lymphatic Malformations
Leiomyoma
Rhabdomyoma
Osseous and Cartilaginous Choristomas
Soft Tissue Sarcomas
Fibrosarcoma
Undifferentiated Pleomorphic Sarcoma
Liposarcoma
Malignant Peripheral Nerve Sheath Tumor
Olfactory Neuroblastoma
Angiosarcoma
Kaposi Sarcoma
Leiomyosarcoma
Rhabdomyosarcoma
Synovial Sarcoma
Alveolar Soft-Part Sarcoma
Metastases to the Oral Soft Tissues
13 Hematologic Disorders
◆ Lymphoid Hyperplasia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hemophilia
Clinical Features
Treatment and Prognosis
◆ Plasminogen Deficiency (Ligneous Conjunctivitis; Hypoplasminogenemia)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Anemia
Clinical Features
Treatment and Prognosis
◆ Sickle Cell Anemia
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Thalassemia
Clinical and Radiographic Features
β-Thalassemia
α-Thalassemia
Treatment and Prognosis
◆ Aplastic Anemia
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Neutropenia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Agranulocytosis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Cyclic Neutropenia (Cyclic Hematopoiesis)
Clinical and Radiographic Features
Diagnosis
Histopathologic Features
Treatment and Prognosis
◆ Thrombocytopenia
Reduced Platelet Production
Increased Platelet Destruction
Sequestration in the Spleen
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Polycythemia Vera (Primary Polycythemia; Polycythemia Rubra Vera; Primary Acquired Erythrocytosis)
Clinical Features
Treatment and Prognosis
◆ Leukemia
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Langerhans Cell Histiocytosis (Histiocytosis X; Langerhans Cell Disease; Idiopathic Histiocytosis; Eosinophilic Granuloma; Langerhans Cell Granuloma; Langerhans Cell Granulomatosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Hodgkin Lymphoma (Hodgkin Disease)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Non-Hodgkin Lymphoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Mycosis Fungoides (Cutaneous T-Cell Lymphoma)
Clinical Features
Histopathologic Features
Eczematous Stage
Plaque Stage
Tumor Stage
Treatment and Prognosis
◆ Burkitt Lymphoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Extranodal NK/T-Cell Lymphoma, Nasal-Type (Angiocentric T-Cell Lymphoma; Midline Lethal Granuloma; Idiopathic Midline Destructive Disease; Polymorphic Reticulosis; Midline Malignant Reticulosis; Angiocentric Immunoproliferative Lesion)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Multiple Myeloma
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Plasmacytoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Lymphoid Hyperplasia
Hemophilia
Plasminogen Deficiency
Anemia
Sickle Cell Anemia
Thalassemia
Aplastic Anemia
Neutropenia
Agranulocytosis
Cyclic Neutropenia
Thrombocytopenia
Polycythemia Vera
Leukemia
Langerhans Cell Histiocytosis
Hodgkin Lymphoma
Non-Hodgkin Lymphoma
Mycosis Fungoides
Burkitt Lymphoma
Extranodal NK/T-Cell Lymphoma, Nasal Type
Multiple Myeloma
Plasmacytoma
14 Bone Pathology
◆ Osteogenesis Imperfecta (“Brittle Bone Disease”)
Clinical and Radiographic Features
Diagnosis
Treatment and Prognosis
◆ Osteopetrosis (Albers-Schönberg Disease; Marble Bone Disease)
Clinical and Radiographic Features
Autosomal Recessive Infantile Osteopetrosis
Autosomal Recessive Intermediate Osteopetrosis
Autosomal Dominant Adult Osteopetrosis
Histopathologic Features
Treatment and Prognosis
◆ Cleidocranial Dysplasia (Cleidocranial Dysostosis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Focal Osteoporotic Marrow Defect
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Idiopathic Osteosclerosis
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Massive Osteolysis (Gorham Disease; Gorham-Stout Syndrome; Vanishing Bone Disease; Phantom Bone Disease; Idiopathic Osteolysis)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Paget Disease of Bone (Osteitis Deformans)
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Central Giant Cell Granuloma (Giant Cell Lesion; Giant Cell Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Giant Cell Tumor (“True Giant Cell Tumor”)
◆ Cherubism
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Simple Bone Cyst (Traumatic Bone Cyst; Hemorrhagic Bone Cyst; Solitary Bone Cyst; Idiopathic Bone Cavity; Unicameral Bone Cyst)
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Aneurysmal Bone Cyst
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Fibro-Osseous Lesions of the Jaws
◆ Fibrous Dysplasia
Clinical and Radiographic Features
Monostotic Fibrous Dysplasia
Polyostotic Fibrous Dysplasia; Jaffe-Lichtenstein Syndrome; McCune-Albright Syndrome
Histopathologic Features
Treatment and Prognosis
◆ Cemento-Osseous Dysplasias (Osseous Dysplasia)
Clinical and Radiographic Features
Focal Cemento-Osseous Dysplasia
Periapical Cemento-Osseous Dysplasia (Osseous Dysplasia; Periapical Cemental Dysplasia; Periapical Cementoma)
Florid Cemento-Osseous Dysplasia
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Familial Gigantiform Cementoma
Clinical and Radiographic Findings
Histopathologic Features
Treatment and Prognosis
◆ Ossifying Fibroma (Cementifying Fibroma; Cemento-Ossifying Fibroma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Juvenile Ossifying Fibroma (Juvenile Active Ossifying Fibroma; Juvenile Aggressive Ossifying Fibroma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Osteoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Gardner Syndrome
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Osteoblastoma (Giant Osteoid Osteoma) and Osteoid Osteoma
Clinical and Radiographic Features
Osteoblastoma
Osteoid Osteoma
Histopathologic Features
Treatment and Prognosis
◆ Cementoblastoma (True Cementoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Chondroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Chondromyxoid Fibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Synovial Chondromatosis (Chondrometaplasia)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Desmoplastic Fibroma
Clinical and Radiographic Features
Histopathologic Findings
Treatment and Prognosis
◆ Osteosarcoma (Osteogenic Sarcoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Surface (Juxtacortical) Osteosarcomas
Postirradiation Bone Sarcoma
◆ Chondrosarcoma
Clinical and Radiographic Findings
Histopathologic Features
Variants
Treatment and Prognosis
Mesenchymal Chondrosarcoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Ewing Sarcoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Metastatic Tumors to the Jaws
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Osteogenesis Imperfecta
Osteopetrosis
Cleidocranial Dysplasia
Focal Osteoporotic Marrow Defect
Idiopathic Osteosclerosis
Massive Osteolysis
Paget Disease of Bone
Central Giant Cell Granuloma
Cherubism
Simple Bone Cyst
Aneurysmal Bone Cyst
Fibro-Osseous Lesions—General Aspects and Classification
Fibrous Dysplasia
Cemento-Osseous Dysplasias
Familial Gigantiform Cementoma
Ossifying Fibroma
Juvenile Ossifying Fibroma
Osteoma
Gardner Syndrome
Osteoblastoma and Osteoid Osteoma
Cementoblastoma
Chondroma
Chondromyxoid Fibroma
Synovial Chondromatosis
Desmoplastic Fibroma
Osteosarcoma
Postirradiation Bone Sarcoma
Chondrosarcoma
Ewing Sarcoma
Metastatic Tumors to the Jaws
15 Odontogenic Cysts and Tumors
Odontogenic Cysts
◆ Dentigerous Cyst (Follicular Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Eruption Cyst (Eruption Hematoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Primordial Cyst
◆ Odontogenic Keratocyst (Keratocystic Odontogenic Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Orthokeratinized Odontogenic Cyst
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Gingival (Alveolar) Cyst of the Newborn
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Gingival Cyst of the Adult
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lateral Periodontal Cyst (Botryoid Odontogenic Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Calcifying Odontogenic Cyst (Calcifying Cystic Odontogenic Tumor; Gorlin Cyst; Dentinogenic Ghost Cell Tumor; Ghost Cell Odontogenic Carcinoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Glandular Odontogenic Cyst (Sialo-Odontogenic Cyst)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Buccal Bifurcation Cyst
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Carcinoma Arising in Odontogenic Cysts
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Odontogenic Tumors
Tumors of Odontogenic Epithelium
◆ Ameloblastoma
Conventional Solid or Multicystic Intraosseous Ameloblastoma
Clinical and Radiographic Features
Histopathologic Features
Follicular Pattern
Plexiform Pattern
Acanthomatous Pattern
Granular Cell Pattern
Desmoplastic Pattern
Basal Cell Pattern
Treatment and Prognosis
Unicystic Ameloblastoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Peripheral (Extraosseous) Ameloblastoma
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Malignant Ameloblastoma and Ameloblastic Carcinoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Clear Cell Odontogenic Carcinoma (Clear Cell Odontogenic Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Adenomatoid Odontogenic Tumor
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Squamous Odontogenic Tumor
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Mixed Odontogenic Tumors
◆ Ameloblastic Fibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Ameloblastic Fibro-Odontoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Ameloblastic Fibrosarcoma (Ameloblastic Sarcoma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Odontoameloblastoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Odontoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
Tumors of Odontogenic Ectomesenchyme
◆ Central Odontogenic Fibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Peripheral Odontogenic Fibroma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Granular Cell Odontogenic Tumor (Granular Cell Odontogenic Fibroma)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Odontogenic Myxoma
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Cementoblastoma (“True Cementoma”)
Bibliography
Odontogenic Cysts and Tumors—General References and Classification
Dentigerous Cyst
Eruption Cyst
Primordial Cyst
Odontogenic Keratocyst
Orthokeratinized Odontogenic Cysts
Nevoid Basal Cell Carcinoma Syndrome
Gingival Cyst of the Newborn
Gingival Cyst of the Adult
Lateral Periodontal Cyst
Calcifying Odontogenic Cyst
Glandular Odontogenic Cyst
Buccal Bifurcation Cyst
Carcinoma Arising in Odontogenic Cysts
Ameloblastoma
Unicystic Ameloblastoma
Peripheral (Extraosseous) Ameloblastoma
Malignant Ameloblastoma and Ameloblastic Carcinoma
Clear Cell Odontogenic Tumor
Adenomatoid Odontogenic Tumor
Calcifying Epithelial Odontogenic Tumor
Squamous Odontogenic Tumor
Mixed Odontogenic Tumors
Ameloblastic Fibroma
Ameloblastic Fibro-Odontoma
Ameloblastic Fibrosarcoma
Odontoameloblastoma
Odontoma
Central Odontogenic Fibroma
Peripheral Odontogenic Fibroma
Granular Cell Odontogenic Tumor
Myxoma
16 Dermatologic Diseases
◆ Ectodermal Dysplasia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ White Sponge Nevus (Cannon Disease; Familial White Folded Dysplasia)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hereditary Benign Intraepithelial Dyskeratosis (Witkop-Von Sallmann Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Pachyonychia Congenita (Jadassohn-Lewandowsky Type; Jackson-Lawler Type)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Dyskeratosis Congenita (Cole-Engman Syndrome; Zinsser-Cole-Engman Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Xeroderma Pigmentosum
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hereditary Mucoepithelial Dysplasia
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Incontinentia Pigmenti (Bloch-Sulzberger Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Darier Disease (Keratosis Follicularis; Dyskeratosis Follicularis; Darier-White Disease)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Warty Dyskeratoma (Isolated Darier Disease; Isolated Dyskeratosis Follicularis; Focal Acantholytic Dyskeratosis; Follicular Dyskeratoma)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Peutz-Jeghers Syndrome
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Hereditary Hemorrhagic Telangiectasia (Osler-Weber- Rendu Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Ehlers-Danlos Syndromes
Clinical Features
Treatment and Prognosis
◆ Tuberous Sclerosis (Epiloia; Bourneville-Pringle Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Multiple Hamartoma Syndrome (Cowden Syndrome; PTEN Hamartoma-Tumor Syndrome)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Epidermolysis Bullosa
Clinical Features
Dominant Dystrophic Types
Recessive Dystrophic Types
Histopathologic Features
Treatment and Prognosis
Immune-Mediated Diseases and Their Evaluation
◆ Pemphigus
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Paraneoplastic Pemphigus (Neoplasia-Induced Pemphigus; Paraneoplastic Autoimmune Multiorgan Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Mucous Membrane Pemphigoid (Cicatricial Pemphigoid; Benign Mucous Membrane Pemphigoid)
Clinical Features
Histopathologic Features
Linear IgA Bullous Dermatosis
Angina Bullosa Hemorrhagica
Epidermolysis Bullosa Acquisita
Treatment and Prognosis
Topical Agents
Systemic Agents
◆ Bullous Pemphigoid
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Erythema Multiforme
Clinical Features
Erythema Multiforme Major
Histopathologic Features
Treatment and Prognosis
◆ Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Erythema Migrans (Geographic Tongue; Benign Migratory Glossitis; Wandering Rash of the Tongue; Erythema Areata Migrans; Stomatitis Areata Migrans)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Reactive Arthritis (Reiter Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lichen Planus
Clinical Features
Reticular Lichen Planus
Erosive Lichen Planus
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Chronic Ulcerative Stomatitis
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Graft-Versus-Host Disease
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Psoriasis
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Lupus Erythematosus
Clinical Features
Systemic Lupus Erythematosus
Chronic Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus Erythematosus
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Systemic Sclerosis (Progressive Systemic Sclerosis; Scleroderma; Hide-Bound Disease)
Clinical and Radiographic Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ CREST Syndrome (Acrosclerosis; Limited Scleroderma)
Clinical Features
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Acanthosis Nigricans
Clinical Features
Histopathologic Features
Treatment and Prognosis
Bibliography
Ectodermal Dysplasia
White Sponge Nevus
Hereditary Benign Intraepithelial Dyskeratosis
Pachyonychia Congenita
Dyskeratosis Congenita
Xeroderma Pigmentosum
Hereditary Mucoepithelial Dysplasia
Incontinentia Pigmenti
Darier Disease
Warty Dyskeratoma
Peutz-Jeghers Syndrome
Hereditary Hemorrhagic Telangiectasia
Ehlers-Danlos Syndromes
Tuberous Sclerosis
Multiple Hamartoma Syndrome
Epidermolysis Bullosa
Pemphigus
Paraneoplastic Pemphigus
Mucous Membrane Pemphigoid
Bullous Pemphigoid
Erythema Multiforme
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Erythema Migrans
Reactive Arthritis
Lichen Planus
Chronic Ulcerative Stomatitis
Graft-Versus-Host Disease
Psoriasis
Lupus Erythematosus
Systemic Sclerosis
CREST Syndrome
Acanthosis Nigricans
17 Oral Manifestations of Systemic Diseases
◆ Mucopolysaccharidosis
Clinical and Radiographic Features
Treatment and Prognosis
◆ Lipid Reticuloendothelioses
Clinical and Radiographic Features
Gaucher Disease
Niemann-Pick Disease
Tay-Sachs Disease
Histopathologic Features
Treatment and Prognosis
Gaucher Disease
Niemann-Pick and Tay-Sachs Disease
◆ Lipoid Proteinosis (Hyalinosis Cutis Et Mucosae; Urbach-Wiethe Syndrome)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Jaundice (Icterus)
Clinical Features
Treatment and Prognosis
◆ Amyloidosis
Clinical Features
Organ-Limited Amyloidosis
Systemic Amyloidosis
Primary and Myeloma-Associated Amyloidosis
Secondary Amyloidosis
Hemodialysis-Associated Amyloidosis
Heredofamilial Amyloidosis
Histopathologic Features
Diagnosis
Treatment and Prognosis
◆ Xanthelasma (Xanthelasma Palpebrarum)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Vitamin Deficiency
Clinical Features
Vitamin A
Thiamin
Riboflavin
Niacin
Pyridoxine
Vitamin C
Vitamin D
Vitamin E
Vitamin K
Treatment and Prognosis
◆ Iron-Deficiency Anemia
Clinical Features
Laboratory Findings
Treatment and Prognosis
◆ Plummer-Vinson Syndrome (Paterson-Kelly Syndrome; Sideropenic Dysphagia)
Clinical and Radiographic Features
Laboratory Findings
Histopathologic Features
Treatment and Prognosis
◆ Pernicious Anemia
Clinical Features
Histopathologic Features
Laboratory Findings
Treatment and Prognosis
◆ Pituitary Dwarfism
Clinical Features
Laboratory Findings
Treatment and Prognosis
◆ Gigantism
Clinical and Radiographic Features
Treatment and Prognosis
◆ Acromegaly
Clinical and Radiographic Features
Laboratory Findings and Diagnosis
Treatment and Prognosis
◆ Hypothyroidism (Cretinism; Myxedema)
Clinical Features
Laboratory Findings
Treatment and Prognosis
◆ Hyperthyroidism (Thyrotoxicosis; Graves Disease)
Clinical Features
Laboratory Findings
Histopathologic Features
Treatment and Prognosis
◆ Hypoparathyroidism
Clinical Features
Laboratory Findings
Treatment and Prognosis
◆ Pseudohypoparathyroidism (Albright Hereditary Osteodystrophy; Acrodysostosis)
Clinical Features
Treatment and Prognosis
◆ Hyperparathyroidism
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Hypercortisolism (Cushing Syndrome)
Clinical Features
Diagnosis
Treatment and Prognosis
◆ Addison Disease (Hypoadrenocorticism)
Clinical Features
Laboratory Findings
Treatment and Prognosis
◆ Diabetes Mellitus
Clinical Features
Type I Diabetes Mellitus
Type II Diabetes Mellitus
Complications
Treatment and Prognosis
◆ Hypophosphatasia
Clinical and Radiographic Features
Perinatal Lethal Hypophosphatasia
Perinatal Benign Hypophosphatasia
Infantile Hypophosphatasia
Childhood Hypophosphatasia
Adult Hypophosphatasia
Odontohypophosphatasia
Diagnosis
Histopathologic Features
Treatment and Prognosis
◆ Vitamin D–Resistant Rickets (Hereditary Hypophosphatemia; Familial Hypophosphatemic Rickets)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Crohn Disease (Regional Ileitis; Regional Enteritis)
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Pyostomatitis Vegetans
Clinical Features
Histopathologic Features
Treatment and Prognosis
◆ Uremic Stomatitis
Clinical Features
Treatment and Prognosis
Bibliography
Mucopolysaccharidosis
Lipid Reticuloendothelioses
Lipoid Proteinosis
Jaundice
Amyloidosis
Xanthelasma
Vitamin Deficiency
Iron-Deficiency Anemia
Plummer-Vinson Syndrome
Pernicious Anemia
Pituitary Dwarfism
Gigantism
Acromegaly
Hypothyroidism
Hyperthyroidism
Hypoparathyroidism
Pseudohypoparathyroidism
Hyperparathyroidism
Hypercortisolism
Addison Disease
Diabetes Mellitus
Hypophosphatasia
Vitamin D–Resistant Rickets
Crohn Disease
Pyostomatitis Vegetans
Uremic Stomatitis
18 Facial Pain and Neuromuscular Diseases
◆ Bell Palsy (Idiopathic Seventh Nerve Paralysis; Idiopathic Facial Paralysis)
Clinical Features
Treatment and Prognosis
◆ Frey Syndrome (Auriculotemporal Syndrome; Gustatory Sweating and Flushing)
Clinical Features
Treatment and Prognosis
Head and Neck Pain
◆ Trigeminal Neuralgia (Tic Douloureux; Tic)
Clinical Features
Treatment and Prognosis
◆ Glossopharyngeal Neuralgia (Vagoglossopharyngeal Neuralgia)
Clinical Features
Treatment and Prognosis
◆ Giant Cell Arteritis (Temporal Arteritis; Granulomatous Arteritis)
Clinical Features
Histopathologic and Laboratory Features
Treatment and Prognosis
◆ Burning Mouth Disorder (Stomatopyrosis; Stomatodynia; Glossopyrosis; Glossodynia; Burning Tongue Syndrome; Burning Mouth Syndrome)
Clinical Features
Treatment and Prognosis
◆ Dysgeusia and Hypogeusia (Phantom Taste; Distorted Taste)
Clinical Features
Treatment and Prognosis
◆ Osteoarthritis (Degenerative Arthritis; Degenerative Joint Disease)
Clinical and Radiographic Features
Histopathologic Features
Treatment and Prognosis
◆ Rheumatoid Arthritis
Clinical and Radiographic Features
Laboratory Values
Histopathologic Features
Treatment and Prognosis
◆ Temporomandibular Disorders
Clinical and Radiographic Features
Treatment and Prognosis
Bibliography
Bell Palsy
Frey Syndrome
Trigeminal Neuralgia
Glossopharyngeal Neuralgia
Giant Cell Arteritis
Burning Mouth Disorder
Dysgeusia and Hypogeusia
Osteoarthritis
Rheumatoid Arthritis
Temporomandibular Disorders
19 Forensic Dentistry
◆ Record Management
◆ Identification
Personal Recognition
Fingerprinting
Physical Anthropologic Examination of Bones and Teeth
Serologic and Genetic (DNA) Comparison
Dental Evaluation
Basic Principles
Guidelines for Dental Identification
Postmortem Examination
Antemortem Record Examination
Comparison of Antemortem and Postmortem Records and Written Conclusions
Dentistry’s Role in Multiple (Mass) Fatality Incident Identification
Natural Disasters
Accidents
Criminal Disasters
Responsibilities
Technologic Aids in Multiple Fatality Incident Analysis
◆ Bite Pattern Evidence
Basic Principles
Historical and Legal Issues
Characteristics of Bite Marks
Guidelines for Bite Mark Analysis
Description of the Bite Mark
Evidence Collection
Examination of the Victim and the Suspect
Photography
Saliva Evidence
Impressions and Study Casts
Tissue Samples
Evidence Analysis and Comparison
◆ Human Abuse
Epidemiology and Classification
Signs and Symptoms
Role of Dentistry in Recognizing and Reporting Human Abuse
◆ Dentists as Expert Witnesses
◆ Summary
Bibliography
Appendix Differential Diagnosis of Oral and Maxillofacial Diseases
Definitions
How to Use This Appendix
Index To The Appendix: Differential Diagnosis Lists
Part 1: Mucosal and Soft Tissue Pathology: Color Changes
Part 2: Mucosal and Soft Tissue Pathology: Surface Alterations
Part 3: Mucosal and Soft Tissue Pathology: Masses or Enlargements
Part 4: Radiographic Pathology
Part 5: Pathology of Teeth